17 completed, 6 unknown, 3 recruiting, 2 active not recruiting. 33 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 33 | Completed 17, Unknown 6, Recruiting 3, Active not recruiting 2, Not yet recruiting 2, Terminated 2, Withdrawn 1 |
Follow Atrophy: new trials by email Literature Review of Atrophy trials Research Report on Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment Evaluates Whether a 12-week Exercise and Individualized Nutrition Program Can Reduce Muscle and Bone Loss and Improve Strength, Fitness, and Function in Obese Adults on GLP-1 Semaglutide, Dietary Counseling, Exercise - GLP - 1, Obesity & Overweight | Phase 4 | Not yet recruiting | William Marsh Rice University | 20 | 2026-04-06 | 2026-04-28 |
| Restoring Facial Volume After GLP-1 Weight Loss With Radiesse Hyperdiluted Calcium Hydroxylapatite, Calcium hydroxylapatite, Calcium hydroxylapatite with integral lidocaine - Volume Loss (Soft Tissue Ptosis or Atrophy ) | Phase 4 | Recruiting | Kalpna Kay Durairaj, MD, FACS | 48 | 2026-02-01 | 2026-09-09 |
| Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients Roxadustat, Recombinant human erythropoietin (EPO) - Sarcopenia, Anemia Associated With Chronic Kidney Disease (CKD) | Phase 4 | Not yet recruiting | Tianjin Medical University General Hospital | 60 | 2025-09-10 | 2025-09-09 |
| GLP-1s to Enhance Lasting Optimal Weight Tirzepatide - Obesity | Phase 4 | Active not recruiting | Wake Forest University Health Sciences | 40 | 2025-07-07 | 2026-10-02 |
| Branched Chain Amino Acids for Sarcopenia in Patients Undergoing Total Knee Arthroplasty Livact Granule - Sarcopenia, Total Knee Arthroplasty | Phase 4 | Recruiting | Seoul National University Hospital | 140 | 2025-02-06 | 2026-06-09 |
| Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia exercise, whey protein powder, Eldecalcitol - Sarcopenia | Phase 4 | Recruiting | Zhejiang Provincial People's Hospital | 450 | 2024-06-16 | 2024-08-05 |
| Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients alfacalcidol, placebo, Denosumab - Sarcopenia | Phase 4 | Unknown | Yonsei University | 340 | 2024-02-13 | 2024-02-22 |
| Muscle Impact of Treating Osteoporosis Denosumab, Zoledronic Acid, Denosumab Placebo - Sarcopenia, Osteoporosis | Phase 4 | Completed | Nami Safai Haeri | 20 | 2023-02-14 | 2026-10-27 |
| Bioindicators Associated With Sarcopenia Before and After Intensive Lifestyle Intervention 3-month intensive intervention - Sarcopenia | Phase 4 | Completed | Lijun Yang | 99 | 2022-03-01 | 2023-11-13 |
| Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) (OFELIA) OAV101 - Muscular Atrophy, Spinal | Phase 4 | Completed | Novartis Pharmaceuticals | 16 | 2021-11-04 | 2024-10-09 |
| Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program Knee strengthening exercises with isokinetic dynamometer, Strengthening around the knees with home exercise programe - Osteoarthritis of the Knee, Sarcopenia | Phase 4 | Unknown | Sema Dağcı | 60 | 2021-08-18 | 2021-08-25 |
| Testosterone in Bariatric Patients Testosterone Undecanoate - Bariatric Surgery Candidate, Male Hypogonadism | Phase 4 | Completed | Esbjerg Hospital - University Hospital of Southern Denmark | 64 | 2020-12-17 | 2026-09-11 |
| The Effect of Intradialytic Parenteral Nutrition on Nutritional Status and Quality of Life in Hemodialysis Patients Olimel N12, Glucose IV - End Stage Renal Disease, Malnutrition | Phase 4 | Active not recruiting | Erasmus Medical Center | 166 | 2019-09-16 | 2026-02-12 |
| Role of AST120 for Sarcopenia Prevention in Pre-dialysis Chronic Kidney Disease Renamezin - Chronic Kidney Diseases | Phase 4 | Completed | Gumi Cha Medical Center | 150 | 2018-11-23 | 2020-12-17 |
| Mediterranean Diet, Circuit Resistance Training, Empagliflozin in Elderly With Type 2 Diabetes: a Study Protocol Circuit resistance training (CRT), Vegeterranean diet (V-Med diet), Empagliflozin 10 MG - Diabetes Mellitus, Type 2, Sarcopenia | Phase 4 | Completed | Tel-Aviv Sourasky Medical Center | 100 | 2018-05-09 | 2025-09-04 |
| The Impact of N-Acetylcysteine on Volumetric Retention of Autologous Fat Graft for Breast Asymmetry Correction N-Acetylcysteine (NAC) - Breast; Deformity, Congenital, Graft Loss | Phase 4 | Unknown | Centre of Postgraduate Medical Education | 15 | 2017-07-04 | 2017-07-06 |
| Effects of Supplementation of Vitamin D in Patients With Crohn's Disease Vitamin D, Placebo - Crohn Disease, Vitamin D Deficiency | Phase 4 | Unknown | Federal University of Juiz de Fora | 110 | 2016-12-01 | 2018-06-29 |
| LPD+α-ketoacids on Autophagy and Improving Muscle Wasting in CKD keto-amino acids - Muscular Atrophy | Phase 4 | Unknown | YUAN Wei-jie | 60 | 2016-11-01 | 2016-11-01 |
| The Effects of Long Term Cyclic Testosterone Administration on Muscle Function and Bone in Older Men Testosterone enanthate, Placebo - Sarcopenia | Phase 4 | Withdrawn | The University of Texas Medical Branch, Galveston | 2016-01-01 | 2015-10-02 | |
| Body Composition Measurements in Chronic Heart Failure bioelectrical impedance analysis (Bodystat, Quadscan 4000), dual-energy X-ray absorptiometry (Hologic, Delphi QDR), hand grip strength - Cachexia, Sarcopenia | Phase 4 | Unknown | Hungarian Institute of Cardiology | 35 | 2016-01-01 | 2016-02-22 |
Showing 20 of 33. Sign in to see all of them.
Sarcopenia (20) · Muscular Atrophy (9) · Muscular Diseases (3) · Obesity (3) · Weight Loss (3) · Frailty (2) · Muscle Weakness (2) · Anemia (1) · Bone Diseases, Metabolic (1) · Brain Injuries (1) · Bulbo-Spinal Atrophy, X-Linked (1) · Cachexia (1) · Congenital Abnormalities (1) · Critical Illness (1)
Pathological Conditions, Anatomical (33) · Pathological Conditions, Signs and Symptoms (33) · Nervous System Diseases (29) · Neurologic Manifestations (29) · Neuromuscular Manifestations (29) · Signs and Symptoms (29) · Muscular Atrophy (20) · Musculoskeletal Diseases (8) · Nutritional and Metabolic Diseases (8) · Pathologic Processes (8) · Body Weight (6) · Nutrition Disorders (6) · Body Weight Changes (4) · Disease Attributes (4)
Exercise (3) · Testosterone (3) · Denosumab (2) · Vitamin D (2) · testosterone enanthate (2) · 1-((2-hydroxyethyl)amino)-2-amino-1,2-dideoxyglucose triphenyltin(IV) (1) · Absorptiometry, Photon (1) · Acetylcysteine (1) · Allopurinol (1) · Amino Acids (1) · Botulinum Toxins, Type A (1) · Filgrastim (1) · Gels (1) · Hand Strength (1) · Lactose (1)
Novartis Pharmaceuticals (2) · The University of Texas Medical Branch, Galveston (2) · Wake Forest University Health Sciences (2) · Beer, Kenneth R., M.D., PA (1) · Boston Medical Center (1) · Centre of Postgraduate Medical Education (1) · Copenhagen University Hospital, Rigshospitalet (1) · Erasmus Medical Center (1) · Esbjerg Hospital - University Hospital of Southern Denmark (1) · Federal University of Juiz de Fora (1) · Georgetown University (1) · Gumi Cha Medical Center (1) · Hospital Clinic of Barcelona (1) · Hungarian Institute of Cardiology (1) · Insel Gruppe AG, University Hospital Bern (1)
United States (11) · South Korea (3) · Argentina (2) · Brazil (2) · China (2) · Denmark (2) · Netherlands (2) · Spain (2) · United Kingdom (2) · Hungary (1) · Israel (1) · Poland (1) · Switzerland (1) · Turkey (Türkiye) (1)
Allan Struthers, MD FRCP (1) · Anders Perner, Professor, MD, PhD (1) · Carlos Simon, MD, PhD (1) · Clare Clarke, PhD MCSP (1) · Denise Houston, PhD (1) · Dennis Sullivan, MD (1) · Dr Martin Connolly, MD, FRCP (1) · Du Hyun Ro, MD, PhD (1) · Ewout J Hoorn, MD PhD (1) · Fernando Pagan, MD (1) · Graeme Houston, FRCP FRCR (1) · Jacob George, MRCP MD (1) · Jianfang Ni, bachelor (1) · Joan Trabal, RD, MS (1)
PMID 16260965, PMID 18996225, PMID 20592293, PMID 21084399, PMID 21697501, PMID 23292288, PMID 26384164, PMID 27005892, PMID 27585532, PMID 28936712, PMID 28950424, PMID 28981994, PMID 29035179, PMID 29846604, PMID 29898702, PMID 31438863, PMID 32221675, PMID 32424535, PMID 34862753, PMID 35086483, PMID 35806119, PMID 35963741, PMID 36186800, PMID 36287929, PMID 36364144, PMID 36721961, PMID 37812446, PMID 38224135, PMID 38333911, PMID 39227842, PMID 41789181
2018 (2), 2023 (1), P30AG021332 (1), P30AG024827 (1), U01AG014369 (1)