24 completed, 7 recruiting, 5 not yet recruiting, 4 unknown. 20 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 10, Not yet recruiting 4, Recruiting 3, Active not recruiting 2, Terminated 1 |
Follow this condition Literature Review of Clinical Deterioration trials Research Report on Clinical Deterioration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training Generative AI-integrated Blended Simulation, High Fidelity Simulation - Clinical Reasoning in Nursing Education, Virtual Simulation | Not applicable | Not yet recruiting | National University of Singapore | 200 | 2026-10-12 | 2026-10-21 |
| Hospital-Onset Sepsis Systematic Detection and Structured Interventions Algorithm-triggered sepsis alert with structured critical care team activation - Sepsis, Deterioration, Clinical | Not applicable | Not yet recruiting | Patricks Lyons | 3700 | 2026-10-01 | 2026-09-04 |
| Multimodal Physiologic State Intelligence Study OMNIPHYS Multimodal Ultrasound Imaging System - Heart Failure, Cardiomyopathies | Enrolling by invitation | Truway Health, Inc. | 25000 | 2026-09-02 | 2026-09-10 | |
| Cognitive Outcomes in BAD-related Stroke END exposure - Branch Atheromatous Disease, Cognitive | Not yet recruiting | Peking Union Medical College Hospital | 60 | 2026-09-01 | 2026-08-12 | |
| Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm Validation Continuous vital sign monitoring - Postoperative Care, Deterioration, Clinical | Not applicable | Not yet recruiting | Eske Kvanner Aasvang | 100 | 2026-05-28 | 2026-06-16 |
| Repeated Examinations for Typing Pulmonary Embolism Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute | Recruiting | Sahlgrenska University Hospital | 400 | 2026-04-01 | 2026-10-13 | |
| Wireless Assessment of Respiratory and Circulatory Distress - Europe WARD-CSS (Wireless Assessment of Respiratory and Circulatory Distress - Clinical Support System) - Patient Deterioration, Patient Monitoring | Not applicable | Not yet recruiting | Eske Kvanner Aasvang | 1240 | 2026-03-16 | 2026-03-05 |
| Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-Pediatric PICTURE-Pediatric scores and alerts, Control Arm - Scores and alerts hidden - Clinical Deterioration | Not applicable | Recruiting | University of Michigan | 375 | 2026-02-09 | 2026-03-05 |
| Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission Home-based Clinical Assessment and Treatment - Nursing Homes Residents, Deterioration, Clinical | Not applicable | Recruiting | Copenhagen University Hospital at Herlev | 9000 | 2026-02-01 | 2026-09-02 |
| EWSs and 28-Day Mortality in Geriatric ED Patients Demographic Characteristics, Comorbidities, Vital Signs - Mortality, Clinical Deterioration | Completed | Haseki Training and Research Hospital | 2744 | 2025-07-01 | 2026-05-11 | |
| Multicomponent Exercise to Prevent Hospitalization-Associated Disability Behavioral: Exercise - Clinical Deterioration | Not applicable | Recruiting | Fundacion Miguel Servet | 300 | 2025-02-01 | 2026-07-16 |
| Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults Exercise - Clinical Deterioration | Not applicable | Completed | Fundacion Miguel Servet | 214 | 2025-02-01 | 2026-10-20 |
| A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning eCARTv5 clinical deterioration monitoring, Standard of care control - Sepsis, Septicemia | Not applicable | Active not recruiting | AgileMD, Inc. | 30000 | 2024-12-31 | 2025-07-29 |
| MRSI Evaluation for Minor Stroke With Large Vessel Occlusion Magnetic resonance spectroscopic imaging - Acute Ischemic Stroke | Recruiting | Shanghai 6th People's Hospital | 75 | 2024-08-15 | 2024-10-16 | |
| Wearable Wireless Respiratory Monitoring System That Detects and Predicts Opioid Induced Respiratory Depression Respiratory Monitoring System - Respiratory Insufficiency, Clinical Deterioration | Completed | Jeffrey Joseph | 14 | 2024-05-01 | 2025-10-15 | |
| Image-based Remote Monitoring in Cardiac Surgery Patients Image-based vital sign monitoring - Vital Signs, Clinical Deterioration | Completed | Catharina Ziekenhuis Eindhoven | 60 | 2024-02-23 | 2025-04-11 | |
| Personalised Real-time Interoperable Sepsis Monitoring (PRISM) PRISM Tool - Sepsis, Abdominal Sepsis | Withdrawn | Aisthesis Medical P.C. | 2023-11-29 | 2026-04-09 | ||
| VitalThings Guardian Contactless Monitoring Vitalthings Guardian M10 fixed and M10 mobile - Respiratory Depression, Respiratory Failure | Completed | VitalThings | 41 | 2023-11-15 | 2023-12-05 | |
| Observational Study of Early Postoperative Deterioration and Complications Postoperative Complications, Deterioration, Clinical | Completed | Copenhagen University Hospital, Hvidovre | 240 | 2023-10-03 | 2026-01-21 | |
| Continuous Monitoring of Vital Signs at Home (WARD HOME II) Continuously monitoring - Vital Sign Monitoring, Clinical Deterioration | Completed | Bispebjerg Hospital | 83 | 2023-10-03 | 2026-03-13 |
Showing 20 of 46. Sign in to see all of them.
Sepsis (6) · Pulmonary Embolism (5) · Heart Arrest (3) · Respiratory Insufficiency (3) · Thrombosis (3) · Disease (2) · Disease Progression (2) · Infections (2) · Motor Activity (2) · Postoperative Complications (2) · Pulmonary Disease, Chronic Obstructive (2) · Acute Disease (1) · Acute Kidney Injury (1) · Agnosia (1)
Pathologic Processes (46) · Pathological Conditions, Signs and Symptoms (46) · Disease Attributes (45) · Disease Progression (44) · Respiratory Tract Diseases (11) · Cardiovascular Diseases (10) · Lung Diseases (8) · Vascular Diseases (7) · Inflammation (6) · Respiration Disorders (6) · Systemic Inflammatory Response Syndrome (6) · Embolism (5) · Embolism and Thrombosis (5) · Infections (5) · Heart Diseases (4)
Comorbidity (1) · Continuous Glucose Monitoring (1) · Early Warning Score (1) · Exercise (1) · Injury Severity Score (1) · Positron-Emission Tomography (1) · Therapeutics (1)
Bispebjerg Hospital (3) · Shengjing Hospital (3) · Erzincan University (2) · Eske Kvanner Aasvang (2) · Fundacion Miguel Servet (2) · University Hospital Bispebjerg and Frederiksberg (2) · AgileMD, Inc. (1) · Aisthesis Medical P.C. (1) · Biobeat Technologies Ltd. (1) · Catharina Ziekenhuis Eindhoven (1) · Consorci Sanitari de l'Alt Penedès i Garraf (1) · Copenhagen University Hospital at Herlev (1) · Copenhagen University Hospital, Hvidovre (1) · Copenhagen University Hospital, Rigshospitalet (1) · Haseki Training and Research Hospital (1)
Denmark (11) · United States (9) · China (6) · Netherlands (4) · Spain (4) · Turkey (Türkiye) (4) · Norway (2) · United Kingdom (2) · Canada (1) · Greece (1) · Israel (1) · Poland (1) · Portugal (1) · Sweden (1)
Emilie Sigvardt, MD (2) · Adem Az (1) · Alex Davis, PhD (1) · Andrew JE Seely, MD, PhD, FRCSC (1) · Carine JM Doggen, Prof PhD (1) · Cristina Ramos, Nurse (1) · Dana P Edelson, MD, MS (1) · Deepika Mohan, MD (1) · Eleni Arnaoutoglou, MD, PhD (1) · Eske K Aasvang, DMSci (1) · Eske K Aasvang, MD,Med.Sc.D. (1) · Gad Segal, MD (1) · Gavin C Solomon, M.D. (1)
PMID 20637974, PMID 22875955, PMID 23440923, PMID 24857401, PMID 28926736, PMID 31601602, PMID 31915173, PMID 32252135, PMID 32434791, PMID 33944790, PMID 34043525, PMID 35298560, PMID 35599143, PMID 35679119, PMID 35794669, PMID 35832414, PMID 37316919, PMID 37331563, PMID 38380992, PMID 38619713, PMID 39665054, PMID 40576035, PMID 40742731, PMID 40997056, PMID 41047463, PMID 41174707, PMID 41644641, PMID 41804675