5 completed, 3 recruiting, 2 not yet recruiting, 1 enrolling by invitation. 6 Not applicable, 2 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Early Phase 1 | 1 | Recruiting 1 |
Follow Brain Aging: new trials by email Literature Review of Brain Aging trials Research Report on Brain Aging
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AKG and Brain Health in Aging Calcium AKG, Oral placebo capsules - Brain Aging, Cerebrovascular Function | Phase 2 | Not yet recruiting | University of Oklahoma | 60 | 2027-02-01 | 2026-10-06 |
| Multimodal Physiologic State Intelligence Study OMNIPHYS Multimodal Ultrasound Imaging System - Heart Failure, Cardiomyopathies | Enrolling by invitation | Truway Health, Inc. | 25000 | 2026-09-02 | 2026-09-10 | |
| Haematococcus Pluvialis Astaxanthin for Brain Aging Low-Dose AST, High-Dose AST, Placebo - Brain Aging | Not applicable | Not yet recruiting | Capital Medical University | 120 | 2026-05-01 | 2026-01-30 |
| LpD3.5 Intervention Study in Older Adults- LISA-I Trial LpD3.5, Placebo - Mild Cognitive Impairment (MCI), Cognition | Early Phase 1 | Recruiting | University of South Florida | 15 | 2026-03-03 | 2026-08-31 |
| The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults transcranial photobiomodulation - Cognition, Neurovascular Coupling Mechanism and Cognitive Function | Not applicable | Recruiting | University of Oklahoma | 30 | 2025-10-01 | 2026-02-06 |
| ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults Alpha-Linolenic Acid (2.6 g/day), Placebo Control Group - Cognitive Dysfunction, Alzheimer Disease | Phase 2 | Recruiting | Michal Schnaider Beeri, Ph.D. | 20 | 2025-01-12 | 2026-02-06 |
| AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults Avocado Group - Brain Aging | Not applicable | Unknown | University of Kansas Medical Center | 70 | 2024-04-09 | 2024-08-22 |
| Blueberry Intervention Study for Brain Aging Intervention, Control - Brain Aging | Not applicable | Completed | University of Kansas Medical Center | 63 | 2022-06-01 | 2025-05-21 |
| Milk Intervention Study for Brain Aging 1% Milk, Control - Brain Aging | Not applicable | Completed | University of Kansas Medical Center | 70 | 2017-04-07 | 2021-05-19 |
| Committed Actions for Successful Aging CASA - Brain Aging | Not applicable | Completed | Mayo Clinic | 10 | 2016-05-01 | 2020-03-18 |
| Synaptic Plasticity Imaging With Diffusion MRI Brain Aging | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 35 | 2011-12-05 | 2026-07-22 | |
| CARDIA Brain MRI Substudy Brain Aging, Obesity | Completed | National Institute on Aging (NIA) | 719 | 2010-12-22 | 2018-04-05 |
Cognitive Dysfunction (2) · Acute Kidney Injury (1) · Alzheimer Disease (1) · Aortic Diseases (1) · Apolipoprotein E, Deficiency or Defect of (1) · Cardiomyopathies (1) · Clinical Deterioration (1) · Diabetes Mellitus (1) · Disease (1) · Heart Failure (1) · Heart Valve Diseases (1) · Hypertension (1) · Hypertension, Pulmonary (1) · Inflammation (1) · Intracranial Aneurysm (1)
Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Cognition Disorders (2) · Mental Disorders (2) · Nervous System Diseases (2) · Neurocognitive Disorders (2) · Aneurysm (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Atherosclerosis (1) · Body Weight (1) · Cardiovascular Diseases (1) · Cerebrovascular Disorders (1)
Corn Oil (1) · Linseed Oil (1) · Methods (1) · Milk (1) · alpha-Linolenic Acid (1)
University of Kansas Medical Center (3) · University of Oklahoma (2) · Capital Medical University (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Mayo Clinic (1) · Michal Schnaider Beeri, Ph.D. (1) · National Institute on Aging (NIA) (1) · Truway Health, Inc. (1) · University of South Florida (1)
United States (9) · France (1)
In-Young Choi, PhD (2) · Andriy Yabluchanskiy, MD, PhD (1) · Gavin C Solomon, M.D. (1) · Lenore J Launer, Ph.D. (1) · Linhong Yuan, Doctor (1) · Michal Beeri, PHD (1) · Yonas E Geda, MD (1)
PMID 25948052, PMID 26106263, PMID 27763627, PMID 28709450, PMID 29282327, PMID 29682542, PMID 31814084, PMID 32129462, PMID 32302292, PMID 34500036, PMID 35535879, PMID 35573092, PMID 36046132, PMID 37213047, PMID 37224131
R21AG103782 (1)