54 completed, 9 unknown, 7 recruiting, 4 active not recruiting. 19 Phase 3, 18 Phase 2, 17 Phase 4, 15 Not applicable, 6 Phase 1.
Follow oxybutynin: new trials by email Literature Review of oxybutynin trials Research Report on oxybutynin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition Transdermal estradiol, Standard of care - non hormonal - Menopause, Perimenopause | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2026-11-01 | 2026-07-29 |
| Parasacral TENS Project Parasacral transcutaneous electric nerve stimulation (TENS), Oxybutynin - Overactive Bladder (OAB), Lower Urinary Tract Dysfunction | Not applicable | Not yet recruiting | University of Virginia | 60 | 2026-09-30 | 2026-10-23 |
| Endotype DIrected Treatment for OSA in Down Syndrome ato-oxy, Oxygen - Obstructive Sleep Apnea (OSA), Down Syndrome | Phase 4 | Recruiting | University of Arizona | 200 | 2026-03-14 | 2026-09-03 |
| Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder Dysfunction Oxybutynin Hydrochloride, Placebo - Spina Bifida | Phase 3 | Recruiting | Central Hospital, Nancy, France | 60 | 2026-01-15 | 2026-04-14 |
| Behavioral Interventions Versus Pelvic Floor Muscle Therapy as Adjuncts to Anticholinergic Pharmacotherapy for Urgency Urinary Incontinence: A Non-Inferiority Trial Pelvic Floor Muscle Training (PFMT), Behavioral Bladder Training Program, Oxybutynin / Mirabegron (Standardized Pharmacotherapy) - Urgency Urinary Incontinence | Not applicable | Active not recruiting | Emilio José Dávila Álvarez | 80 | 2025-11-22 | 2026-01-26 |
| Comparative Study of the Efficacy of Treatment of Idiopathic Overactive Bladder (OAB) in Children: Oxybutynine vs. Transcutaneous Neurostimulation Oxybutynin, medical device Urostim - Overactive Bladder (OAB), Transcutaneous Neurostimulation | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 124 | 2025-11-05 | 2025-11-18 |
| Τhe Combination of Pharmacotherapy With RECOVERYTRSGR and RECOVERYTRSBDGR. Group A: (Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol,anxiolytics: clonazepam, stedon, tavor antidepressants: seropram),, Group B (Pharmacotherapy and TAU) (Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol, clonazepam, stedon, tavor, antidepressants,, Group C (Pharmacotherapy and Psychotherapy) Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol, clonazepam, stedon, tavor, lithium, depakine - Treatment Resistant Schizophrenia, Treatment Resistant Bipolar Disorder | Phase 4 | Active not recruiting | Dr. Stavroula Rakitzi | 84 | 2025-06-04 | 2026-05-01 |
| Efficacy and Safety of Mirabegron Versus Oxybutynin After Posterior Urethral Valve Ablation Mirabegron - Posterior Urethral Valve | Not applicable | Completed | South Valley University | 52 | 2025-01-01 | 2026-06-29 |
| Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea Atomoxetine 80mg combined with oxybutynin 5mg, Venlafaxine 37.5mg, oxybutynin 5mg combined with trazodone 100mg - Obstructive Sleep Apnea of Adult | Phase 4 | Completed | China Medical University Hospital | 45 | 2024-11-05 | 2026-04-23 |
| Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve. Tamsulosin, Oxybutynin, Trimethoprim/sulfamethoxazole (TMP/SMZ) - Posterior Urethral Valve | Phase 3 | Recruiting | Mansoura University | 50 | 2024-11-01 | 2024-12-20 |
| REDucing Hot FLASHes in Women Using Endocrine Therapy. Oxybutynin, Venlafaxine - Breast Cancer, Hot Flash Due to Medication | Phase 3 | Recruiting | Reinier de Graaf Groep | 260 | 2024-10-03 | 2025-02-04 |
| A Trial Evaluating the Clinical Efficacy and Safety of Hibero SR (Mirabegron) 50 mg and Ditropan (Oxybutynin Chloride) 10 mg in Children Between 5 and 18 Years With Overactive Bladder (OAB) Mirabegron 50 MG, Oxybutynin Chloride 5 MG - Overactive Bladder | Phase 2 | Unknown | Seoul National University Hospital | 44 | 2024-04-01 | 2024-03-08 |
| Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea Atomoxetine 80 mg plus Oxybutynin 5 mg, Atomoxetine 80 MG, Placebo - OSA | Phase 1 / Phase 2 | Completed | Brigham and Women's Hospital | 27 | 2023-12-01 | 2025-12-17 |
| A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats Fezolinetant, Paroxetine, Citalopram - Hot Flashes | Completed | Astellas Pharma Global Development, Inc. | 999 | 2023-11-15 | 2026-06-05 | |
| Effectiveness of Oral Boldo in Women With Overactive Bladder Oxybutynin Pill, Boldo supplement - Urinary Bladder, Overactive | Phase 1 | Unknown | Universidad de Valparaiso | 10 | 2023-11-01 | 2023-12-08 |
| Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome Atomoxetine and Oxybutynin (ato-oxy) - Obstructive Sleep Apnea, Down Syndrome | Phase 2 | Active not recruiting | University of Arizona | 36 | 2023-09-29 | 2026-04-07 |
| Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect? Topical oxybutynin spray, Topical placebo spray, Oral oxybutynin - Hyperhidrosis, Oxybutynin | Phase 2 | Unknown | Samantha Rodrigues Camargo Neves de Moura | 17 | 2022-09-26 | 2024-05-28 |
| Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy Atomoxetine, Oxybutynin - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Unknown | Brigham and Women's Hospital | 22 | 2022-05-05 | 2023-10-18 |
| Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer Oxybutynin Chloride, Placebo Administration, Quality-of-Life Assessment - Prostate Carcinoma | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 88 | 2021-10-28 | 2025-03-30 |
| Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure Methocarbamol, Oxybutynin - Kidney Calculi, Kidney Diseases | Not applicable | Active not recruiting | Northwestern University | 126 | 2021-09-30 | 2026-10-13 |
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Urinary Bladder, Overactive (22) · Hyperhidrosis (9) · Urinary Bladder, Neurogenic (7) · Urinary Incontinence (6) · Urinary Incontinence, Urge (6) · Sleep Apnea, Obstructive (5) · Down Syndrome (3) · Hot Flashes (3) · Spinal Cord Injuries (3) · Breast Neoplasms (2) · Hereditary Sensory and Autonomic Neuropathies (2) · Parkinson Disease (2) · Anxiety Disorders (1) · Body Odor (1) · Breast Carcinoma In Situ (1)
Brigham and Women's Hospital (5) · Alza Corporation, DE, USA (3) · Astellas Pharma Inc (3) · US Department of Veterans Affairs (3) · University of Arizona (3) · Watson Pharmaceuticals (3) · Astellas Pharma Singapore Pte. Ltd. (2) · China Medical University Hospital (2) · AbbVie (1) · Academic and Community Cancer Research United (1) · Adana Numune Training and Research Hospital (1) · Alliance for Clinical Trials in Oncology (1) · Antares Pharma Inc. (1) · Astellas Pharma Global Development, Inc. (1) · Astellas Scientific & Medical Affairs, Inc. (1)
United States (34) · Brazil (6) · Canada (6) · France (6) · Taiwan (5) · South Korea (4) · Germany (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Australia (2) · Belgium (2) · Egypt (2) · Greece (2) · Italy (2) · Netherlands (2)
Scott A Sands, PhD (3) · Daniel Combs, MD (2) · Gary Hoel, RPh, PhD (2) · Kathryn L. Burgio, PhD MA BA (2) · Aaron I Vinik, MD, PhD (1) · Aaron L Ellenbogen, DO, MPH (1) · Adrian S Wagg, MD (1) · Ahmad Abolyosr Mohamed, Professor (1) · Ahmed Elkashef (1) · Ahmet H Sevinc, MD, Urology Specialist (1)
PMID 37160401, PMID 19233423, PMID 19683731, PMID 26114588, PMID 37811598, PMID 12934777, PMID 19625056, PMID 19628264, PMID 20626389, PMID 20639023, PMID 20690893, PMID 21175373, PMID 21963104, PMID 22092152, PMID 22341836, PMID 23167161, PMID 23332882, PMID 23448285, PMID 24477421, PMID 24519200, PMID 27123229, PMID 29777865, PMID 30266334, PMID 30395486, PMID 31222714, PMID 31449805, PMID 33122028, PMID 36504158, PMID 36892754, PMID 37148497, PMID 37555595, PMID 38402104, PMID 38430402, PMID 38526612, PMID 41178302, PMID 41587370
2008 (1), P30CA015083 (1), R01AT007171 (1), R01HL146697 (1), R33HL151254 (1), R61HL151254 (1), UG1CA189823 (1), UL1TR001082 (1)