28 completed, 2 terminated, 1 unknown, 1 withdrawn. 20 Phase 1, 6 Phase 2, 6 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 20 | Completed 19, Terminated 1 |
| Phase 2 | 6 | Completed 4, Unknown 1, Withdrawn 1 |
| Phase 3 | 6 | Completed 5, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
Follow Quinidine: new trials by email Literature Review of Quinidine trials Research Report on Quinidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants. balcinrenone/ dapagliflozin, quinidine - Healthy Participants | Phase 1 | Completed | AstraZeneca | 14 | 2025-05-20 | 2025-08-12 |
| A Study to Investigate the Pharmacokinetics of AZD2389 in Healthy Participants When Administered Alone and in Combination With Quinidine AZD2389, Quinidine - Advanced Chronic Liver Disease, Healthy Participants | Phase 1 | Completed | AstraZeneca | 16 | 2025-05-12 | 2025-07-25 |
| A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323. EDP-323, Itraconazole, carbamazepine - RSV Infection, Drug Drug Interaction (DDI) | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 48 | 2025-01-27 | 2025-07-01 |
| A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants Orforglipron, Midazolam, Quinidine - Healthy | Phase 1 | Completed | Eli Lilly and Company | 27 | 2024-12-06 | 2026-05-26 |
| A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and Drug-Drug Interaction Study of NX-5948 in Healthy Volunteers NX-5948, Esomeprazole, Placebo - Healthy Volunteer | Phase 1 | Completed | Nurix Therapeutics, Inc. | 223 | 2024-11-30 | 2026-07-28 |
| A Study to Assess the Effect of Voriconazole and Quinidine on the Pharmacokinetics of a Single Dose of Repotrectinib in Healthy Participants Repotrectinib, Voriconazole, Quinidine - Healthy Volunteers | Phase 1 | Completed | Bristol-Myers Squibb | 32 | 2024-08-26 | 2025-08-22 |
| A Clinical Trial to Evaluate MK-4208/Embibatinib in Healthy Adult Participants (MK-4208-001/Embibatinib-1014) Embibatinib, Rabeprazole, Midazolam - Healthy | Phase 1 | Completed | Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 196 | 2023-12-21 | 2026-10-22 |
| Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects. EDP-235, Itraconazole, Carbamazepine - COVID-19 | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 36 | 2022-10-06 | 2023-04-27 |
| Quinidine Versus Verapamil in Short-coupled Idiopathic Ventricular Fibrillation Quinidine, Verapamil - Short-coupled Idiopathic Ventricular Fibrillation | Phase 2 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 24 | 2022-10-01 | 2023-09-13 |
| A Study of Imlunestrant (LY3484356) in Female Healthy Participants Imlunestrant, Repaglinide, Omeprazole - Healthy | Phase 1 | Completed | Eli Lilly and Company | 113 | 2022-07-07 | 2025-12-12 |
| Drug-Drug Interaction Study Between EDP-514, Itraconazole, Carbamazepine, and Quinidine in Healthy Subjects EDP-514, Itraconazole, Carbamazepin - Hepatitis B | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 72 | 2020-11-05 | 2021-08-16 |
| Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg), Placebo - Huntington Disease, Irritability | Phase 3 | Completed | The University of Texas Health Science Center, Houston | 20 | 2019-08-05 | 2024-01-05 |
| Impact of Nuedexta on Bulbar Physiology and Function in ALS dextromethorphan HBr and quinidine sulfate - Amyotrophic Lateral Sclerosis | Phase 1 / Phase 2 | Completed | University of Florida | 28 | 2019-07-25 | 2023-03-08 |
| Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects EDP-938, Itraconazole, Rifampin - RSV Infection | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 72 | 2018-11-29 | 2019-06-14 |
| Drug-drug Interaction Study Between EDP-305, Fluconazole and Quinidine in Healthy Volunteers Fluconazole, Quinidine, EDP-305 - NASH - Nonalcoholic Steatohepatitis | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 48 | 2018-07-19 | 2018-12-05 |
| Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants AVP-923 - Healthy Adult Male and Female Volunteers | Phase 1 | Completed | Avanir Pharmaceuticals | 17 | 2017-11-28 | 2018-02-23 |
| Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA) NUEDEXTA® - Pseudobulbar Affect (Involuntary Laughing and/or Crying) | Phase 4 | Terminated | Avanir Pharmaceuticals | 5 | 2015-09-01 | 2017-07-03 |
| Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects Ranolazine, Dofetilide, Verapamil - Drug-induced Surface ECG Changes | Phase 1 | Completed | Food and Drug Administration (FDA) | 22 | 2013-05-01 | 2018-03-08 |
| Clinical Trial Nuedexta in Subjects With ALS Nuedexta, Matching Placebo - Amyotrophic Lateral Sclerosis (ALS) | Phase 2 | Completed | Center for Neurologic Study, La Jolla, California, | 90 | 2013-04-01 | 2017-03-24 |
| Effect of P-glycoprotein Inhibition on Lenalidomide Pharmacokinetics in Healthy Males Lenalidomide, Quinidine, Temsirolimus - Healthy | Phase 1 | Completed | Celgene | 31 | 2012-10-01 | 2019-11-08 |
Showing 20 of 32. Sign in to see all of them.
Arrhythmias, Cardiac (4) · Amyotrophic Lateral Sclerosis (3) · Cardiovascular Diseases (3) · Heart Diseases (3) · Atrial Fibrillation (2) · Respiratory Syncytial Virus Infections (2) · Ventricular Fibrillation (2) · Autistic Disorder (1) · Brugada Syndrome (1) · COVID-19 (1) · Death, Sudden, Cardiac (1) · Depressive Disorder, Major (1) · Fasting (1) · Heart Arrest (1) · Hepatitis B (1)
Enanta Pharmaceuticals, Inc (5) · AstraZeneca (3) · Avanir Pharmaceuticals (3) · Eli Lilly and Company (3) · Boehringer Ingelheim (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Biosense Webster, Inc. (1) · Bristol-Myers Squibb (1) · Celgene (1) · Center for Neurologic Study, La Jolla, California, (1) · Food and Drug Administration (FDA) (1) · International Registry of Asymptomatic Brugada Syndrome (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Nurix Therapeutics, Inc. (1) · Sutter Health (1)
United States (23) · Netherlands (2) · Argentina (1) · Brazil (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Japan (1) · Kenya (1) · Switzerland (1) · United Kingdom (1)
H. Greene (2) · Adrian Hepner, M.D. (1) · Bo Fransson, MD (1) · Carlos Sanabria, MD (1) · Carol A Parise, PhD (1) · Christian van der Werf, MD PhD (1) · Edward O'Mara, MD (1) · Emily Plowman, PhD (1) · Erin L Furr Stimming, MD (1) · Jeremy Shefner, MD, PhD (1)
PMID 19029470, PMID 20839238, PMID 22032709, PMID 25054430, PMID 25870186, PMID 26324176, PMID 28036330, PMID 28036334, PMID 28213480, PMID 28974568, PMID 41499296
R01HL031472 (1), R01HL034071 (1)