2060 completed, 468 unknown, 346 recruiting, 238 not yet recruiting. 2720 Not applicable, 136 Phase 2, 67 Phase 4, 59 Phase 1, 49 Phase 3.
Follow Anxiety: new trials by email Literature Review of Anxiety trials Research Report on Anxiety
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco INNOV5 Integrated Mental Health Program, Enhanced Treatment as Usual (TAU+) - Depression in Adolescence, Depression in Adults | Not applicable | Not yet recruiting | Swiss Medical Academy Maroc | 146 | 2028-03-01 | 2025-12-02 |
| Simulation-Based Patient Education to Address Radiotherapy-Related Anxiety in Cancer Patients (ARAISE) Simulation-Based Patient Education - Neoplasms, Anxiety | Not applicable | Not yet recruiting | University Medical Center Goettingen | 144 | 2028-01-01 | 2026-08-11 |
| Mental Health INtervention With Digital APPlications (MIND-APP): Randomized Controlled Researcher Blinded Trial Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps Tankevirus, Grubl, Placebo Application - Anxiety, Depression | Not applicable | Not yet recruiting | University Hospital, Akershus | 1000 | 2027-08-15 | 2026-06-04 |
| Virtual Intervention for Behavioral Health in Emerging Adults; "VIBE in the Parks" "VIBE in the Parks", Digital Control - Anxiety, Depression | Not applicable | Not yet recruiting | University of Illinois at Chicago | 268 | 2027-07-01 | 2026-04-23 |
| The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms Safe and Sound Protocol, Control - Anxiety, Depression | Not applicable | Not yet recruiting | HealthPartners Institute | 120 | 2027-06-01 | 2026-10-20 |
| Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial UJI Online Transdiagnostic Protocol, UJI On Line Transdiagnostic Hibrid Protocol - Emotional Disorders, Anxiety | Not applicable | Not yet recruiting | Universitat Jaume I | 366 | 2027-05-01 | 2026-05-27 |
| Virtual Communication in the Hospital: Impact on Patients and Surrogates VCHIPS - Communication, Anxiety | Not applicable | Withdrawn | Indiana University | 2027-03-31 | 2026-04-22 | |
| Community Health Worker Implementation of Transdiagnostic Evidence-based Mental Health Intervention for Spanish-speaking Latine Parents Common Elements Treatment Approach (CETA) - Depression, Anxiety | Not applicable | Not yet recruiting | University of Illinois at Chicago | 52 | 2027-02-01 | 2026-02-05 |
| Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message - Psychosis, Anxiety | Not applicable | Not yet recruiting | Mclean Hospital | 10 | 2027-01-15 | 2026-10-05 |
| Immersive VR to Reduce Stress, Anxiety, and Pain During PICC/Midline Placement Immersive Virtual Reality, Peripherally Inserted Central Catheter (PICC), Mepivacaine 2% Injection - Vasoconstriction, Biomarkers | Not applicable | Not yet recruiting | diana garcia | 202 | 2027-01-15 | 2026-07-10 |
| Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) PARTNER-MH, Educational Brochure - Diagnoses of Depression, Anxiety | Not applicable | Not yet recruiting | VA Office of Research and Development | 268 | 2027-01-04 | 2026-06-16 |
| An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma Cognitive Processing Therapy - Post-Traumatic Stress Disorder, Chronic, Depressed Mood | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 25 | 2027-01-01 | 2026-10-15 |
| Music Interventions During Wide-Awake Hand Surgery Standardized Relaxation Music, Personal Choice of Music - Anxiety, Surgery | Not applicable | Recruiting | University of Wisconsin, Madison | 170 | 2027-01-01 | 2026-09-29 |
| The Role of Virtual Reality During Regional Anesthesia Virtual Reality with Oculus Go headset - Anxiety, Pain | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 80 | 2027-01-01 | 2026-08-14 |
| Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan Virtual Reality - Cutaneous Leishmaniasis, Pain | Not applicable | Not yet recruiting | Stanford University | 15 | 2027-01-01 | 2026-10-05 |
| Implementation of a Just-In-Time Adaptive Intervention for Adolescent Anxiety Just-In-Time Adaptive Intervention for Adolescent Anxiety - Anxiety, Anxiety Disorders | Not applicable | Not yet recruiting | Trustees of Dartmouth College | 50 | 2027-01-01 | 2026-04-02 |
| Quantifying Multi-step Avoidance in Anxiety Behavioral Tasks with imaging - Anxiety, Anxiety Disorders | Not applicable | Not yet recruiting | Emory University | 163 | 2027-01-01 | 2026-10-05 |
| Personalizing Mental Health Treatment for Youth and Families Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT), Cultural Formulation Interview, Modular Approach to Therapy for Children - Anxiety, Traumatic Stress | Not applicable | Not yet recruiting | University of Oregon | 64 | 2027-01-01 | 2026-02-20 |
| Comparative Effects of Four Brief Breathwork and Mindfulness Interventions on Anxiety and Psychological Flexibility: A 4-Arm RCT Box Breathing, Cyclic Sighing, Mindfulness AH Exhalation - Anxiety, Psychological Flexibility | Not applicable | Not yet recruiting | Valencian International University (VIU) | 240 | 2027-01-01 | 2026-06-04 |
| Pre-operative Interventional Paramedical Consultation: What About the Implantable Device? Paramedical consultation - Anxiety, Paramedical Consultation | Not applicable | Recruiting | University Hospital, Grenoble | 150 | 2027-01-01 | 2026-10-02 |
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PMID 16717171, PMID 2748771, PMID 26969158, PMID 29624026, PMID 37199436, PMID 38569683, PMID 40243391, PMID 42714910, PMID 11556271, PMID 12296495, PMID 16367493, PMID 16640481, PMID 18042300, PMID 20089179, PMID 20461783, PMID 23469262, PMID 24733354, PMID 25641687, PMID 28013354, PMID 28487349, PMID 29413142, PMID 29793970, PMID 30702436, PMID 30957867, PMID 31237569, PMID 3170753, PMID 32618627, PMID 32663929, PMID 33319916, PMID 33626029, PMID 3397865, PMID 35397973, PMID 35722590, PMID 35723668, PMID 37278621, PMID 38916221, PMID 42802645, PMID 10259963, PMID 10267267, PMID 10381705, PMID 10489826, PMID 10578798, PMID 10661603, PMID 10668003, PMID 10784636, PMID 10826123, PMID 10875713, PMID 10883553, PMID 10901408, PMID 10960931
2023 (5), P50MH122351 (5), 2018 (4), 2019 (4), 2017 (3), 2025 (3), 2014 (2), 5UL1TR001420-03 (2), K08MH112878 (2), P30CA013330 (2), P50MH115837 (2), R01MD012230 (2), R33AT010125 (2), R34MH100468 (2), R34MH134937 (2)