15 completed, 8 unknown, 4 recruiting, 3 terminated. 13 Not applicable, 3 Phase 2, 3 Phase 4, 1 Phase 1.
Follow Cardiac Valve Disease: new trials by email Literature Review of Cardiac Valve Disease trials Research Report on Cardiac Valve Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Superficial Parasternal Block Combined With Rectus Sheath Block for Open Cardiac Surgery Parasternal and rectus sheath block, ropivacaine 0.25 % - Cardiac Valve Disease, Coronary Heart Disease | Phase 4 | Not yet recruiting | Hôpital du Valais | 100 | 2026-11-01 | 2026-10-22 |
| Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Cardiac Surgery fresh frozen plasma, prothrombin complex concentrate - Cardiac Valve Disease | Phase 4 | Recruiting | Konkuk University Medical Center | 100 | 2026-03-27 | 2026-06-17 |
| Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery Nicotinamide riboside, Placebo - Acute Kidney Injury, Cardiac Valve Disease | Not applicable | Unknown | Instituto Nacional de Cardiologia Ignacio Chavez | 100 | 2024-07-24 | 2024-07-25 |
| Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients Cardiac Infarct, Cardiac Valve Disease | Completed | University of Sao Paulo General Hospital | 200 | 2024-02-16 | 2026-06-22 | |
| Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients Ampicillin-sulbactam - Aortic Aneurysm and Dissection, Cardiac Valve Disease | Not applicable | Recruiting | Petrovsky National Research Centre of Surgery | 50 | 2024-01-23 | 2026-01-29 |
| Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries Intrathecal morphine or dexmedetomidine - Cardiac Valve Disease | Not applicable | Unknown | Assiut University | 40 | 2023-10-01 | 2023-10-11 |
| Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery Cardiac Valve Disease | Recruiting | Jena University Hospital | 100 | 2023-09-05 | 2025-09-26 | |
| Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit Open heart surgery group., Percutaneous cardiovascular surgery group. - Cardiac Disease, Cardiac Ischemia | Completed | Hospital Israelita Albert Einstein | 528 | 2023-09-01 | 2026-06-11 | |
| Optic Nerve Sheath Diameter is Associated With Postoperative Delirium in Patients Undergoing Open Heart Surgery ONSD - Delirium, Postoperative, Cardiac Disease | Completed | Samsun University | 90 | 2023-08-07 | 2024-09-05 | |
| The Effects of 360-degree Virtual Reality on Pre-procedural Anxiety in Patients Awaiting Elective Cardiac Surgery Involving a Sternotomy 360-degree Virtual Reality Patient Tour, State Trait Anxiety Inventory, Amsterdam Preoperative Anxiety and Information Scale - Cardiac Valve Disease, Aortic Valve Disease | Not applicable | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 100 | 2023-07-01 | 2024-07-10 |
| Telehealth Interventions for Cardiac Surgery Telehealth Monitoring - Cardiac Valve Disease, Coronary Artery Disease | Not applicable | Completed | Liverpool Heart and Chest Hospital NHS Foundation Trust | 318 | 2023-03-23 | 2026-10-19 |
| The Quality of Recovery-15 Survey After Cardiac Surgery Quality of Recovery 15 survey - Cardiac Disease, Surgery | Unknown | University of British Columbia | 160 | 2022-08-04 | 2022-11-02 | |
| The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) 3 DImensional Late Enhanced Gadolinium cardiac MRI scan - Mitral Valve Disease, Mitral Regurgitation | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 21 | 2022-02-02 | 2024-07-05 | |
| A Study to Objectively Measure Physical Activity and Sedentary Behavior During Cardiac Rehabilitation Cardiac Disease, Myocardial Infarction | Withdrawn | Mayo Clinic | 2022-01-01 | 2022-02-11 | ||
| Optic Nerve Sheath After Extracorporeal Circulation ultrasound measurement of the optic nerve sheath diameter, MoCA test - Cardiac Disease, Cardiac Valve Disease | Completed | University Medical Centre Maribor | 100 | 2021-11-22 | 2024-08-05 | |
| Ultrafiltration on Coagulation Performance in Cardiac Surgery ultrafiltration, maximal clot firmness in EXTEM assay of ROTEM test - Cardiac Valve Disease | Completed | Konkuk University Medical Center | 75 | 2021-08-01 | 2022-06-10 | |
| CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting Cardiac Valve Disease | Recruiting | Corcym S.r.l | 2150 | 2021-06-29 | 2024-03-06 | |
| Prescribed Sternal Precautions vs. Self-Guided Restrictive Care (PEEERC) Self Managed Care - Surgery, Heart Diseases | Not applicable | Terminated | University of Chicago | 10 | 2021-06-01 | 2025-11-10 |
| Nasal Oxygen Therapy After Cardiac Surgery High Flow Nasal Therapy - Cardiac Valve Disease, Coronary Artery Disease | Not applicable | Completed | Papworth Hospital NHS Foundation Trust | 1280 | 2020-09-08 | 2025-05-29 |
| Preoperative Optimization of Cardiac Valve Patients' Expectations EXPECT: Preoperative optimization of cardiac valve patient's expectations - Cardiac Valve Disease | Not applicable | Completed | Philipps University Marburg | 89 | 2020-07-17 | 2023-09-21 |
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Heart Valve Diseases (33) · Coronary Artery Disease (8) · Heart Diseases (6) · Acute Kidney Injury (2) · Atrial Fibrillation (2) · Coronary Disease (2) · Multiple Organ Failure (2) · Myocardial Infarction (2) · Thrombosis (2) · Angina Pectoris (1) · Aortic Aneurysm (1) · Aortic Aneurysm, Thoracic (1) · Aortic Dissection (1) · Aortic Valve Disease (1) · Aortic Valve Stenosis (1)
Cardiovascular Diseases (32) · Heart Diseases (27) · Vascular Diseases (16) · Pathological Conditions, Signs and Symptoms (12) · Myocardial Ischemia (11) · Pathologic Processes (11) · Arterial Occlusive Diseases (8) · Arteriosclerosis (8) · Coronary Disease (8) · Embolism and Thrombosis (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Infarction (2)
Ultrafiltration (2) · Acenocoumarol (1) · Acetylcysteine (1) · Dexmedetomidine (1) · Early Ambulation (1) · Factor IX (1) · Hydroxocobalamin (1) · Methylene Blue (1) · Morphine (1) · Physical Therapy Modalities (1) · Remote Patient Monitoring (1) · Saline Solution (1) · Valproic Acid (1) · nicotinamide-beta-riboside (1) · sultamicillin (1)
Konkuk University Medical Center (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Centre Chirurgical Marie Lannelongue (2) · University of Leicester (2) · University of Sao Paulo General Hospital (2) · Assiut University (1) · Corcym S.r.l (1) · Dartmouth-Hitchcock Medical Center (1) · Hospital Israelita Albert Einstein (1) · Hôpital du Valais (1) · Instituto Nacional de Cardiologia Ignacio Chavez (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Jena University Hospital (1) · Liverpool Heart and Chest Hospital NHS Foundation Trust (1) · Mayo Clinic (1)
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Sebastien Hascoet, MD, PhD (2) · Alana Flexman (1) · Amanda Bonikowske, PhD (1) · Andrew Klein (1) · Antonio Carcas, MD, PhD (1) · Ardawan Rastan, Prof. Dr. (1) · Boris Akselrod, Professor (1) · Gavin J Murphy, MD (1) · Gavin Murphy, MD (1) · Hany Moustafa (1) · Jolanda Kluin, M.D., PhD (1) · Jolanda Kluin, MD, PhD (1) · Keith B Allen, M.D. (1) · Madhu Natarajan, M.D. (1)
PMID 10681483, PMID 10693811, PMID 12067954, PMID 12952516, PMID 12974657, PMID 15151493, PMID 16363316, PMID 18191757, PMID 19623052, PMID 19664166, PMID 21110941, PMID 21651395, PMID 23782899, PMID 25303704, PMID 25386668, PMID 27127236, PMID 28869251, PMID 29599478, PMID 30127395, PMID 31673160, PMID 32791973, PMID 33393613, PMID 35699482, PMID 36937912, PMID 38902742, PMID 39666948, PMID 39827935, PMID 40072977, PMID 40596877, PMID 40918750, PMID 42236299, PMID 42633130, PMID 8166060, PMID 8598068, PMID 9783643
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