15 completed, 2 recruiting, 2 unknown, 1 active not recruiting. 10 Not applicable, 3 Phase 4, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 8, Recruiting 1, Terminated 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Blood Loss, Postoperative: new trials by email Literature Review of Blood Loss, Postoperative trials Research Report on Blood Loss, Postoperative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony Calcium Gluconate, Saline - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 2 | Recruiting | University of Michigan | 140 | 2025-10-20 | 2026-07-24 |
| Tranexamic Acid Versus Misoprostol to Reduce Blood Loss During and After Cesarean Section Intravenous Tranexamic Acid, rectal misoprostol - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 4 | Completed | Medicare Hospital (Pvt) Limited | 214 | 2025-03-01 | 2026-07-17 |
| EFFICACY OF INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION ON THE POSTOPERATIVE BLOOD LOSS IN PATIENTS UNDERGOING RARP FOR THE TREATMENT OF PROSTATE CANCER Arm A - Application of 5g of ARISTA™ AH - Prostate Cancer (Adenocarcinoma), Blood Loss, Postoperative | Not applicable | Recruiting | St. Antonius Hospital Gronau | 362 | 2025-01-16 | 2026-05-29 |
| Comparing Tranexamic Acid Versus Ecbolics in Preventing Hemorrhage During and After Cesarean Section Tranexamic acid - Postpartum Hemorrhage, Blood Loss, Postoperative | Not applicable | Completed | Cairo University | 440 | 2023-10-15 | 2024-07-23 |
| Comparative Study Between Preoperative and Postoperative Rectal Misoprostol Misoprostol - Blood Loss, Surgical, Blood Loss, Postoperative | Not applicable | Completed | Egymedicalpedia | 128 | 2023-08-31 | 2024-08-20 |
| EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDY Intervention with Tranexamic Acid, Control group (Normal Saline) - Blood Loss, Postoperative, Blood Loss, Surgical | Not applicable | Completed | Kathmandu University School of Medical Sciences | 54 | 2023-01-01 | 2026-06-04 |
| Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline) Oxytocin - Blood Loss, Surgical, Blood Loss, Postoperative | Not applicable | Completed | Egymedicalpedia | 300 | 2022-03-20 | 2023-02-08 |
| Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D) Sham comparator, DrugSorb-ATR system - Hemorrhage, Surgical, Hemorrhage Postoperative | Not applicable | Terminated | CytoSorbents, Inc | 9 | 2021-12-27 | 2025-05-04 |
| Safe and Timely Antithrombotic Removal (STAR) Registry CytoSorb - Hemorrhage, Surgical, Hemorrhage Postoperative | Active not recruiting | CytoSorbents, Inc | 1000 | 2021-09-30 | 2026-10-21 | |
| Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T) DrugSorb-ATR system, Sham comparator - Hemorrhage, Surgical, Blood Loss, Surgical | Not applicable | Completed | CytoSorbents, Inc | 140 | 2021-08-31 | 2026-10-26 |
| Blood Loss Quantification During Major Abdominal Surgery Measurement of external blood loss, Serum Hemoglobin concentration - Blood Loss, Surgical, Blood Loss, Postoperative | Unknown | University of Defence, Faculty of Military Health Sciences | 45 | 2021-05-01 | 2022-04-07 | |
| IV Ketorolac on Platelet Function Post-Cesarean Delivery Ketorolac Tromethamine 30 MG/ML, Placebos - Analgesia, Obstetrical, Coagulation Defect; Postpartum | Phase 4 | Completed | Beth Israel Deaconess Medical Center | 40 | 2021-01-18 | 2026-05-29 |
| Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Oxytocin ,Tranexamic acid and Ethamsylate - Blood Loss, Surgical, Blood Loss, Postoperative | Phase 1 / Phase 2 | Completed | Egymedicalpedia | 230 | 2020-04-01 | 2022-03-17 |
| The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery before uterine incision oxytocin, after clamping the umbilical cord oxytocin - Cesarean Section Complications, Postpartum Hemorrhage | Not applicable | Completed | Bezmialem Vakif University | 101 | 2019-05-01 | 2019-09-24 |
| Fibrin Clot Properties and Blood Loss Following Coronary Artery By-pass Grafting Skeletonized LIMA, Pedicled LIMA - Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis | Not applicable | Completed | Jagiellonian University | 62 | 2018-09-26 | 2020-02-12 |
| Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty iced normal saline, Tranexamic acid injection, Cocktail (composing by Ropivacaine, Morphine and Epinephrine) perfusion - Pain, Postoperative, Blood Loss, Postoperative | Not applicable | Completed | Yantai Yuhuangding Hospital | 60 | 2018-03-02 | 2022-01-24 |
| Individualized Multimodal Hemostasis Evaluation Pyramid (IMHOTEP) Coagulation factor levels - Blood Loss, Postoperative, Liver Transplant | Completed | Semmelweis University | 59 | 2017-08-01 | 2020-09-02 | |
| Estimated Blood Loss: Novel Model for Estimating Surgical Blood Loss. Measurement of external blood loss, Serum Hemoglobin concentration - Blood Loss, Surgical, Blood Loss | Completed | Hospital Clinic of Barcelona | 100 | 2017-01-01 | 2024-10-29 | |
| Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery Ketorolac, Placebo - Analgesia, Obstetrical, Postpartum Hemorrhage | Phase 4 | Completed | University Hospitals Cleveland Medical Center | 70 | 2016-05-01 | 2022-06-07 |
| Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery Tranexamic Acid (Oral), Tranexamic Acid (Intravenous) - Osteoarthritis, Blood Loss, Surgical | Phase 3 | Unknown | The New England Baptist Hospital | 118 | 2015-04-01 | 2016-03-22 |
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Postoperative Hemorrhage (21) · Blood Loss, Surgical (15) · Hemorrhage (7) · Pain, Postoperative (4) · Postpartum Hemorrhage (4) · Hemostatic Disorders (3) · Agnosia (2) · Pain (2) · Uterine Inertia (2) · Adenocarcinoma (1) · Coronary Artery Disease (1) · Femoral Fractures (1) · Fractures, Bone (1) · Osteoarthritis (1) · Postoperative Complications (1)
Pathologic Processes (21) · Pathological Conditions, Signs and Symptoms (21) · Postoperative Complications (20) · Intraoperative Complications (15) · Hemorrhage (14) · Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (5) · Obstetric Labor Complications (5) · Pregnancy Complications (5) · Cardiovascular Diseases (4) · Neurologic Manifestations (4) · Puerperal Disorders (4) · Signs and Symptoms (4) · Uterine Hemorrhage (4) · Vascular Diseases (4)
Tranexamic Acid (5) · Oxytocin (4) · Ethamsylate (2) · Ketorolac (2) · Ketorolac Tromethamine (2) · Misoprostol (2) · Saline Solution (2) · Calcium Gluconate (1) · Control Groups (1) · Epinephrine (1) · Methods (1) · Morphine (1) · Perfusion (1) · Sodium Chloride (1) · carbetocin (1)
CytoSorbents, Inc (3) · Egymedicalpedia (3) · Beth Israel Deaconess Medical Center (1) · Bezmialem Vakif University (1) · Cairo University (1) · Chiang Mai University (1) · Hospital Clinic of Barcelona (1) · Jagiellonian University (1) · Kathmandu University School of Medical Sciences (1) · Medicare Hospital (Pvt) Limited (1) · Semmelweis University (1) · St. Antonius Hospital Gronau (1) · The New England Baptist Hospital (1) · University Hospitals Cleveland Medical Center (1) · University of Defence, Faculty of Military Health Sciences (1)
United States (6) · Egypt (4) · Germany (2) · Austria (1) · Belgium (1) · Canada (1) · China (1) · Czechia (1) · Hungary (1) · Nepal (1) · Pakistan (1) · Poland (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1)
C. M Gibson, MD (2) · Michael J Mack, MD (2) · Amr K Rasheed, MsC (1) · AnneMarie Opipari, MD (1) · Jan Zajak, MD, MA (1) · Kenneth Bauer, MD (1) · Laijian Sui, Doctor (1) · Michael Schmoeckel, Prof, MD (1) · Piotr Mazur, MD (1) · Richard Whitlock, MD (1) · Sami-Ramzi Leyh-Bannurah, PD (1) · Shahid I Rao, FCPS (1) · Uwe Zeymer, Prof, MD (1)
PMID 35657375, PMID 27536161, PMID 28040124, PMID 28938281, PMID 30122082, PMID 33532495, PMID 38166991, PMID 38709456, PMID 39833891, PMID 40044567, PMID 40763214, PMID 40933270, PMID 41642317