18 completed, 4 terminated, 3 withdrawn, 1 recruiting. 17 Not applicable, 3 Phase 3, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 12, Terminated 2, Withdrawn 2, Recruiting 1 |
| Phase 3 | 3 | Completed 2, Withdrawn 1 |
| Phase 4 | 3 | Completed 2, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dry Weight Reduction Intervention Via Extra Ultrafiltration Ultrafiltration - Fluid Accumulation, Blood Pressure Management | Not applicable | Recruiting | University of Washington | 120 | 2026-09-10 | 2026-10-30 |
| Usefulness of the VExUS Protocol for Dry-Weight Adjustment in Hemodialysis Patients: The Multicenter VExHD Study Increased ultrafiltration, No increase in ultrafiltration - Hypertension (HTN), Hemodialysis | Not applicable | Completed | Fundación Senefro | 72 | 2025-01-01 | 2026-06-24 |
| Fluid Currents During Hemodialysis Ultrafiltration - Patients Undergoing Hemodialysis | Unknown | Joachim Zdolsek | 30 | 2024-05-06 | 2024-05-01 | |
| Feasibility of Slow Continuous UltraFiltration For Deresuscitation in Critically Ill Patients Ultrafiltration - Fluid Overload | Not applicable | Completed | Belfast Health and Social Care Trust | 18 | 2022-08-12 | 2025-05-02 |
| High-exchange ULTrafiltration to Enhance Recovery After Pediatric Cardiac Surgery Ultrafiltration - Congenital Heart Disease | Not applicable | Completed | IWK Health Centre | 104 | 2021-09-28 | 2025-05-25 |
| Ultrafiltration on Coagulation Performance in Cardiac Surgery ultrafiltration, maximal clot firmness in EXTEM assay of ROTEM test - Cardiac Valve Disease | Completed | Konkuk University Medical Center | 75 | 2021-08-01 | 2022-06-10 | |
| Aquapheresis Efficacy in Outpatients With Decompensated Heart Failure Aquapheresis, IV Diuretics - Heart Failure, Congestive Heart Failure | Not applicable | Withdrawn | Ramona Gelzer Bell | 2021-06-08 | 2021-08-30 | |
| Ultrafiltration on Coagulation Function in Cardiac Surgery Ultrafiltration - Cardiac Valve Disease | Not applicable | Completed | Konkuk University Medical Center | 39 | 2020-01-30 | 2025-09-12 |
| Ultrafiltration Effect on Extravascular Lung Water in Pediatric Cardiac Surgery ultrafiltration - Congenital Cardiac Disorders | Not applicable | Completed | Kasr El Aini Hospital | 60 | 2017-05-15 | 2018-07-24 |
| A Feasibility Study of Peritoneal Ultrafiltration With a Wearable Device, CLS UF, That Adds a Glucose-salt Solution to the Intraperitoneal Fluid in the Device, in Order to Maintain a Stable Intraperitoneal Osmolarity and Thereby Enhance Ultrafiltration. Carry life system, ultrafiltration (CLS UF) - Ultrafiltration Failure | Not applicable | Completed | Triomed AB | 5 | 2017-04-20 | 2018-03-16 |
| Ultrafiltration Versus Medical Therapies in the Management of the Cardio Renal Syndrome ULTRAFILTRATION, ENHANCED MEDICAL TREATMENT - Cardio-renal Syndrome | Not applicable | Completed | Hospices Civils de Lyon | 108 | 2017-03-31 | 2026-10-14 |
| Effects of Fluid Balance Control in Critically Ill Patients diuretics, albumin, fluid restriction - Fluid Shifts, Critical Care | Not applicable | Completed | Central Hospital, Nancy, France | 1411 | 2016-06-01 | 2020-09-22 |
| Global rEgistry on decongestioN Therapy Using Less invasivE UltraFiltration periph. minimal invasive ultrafiltration - Acute Heart Failure, Cardiac Decompensation | Terminated | Fresenius Medical Care Deutschland GmbH | 104 | 2015-12-03 | 2021-08-05 | |
| CVP-guided Aquapheresis for the Treatment of Acute Congestion in Heart Failure Ultrafiltration - Heart Failure | Completed | Heinrich-Heine University, Duesseldorf | 9 | 2013-11-01 | 2015-03-17 | |
| Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure loop diuretic, tolvaptan, ultrafiltration - Acute Decompensated Heart Failure | Phase 4 | Completed | The Christ Hospital | 45 | 2013-05-01 | 2016-01-28 |
| Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment Isolated veno-venous ultrafiltration (AQ), IV Loop Diuretics (LD) - Heart Failure, Cardiac Failure | Not applicable | Terminated | Nuwellis, Inc. | 224 | 2012-01-01 | 2023-08-29 |
| Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics Loop diuretics (furosemide, torsemide, bumetanide), Ultrafiltration - Acute Decompensated Heart Failure | Not applicable | Terminated | University of Cincinnati | 4 | 2011-11-01 | 2016-12-05 |
| REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure Furosemide or Furosemide and Dopamine, Ultrafiltration - Acute Decompensated Heart Failure | Phase 4 | Terminated | Niguarda Hospital | 10 | 2011-02-01 | 2017-04-10 |
| The Role of Adrenomedullin on the Outcome of Severe Heart Failure: a Clinical Randomized Study clinical treatment, ultrafiltration, isovolumetric hemofiltration - Heart Failure | Not applicable | Withdrawn | Federal University of São Paulo | 2010-04-01 | 2016-11-04 | |
| Cardiorenal Interactions During Treatment of Acute Decompensated Heart Failure: Diuretics Versus Ultrafiltration ultrafiltration, diuretics - Acute Decompensated Heart Failure | Phase 3 | Completed | University Hospital, Ghent | 1 | 2010-02-01 | 2012-01-10 |
Showing 20 of 27. Sign in to see all of them.
Heart Failure (9) · Edema (5) · Cardio-Renal Syndrome (3) · Hypertension (3) · Heart Defects, Congenital (2) · Heart Valve Diseases (2) · Kidney Failure, Chronic (2) · Acute Kidney Injury (1) · Body Weight (1) · Coronary Artery Disease (1) · Critical Illness (1) · Hypertrophy, Left Ventricular (1) · Intra-Abdominal Hypertension (1) · Multiple Organ Failure (1) · Renal Insufficiency, Chronic (1)
Konkuk University Medical Center (2) · University Hospital, Ghent (2) · Belfast Health and Social Care Trust (1) · Central Hospital, Nancy, France (1) · Centro Cardiologico Monzino (1) · Christiana Care Health Services (1) · Duke University (1) · Federal University of São Paulo (1) · Fresenius Medical Care Deutschland GmbH (1) · Fundación Senefro (1) · Heinrich-Heine University, Duesseldorf (1) · Hospices Civils de Lyon (1) · IWK Health Centre (1) · Indiana University (1) · Joachim Zdolsek (1)
United States (8) · Sweden (3) · Belgium (2) · Brazil (2) · Canada (2) · France (2) · Germany (2) · Italy (2) · South Korea (2) · Egypt (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Ann-Cathrine Johansson, MD, PhD (1) · Antonio Santoro, MD (1) · Bryan Kestenbaum, MD, MS (1) · El Mehdi Siaghy (1) · Eric Hoste, MD, Phd (1) · Eugene S Chung, MD (1) · Fabrizio Oliva, MD (1) · Fredrik Sundelin, MD (1) · Henning T Baberg, MD (1) · Jon Silversides, PhD (1) · Jonathan Bodare, MD (1) · Kerry L. Lee, PhD (1) · Malte Kelm, MD (1)
PMID 35061249, PMID 19153263, PMID 19515473, PMID 19528362, PMID 20038754, PMID 20167684, PMID 21330484, PMID 22578899, PMID 23131078, PMID 24269855, PMID 25543972, PMID 26041600, PMID 26927285, PMID 28130379, PMID 31159739, PMID 31163974, PMID 36810101, PMID 3727139, PMID 37932787, PMID 39048932, PMID 39209495, PMID 41611197, PMID 42105307
2009 (1), R01DK062030 (1), R01DK141693 (1), U01HL084904 (1)