7 completed, 3 terminated, 2 unknown, 1 withdrawn. 5 Phase 3, 5 Phase 4, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 4, Terminated 1 |
| Phase 4 | 5 | Completed 2, Terminated 2, Unknown 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
Follow Procainamide: new trials by email Literature Review of Procainamide trials Research Report on Procainamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevention of Post-Operative Cardiac Arrhythmias Dexmedetomidine, Magnesium Sulfate, Amiodarone - Cardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery | Phase 4 | Unknown | Jeffrey Moak | 870 | 2023-01-01 | 2022-03-15 |
| RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department Vernakalant, Procainamide - Atrial Fibrillation | Phase 4 | Completed | Ottawa Hospital Research Institute | 350 | 2021-06-17 | 2025-04-10 |
| Management of Supraventricular Tachycardia of Children adenosine,Propranolol,flecainide, amiodarone, propranolol, digoxin and procainamide. - Supraventricular Tachycardia | Unknown | Assiut University | 50 | 2018-05-15 | 2018-05-18 | |
| Acute Mechanical Response to Anti-arrhythmic Drug Therapy Procainamide - Arrhythmias | Not applicable | Withdrawn | Evan Adelstein, MD | 2015-10-01 | 2018-06-28 | |
| Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention Antiarrhythmic Drug Therapy, Catheter ablation - Ventricular Tachycardia, Ventricular Arrhythmia | Phase 4 | Terminated | Ottawa Heart Institute Research Corporation | 3 | 2014-10-01 | 2026-05-04 |
| Chemical vs Electrical Cardioversion for Emergency Department Patients With Acute Atrial Fibrillation Electrical-first, Chemical-first - Atrial Fibrillation | Phase 3 | Completed | University of British Columbia | 86 | 2013-11-01 | 2015-06-11 |
| ST-segment Elevation as an AF Endophenotype Procainamide - Atrial Fibrillation | Not applicable | Completed | Vanderbilt University Medical Center | 161 | 2010-11-01 | 2018-05-02 |
| Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias flecainide, ajmaline, procainamide - Atrial Fibrillation, Tachycardia, Ventricular | Phase 4 | Completed | Hospital Clinic of Barcelona | 123 | 2008-06-01 | 2010-12-15 |
| AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study FDA approved rate and rhythm control drugs, AV Node ablation and device implant - Atrial Fibrillation, Heart Failure | Phase 3 | Terminated | Mayo Clinic | 27 | 2007-12-01 | 2013-04-04 |
| Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia iv Amiodarone, iv Procainamide - Ventricular Tachycardia, Wide QRS Tachycardia | Phase 4 | Terminated | Hospital General Universitario Gregorio Marañon | 302 | 2005-09-01 | 2016-04-06 |
| Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) amiodarone, sotalol, propafenone - Arrhythmia, Atrial Fibrillation | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1995-03-01 | 2016-03-25 | |
| Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) amiodarone, imipramine, mexiletine - Arrhythmia, Cardiovascular Diseases | Phase 3 | Completed | University of Washington | 1987-04-01 | 2013-07-29 | |
| Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) electrophysiology, electrocardiography, ambulatory, imipramine - Arrhythmia, Cardiovascular Diseases | Phase 3 | Completed | University of Utah | 1985-07-01 | 2016-01-21 |
Atrial Fibrillation (6) · Arrhythmias, Cardiac (5) · Tachycardia, Ventricular (4) · Cardiovascular Diseases (3) · Heart Diseases (3) · Ventricular Fibrillation (2) · Brugada Syndrome (1) · Death, Sudden, Cardiac (1) · Emergencies (1) · Heart Arrest (1) · Heart Failure (1) · Myocardial Infarction (1) · Tachycardia, Supraventricular (1)
Assiut University (1) · Evan Adelstein, MD (1) · Hospital Clinic of Barcelona (1) · Hospital General Universitario Gregorio Marañon (1) · Jeffrey Moak (1) · Mayo Clinic (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Ottawa Heart Institute Research Corporation (1) · Ottawa Hospital Research Institute (1) · University of British Columbia (1) · University of Utah (1) · University of Washington (1) · Vanderbilt University Medical Center (1)
Canada (4) · United States (3) · Spain (2)
H. Greene (2) · Blanca Coll-Vinent, MD (1) · Carmen del Arco, MD (1) · Dawood Darbar, MD, PhD (1) · Dolores Vigil, MD (1) · Evan Adelstein, MD (1) · Fernando Arribas, MD (1) · Frank Scheuermeyer, MD (1) · Girish Nair, MD (1) · Ian G Stiell, MD, MSc (1) · Jeffrey Moak (1) · Mercedes Ortiz, PhD (1) · Rafael Peinado, MD (1)
PMID 1377359, PMID 16403928, PMID 1900101, PMID 19917887, PMID 22032709, PMID 22082198, PMID 28974568, PMID 41218981, PMID 9078197, PMID 9078198
2005 (1), R01HL031472 (1), R01HL034071 (1), U19HL065962 (1)