3 completed, 3 terminated, 2 unknown. 8 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 3, Terminated 3, Unknown 2 |
| Phase 2 | 2 | Completed 2 |
Follow Asthenia: new trials by email Literature Review of Asthenia trials Research Report on Asthenia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Clinical Efficacy and Safety of Nuvastatic in Cancer Asthenia Nuvastatic TM (C5OSEW5050ESA) 1000 mg - Asthenia, Cancer | Phase 2 / Phase 3 | Completed | Natureceuticals Sdn Bhd | 110 | 2017-09-02 | 2020-09-16 |
| Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia Dexamfetamine sulphate, placebo - Glioma | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 58 | 2013-04-01 | 2016-09-15 |
| Clinical Trial to Evaluate Short-term Efficacy of Palliative Methylphenidate in Asthenia in Advanced Cancer Patients methylphenidate, placebo - Asthenia | Phase 3 | Terminated | Clinica Universidad de Navarra, Universidad de Navarra | 100 | 2012-01-01 | 2017-05-09 |
| A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease Droxidopa, Placebo - Orthostatic Hypotension, Parkinson's Disease | Phase 3 | Completed | Chelsea Therapeutics | 225 | 2010-06-01 | 2014-05-20 |
| Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms Coenzyme Q10, Placebo - Pain, Weakness | Phase 2 / Phase 3 | Completed | Catherine Buettner | 68 | 2009-12-01 | 2017-01-23 |
| A Randomised Controlled Trial of Family Mediated Exercises (FAME) Following Stroke Family Mediated Exercise Therapy - Weakness, Balance | Phase 3 | Unknown | University of Dublin, Trinity College | 40 | 2008-04-01 | 2008-10-29 |
| Ritalin: Antiasthenic Effect of Methylphenidate (Ritalin) in Palliative Care in Cancer Patients methylphenidate, placebo comparator - Asthenia, Neoplasms | Phase 3 | Terminated | University Hospital, Grenoble | 39 | 2007-01-01 | 2009-12-07 |
| Modafinil to Treat Fatigue in Post-Polio Syndrome Modafinil - Postpoliomyelitis Syndrome | Phase 3 | Terminated | National Institute of Neurological Disorders and Stroke (NINDS) | 30 | 2003-08-01 | 2008-08-27 |
Neoplasms (2) · Pain (2) · Depression (1) · Dizziness (1) · Fatigue (1) · Glioma (1) · Hypotension, Orthostatic (1) · Motor Activity (1) · Muscle Cramp (1) · Muscle Weakness (1) · Myalgia (1) · Myositis, Inclusion Body (1) · Neck Pain (1) · Parkinson Disease (1)
Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (8) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Behavior (2) · Central Nervous System Diseases (2) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Neurodegenerative Diseases (2) · Neuromuscular Diseases (2) · Apnea (1) · Autonomic Nervous System Diseases (1) · Basal Ganglia Diseases (1) · Behavioral Symptoms (1) · Brain Diseases (1)
Methylphenidate (2) · Droxidopa (1) · Exercise (1) · Mannitol (1) · Modafinil (1) · Sugars (1) · coenzyme Q10 (1)
Assistance Publique - Hôpitaux de Paris (1) · Catherine Buettner (1) · Chelsea Therapeutics (1) · Clinica Universidad de Navarra, Universidad de Navarra (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Natureceuticals Sdn Bhd (1) · University Hospital, Grenoble (1) · University of Dublin, Trinity College (1)
United States (3) · France (2) · India (1) · Ireland (1) · Spain (1)
Carlos Centeno Cortes, MD, Phd (1) · Catherine Buettner, MD, MPH (1) · Emma Stokes, PhD (1) · Ghanashyam Biswas, PHD (1) · Guillemette Laval, M.D., Ph.D. (1) · Lawrence A. Hewitt, Ph.D. (1) · Robert Hauser, M.D. (1) · Tara Cusack, PhD (1) · William Schwieterman, M.D. (1)
PMID 18570643, PMID 24326693, PMID 27538531, PMID 28494751, PMID 30003579, PMID 38710920
2008 (1), K23AR055664 (1)