4 completed, 2 not yet recruiting, 1 active not recruiting, 1 recruiting. 2 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Cardiac Remodeling: new trials by email Literature Review of Cardiac Remodeling trials Research Report on Cardiac Remodeling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition Transdermal estradiol, Standard of care - non hormonal - Menopause, Perimenopause | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2026-11-01 | 2026-07-29 |
| Baxdrostat and Ventricular Remodeling Baxdrostat, Placebo - Cardiac Remodeling | Phase 3 | Not yet recruiting | Subodh Verma | 286 | 2026-06-30 | 2026-06-17 |
| Cardiac Morphology and Function in Individuals With Autonomic Dysreflexia Autonomic Dysreflexia, Spinal Cord Injuries and Disorders (SCI/D) | Recruiting | Swiss Paraplegic Research, Nottwil | 48 | 2026-06-01 | 2026-08-27 | |
| Effect of Genetic Polymorphism on the Clinical Outcome to SGLT2 Inhibitors in Heart Failure Patients SGLT2 inhibitor (Dapagliflozin 10mg) - Heart Failure - NYHA II - IV, Cardiac Fibrosis | Active not recruiting | Ain Shams University | 200 | 2023-11-22 | 2025-03-30 | |
| Paroxetine-mediated GRK2 Inhibition to Reduce Cardiac Remodeling After Acute Myocardial Infarction Paroxetine, Placebo oral capsule - Cardiac Remodeling, Myocardial Infarction | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 50 | 2017-10-26 | 2022-06-01 |
| AI-ECG for Time-Resolved Prediction of HFrEF Heart Failure, Heart Failure With Reduced Ejection Fraction | Completed | Shanghai Zhongshan Hospital | 286709 | 2014-02-01 | 2026-04-09 | |
| Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis Metoprolol succinate, placebo - Cirrhosis, Cirrhotic Cardiomyopathy | Phase 3 | Completed | University of Sao Paulo | 125 | 2012-01-01 | 2014-09-11 |
| Post-Myocardial Infarction Remodeling Prevention Therapy Single Site Pacing, Dual Site Pacing - Acute Myocardial Infarction, Pacing Therapy | Phase 2 | Completed | Medtronic Cardiac Rhythm and Heart Failure | 129 | 2010-12-01 | 2016-12-15 |
Heart Failure (2) · Autonomic Dysreflexia (1) · Cardiomyopathies (1) · Disease (1) · Fibrosis (1) · Myocardial Infarction (1) · Spinal Cord Injuries (1) · Ventricular Dysfunction, Left (1) · Ventricular Remodeling (1)
Cardiovascular Diseases (4) · Heart Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Autonomic Nervous System Diseases (1) · Central Nervous System Diseases (1) · Infarction (1) · Ischemia (1) · Myocardial Ischemia (1) · Necrosis (1) · Nervous System Diseases (1) · Pathological Conditions, Anatomical (1) · Spinal Cord Diseases (1) · Trauma, Nervous System (1) · Vascular Diseases (1)
Estradiol (1) · Gabapentin (1) · Gels (1) · Metoprolol (1) · Paroxetine (1) · Selective Serotonin Reuptake Inhibitors (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · dapagliflozin (1) · fezolinetant (1) · oxybutynin (1)
Ain Shams University (1) · Insel Gruppe AG, University Hospital Bern (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Medtronic Cardiac Rhythm and Heart Failure (1) · Shanghai Zhongshan Hospital (1) · Subodh Verma (1) · Swiss Paraplegic Research, Nottwil (1) · University of Sao Paulo (1)
Switzerland (2) · Brazil (1) · Canada (1) · China (1) · Denmark (1) · Egypt (1) · France (1) · Germany (1) · Hungary (1) · Saudi Arabia (1) · Slovakia (1) · United States (1)
Angel Leon, MD (1) · Bassem Zarif, MD (1) · Fernando Bacal, MD, PhD (1) · Gregg Stone, MD (1) · Subodh Verma, MD, PhD (1) · Thomas Pilgrim, MD (1)
PMID 26321236, PMID 34259826, PMID 36000427
2016 (1)