10 recruiting, 6 completed, 4 unknown, 3 not yet recruiting. 13 Not applicable, 5 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Recruiting 6, Completed 3, Unknown 3, Not yet recruiting 1 |
| Phase 2 | 5 | Recruiting 2, Completed 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Asthma Acute: new trials by email Literature Review of Asthma Acute trials Research Report on Asthma Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulized Ketamine for Severe Asthma Attacks in Children Ketamine (1 mg/kg), Placebo - Asthma Acute, Exacerbation of Allergic Asthma | Phase 2 | Not yet recruiting | Sultan Qaboos University | 60 | 2027-01-01 | 2026-07-27 |
| Rademikibart IV for Acute Asthma and COPD Exacerbation Rademikibart - Asthma Acute, COPD Exacerbation Acute | Phase 2 | Recruiting | Connect Biopharm LLC | 40 | 2026-08-21 | 2026-10-22 |
| Post Exacerbation Asthma Clinic Telecare Intervention to Reduce Recurrent Exacerbations Follow-up in a remote flare-up clinic - Asthma Acute, Asthma Attack | Not applicable | Recruiting | Tel-Aviv Sourasky Medical Center | 220 | 2026-07-01 | 2026-09-24 |
| Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations Nebulized ketamine (0.5 mg/kg in normal saline to a total volume of 5ml) plus standard asthma excaerbationcare, Placebo nebulization (5 mL normal saline) plus standard asthma care - Asthma Acute, Asthma Attack | Phase 2 | Recruiting | Oman Medical Speciality Board | 100 | 2026-05-30 | 2026-10-19 |
| Retrospective Study of Patients with Acute Presentation for Asthma to an Emergency Department in UK (RAPAE) Asthma Acute | Not yet recruiting | Norfolk and Norwich University Hospitals NHS Foundation Trust | 400 | 2025-12-01 | 2025-02-27 | |
| 45th Multicenter Airway Research Collaboration Airsupra - Asthma Acute, Asthma Exacerbation | Phase 4 | Recruiting | Massachusetts General Hospital | 1860 | 2025-11-07 | 2026-04-17 |
| ASMact: Study on Management of Bronchial Asthma Asthma Acute, Asthma Childhood | Recruiting | Meyer Children's Hospital IRCCS | 500 | 2025-11-05 | 2026-02-17 | |
| DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions Adhera Caring Digital Program-Obesity (ACDP-O) - Type 1 Diabetes, T1D | Not applicable | Recruiting | Adhera Health, Inc. | 280 | 2025-10-30 | 2026-06-23 |
| Children's Health, Respiratory Inflammation and Short-term Air Pollution science lesson, PE Lesson - Asthma Acute, Respiratory | Not applicable | Recruiting | Queen Mary University of London | 330 | 2025-10-20 | 2026-06-15 |
| Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations Montelukast Oral Granules - Asthma; Status, Asthma in Children | Phase 2 | Withdrawn | Vanderbilt University Medical Center | 2025-09-01 | 2024-11-18 | |
| Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study Observational - Allergic Asthma, Thunderstorm Asthma | Not applicable | Recruiting | University of Melbourne | 530 | 2025-08-27 | 2026-05-06 |
| Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma) Rademikibart in prefilled syringe, Matching placebo in prefilled syringe - Asthma Acute | Phase 2 | Completed | Connect Biopharm LLC | 160 | 2025-08-08 | 2026-09-16 |
| Immune Nutrition in Pediatric Respiratory Allergy AllergySTOP, Placebo - Asthma Acute, Allergic Rhinitis | Not applicable | Completed | Federico II University | 40 | 2025-06-01 | 2026-02-17 |
| Study on Acupuncture Treatment of Chronic Airway Diseases(Asthma and Chronic Obstructive Pulmonary Disease) Acupuncture, Sham Acupuncture - COPD Exacerbation Acute, Asthma Acute | Not applicable | Not yet recruiting | Henan University of Traditional Chinese Medicine | 576 | 2025-03-01 | 2025-03-11 |
| Use of Dupilumab in Asthma in Real-world Setting Asthma Acute | Active not recruiting | Hospices Civils de Lyon | 35000 | 2025-01-02 | 2026-06-09 | |
| Remote Patient Monitoring Solution for Chronic Respiratory Disease Management AeviceMD device, Standard care - Asthma, Asthma Attack | Not applicable | Recruiting | SingHealth Polyclinics | 180 | 2024-05-01 | 2025-05-15 |
| Comparison Of Efficacy Of Hydrocortisone And Methyl Prednisolone In Acute Severe Asthma Methylprednisolone, - Asthma Acute | Unknown | University of Karachi | 60 | 2023-11-26 | 2023-12-15 | |
| Characterization of Natural Killer Cells in Severe Asthma Patients in Comparison With Control Subjects blood sample - Asthma Acute | Not applicable | Recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 448 | 2023-09-07 | 2025-04-25 |
| Checklists Resuscitation Emergency Department Emergency Manual - Shortness of Breath, Chest Pain | Not applicable | Unknown | Region Skane | 2000 | 2023-09-01 | 2022-12-14 |
| The Effect of Nebulization Positions in Asthmatic Children A Randomized Controlled Study - Asthma Attack, Asthma in Children | Not applicable | Completed | Istanbul University - Cerrahpasa | 86 | 2019-10-15 | 2022-04-08 |
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Asthma (12) · Chest Pain (2) · Hypersensitivity (2) · Abdominal Pain (1) · Bradycardia (1) · Burns (1) · Caregiver Burden (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Ketoacidosis (1) · Disease (1) · Dyspnea (1) · Emergencies (1) · Fever (1) · Heart Arrest (1) · Motor Activity (1)
Immune System Diseases (14) · Respiratory Tract Diseases (14) · Hypersensitivity, Immediate (13) · Lung Diseases (13) · Respiratory Hypersensitivity (13) · Bronchial Diseases (12) · Hypersensitivity (12) · Lung Diseases, Obstructive (12) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (4) · Otorhinolaryngologic Diseases (3) · Signs and Symptoms (3) · Behavior (2) · Diabetes Mellitus (2) · Disease Attributes (2)
Continuous Positive Airway Pressure (2) · Acupuncture Therapy (1) · Aminophylline (1) · Blood Specimen Collection (1) · Health Services Needs and Demand (1) · Hydrocortisone (1) · Ipratropium (1) · Ketamine (1) · Magnesium Sulfate (1) · Methylprednisolone (1) · Oxygen (1) · Saline Solution (1) · Standard of Care (1) · montelukast (1)
Connect Biopharm LLC (2) · Adhera Health, Inc. (1) · Federico II University (1) · Henan University of Traditional Chinese Medicine (1) · Hospices Civils de Lyon (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Istanbul University - Cerrahpasa (1) · Massachusetts General Hospital (1) · Meyer Children's Hospital IRCCS (1) · National Institute of Respiratory Diseases, Mexico (1) · Norfolk and Norwich University Hospitals NHS Foundation Trust (1) · Oman Medical Speciality Board (1) · Queen Mary University of London (1) · Region Skane (1) · SingHealth Polyclinics (1)
United States (5) · United Kingdom (3) · Australia (2) · France (2) · Italy (2) · Oman (2) · Argentina (1) · Brazil (1) · Georgia (1) · Israel (1) · Mexico (1) · Pakistan (1) · Serbia (1) · Singapore (1) · Spain (1)
Abigail Whitehouse, PhD, MD (1) · Andrew Wilson (1) · Dirceu Costa (1) · Donald H Arnold, MD, MPH (1) · Edwin Lampugnani, PhD (1) · Eric Dryver, MD (1) · Fay Johnston, PhD (1) · Frank Thien, MD PhD (1) · James Scales, PhD (1) · Janet Davies, PhD (1) · Jo A Douglass, MD (1) · Jose Luis Carrillo Alduenda (1) · Mabel QH Leow, PhD (1)
PMID 15475599, PMID 17050561, PMID 20930966, PMID 21493723, PMID 28639856, PMID 37848292, PMID 39194097, PMID 42202393, PMID 42517050