17 completed, 4 unknown, 2 not yet recruiting, 2 recruiting. 18 Not applicable, 2 Early Phase 1, 2 Phase 4, 1 Phase 2, 1 Phase 3.
Follow Ankle Fracture: new trials by email Literature Review of Ankle Fracture trials Research Report on Ankle Fracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Virtual Ankle Rehabilitation (EVAR): Acceptability EVAR, EMADE - Ankle Fracture | Not applicable | Not yet recruiting | University of Nottingham | 30 | 2026-07-22 | 2026-08-07 |
| Physical Recovery During Bracing After Ankle Fracture (Re-BAF) Ankle stirrup, Foot-ankle brace - Ankle Fracture, Recovery | Not applicable | Recruiting | Odense University Hospital | 280 | 2026-06-01 | 2026-10-16 |
| Bracing After Ankle Fracture ankel stirrup, Foot-ankel brace (walker) - Ankle Fracture, Rehabilitation | Not applicable | Recruiting | Odense University Hospital | 1400 | 2026-04-23 | 2026-04-29 |
| Compression Therapy for Swelling Management Following Ankle Injury Compression sleeve - Ankle Fracture, Ankle Arthrodesis | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-04-01 | 2025-01-24 |
| Telerehabilitation in Patients With Ankle Fracture Tele-rehabilitation, Hospital rehabilitation - Ankle Fracture | Not applicable | Completed | Instituto Mexicano del Seguro Social | 200 | 2025-02-18 | 2026-10-27 |
| Ankle Fracture Tourniquet Utilization Tourniquet, No Tourniquet - Ankle Fracture | Not applicable | Enrolling by invitation | Alex Demers | 100 | 2024-11-24 | 2026-02-17 |
| Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization Early Weight bearing + Cam Boot, Non-Weight Bearing + Cam Boot - Ankle Fracture | Not applicable | Completed | NYU Langone Health | 107 | 2017-09-01 | 2023-11-03 |
| Is Deltoid Ligament Repair for Ankle Fracture Necessary? Repair Deltoid Tendon, Ankle Fracture Without Deltoid Tendon Repair - Ankle Fracture | Not applicable | Withdrawn | Mayo Clinic | 2016-05-01 | 2018-08-22 | |
| Manual Therapy After Ankle/Hindfoot Fractures Manual Therapy Group, Control Group - Ankle Fracture, Calcaneus Fracture | Not applicable | Completed | Intermountain Health Care, Inc. | 72 | 2015-11-01 | 2019-03-13 |
| NSAIDS Versus Opioids in Acute SER II Ankle Fractures Ibuprofen, Acetaminophen/hydrocodone - Ankle Fracture | Early Phase 1 | Completed | University of California, Davis | 1 | 2015-01-01 | 2017-07-14 |
| Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF) Liposomal Bupivacaine with Bupivacaine - Ankle Fracture | Phase 3 | Completed | Jamaica Hospital Medical Center | 84 | 2014-12-01 | 2017-10-20 |
| Insole Sensor to Determine Optimal Limb Loading in the Rehabilitation of Ankle Fractures Ankle Fracture | Completed | University of Utah | 38 | 2014-08-01 | 2017-10-26 | |
| Exparel and Ankle Surgery Exparel - Ankle Fracture | Not applicable | Completed | Rutgers, The State University of New Jersey | 4 | 2014-02-01 | 2016-09-23 |
| Early Weightbearing Versus Non-weightbearing After Operative Treatment of an Ankle Fracture Early weightbearing, Non-weightbearing - Ankle Fracture, Rehabilitation | Not applicable | Unknown | Hallym University Medical Center | 192 | 2014-01-01 | 2015-10-09 |
| Triage Nurse Initiated Radiographs According to OAR Triage nurses applying the OAR - Ankle Fracture | Not applicable | Unknown | Vancouver Coastal Health | 142 | 2012-07-01 | 2012-09-12 |
| Study on Wood-plastic Composite for Circumferential Casting limb casting/splinting - Bone Fracture, Radius Fracture | Not applicable | Completed | Onbone Oy | 97 | 2011-12-01 | 2017-07-05 |
| Aspiration for Pain Relief Following Ankle Fracture Ankle Aspiration, Ankle aspiration Standard Anterolateral - Ankle Fracture | Not applicable | Completed | Mayo Clinic | 130 | 2011-09-01 | 2015-07-17 |
| The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture vitamin c, placebo - Ankle Fracture | Not applicable | Unknown | Rabin Medical Center | 100 | 2011-04-01 | 2011-04-19 |
| Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study Nonsurgical, Surgical - Ankle Fracture, Malleolus Fracture | Not applicable | Unknown | University of Tennessee | 30 | 2011-04-01 | 2018-11-28 |
| Ankle Fracture Treatment in the Elderly Fracture union - Ankle Fracture | Completed | University of Florida | 118 | 2011-03-01 | 2017-10-03 |
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Ankle Fractures (27) · Fractures, Bone (3) · Motor Activity (2) · Acute Lung Injury (1) · Ankle Injuries (1) · Complex Regional Pain Syndromes (1) · Pain (1) · Radius Fractures (1)
Leg Injuries (27) · Wounds and Injuries (27) · Ankle Injuries (26) · Fractures, Bone (24) · Behavior (2) · Arm Injuries (1) · Autonomic Nervous System Diseases (1) · Forearm Injuries (1) · Lung Diseases (1) · Lung Injury (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Neuromuscular Diseases (1) · Pathological Conditions, Signs and Symptoms (1) · Peripheral Nervous System Diseases (1)
Ascorbic Acid (1) · Braces (1) · Bupivacaine (1) · Control Groups (1) · High-Energy Shock Waves (1) · Hospitals, Rehabilitation (1) · Ibuprofen (1) · Periodontal Debridement (1) · Surgical Procedures, Operative (1) · Telerehabilitation (1) · Tourniquets (1) · Walkers (1) · oxycodone-acetaminophen (1)
Mayo Clinic (2) · Odense University Hospital (2) · AO Clinical Investigation and Publishing Documentation (1) · Alex Demers (1) · Hadassah Medical Organization (1) · Hallym University Medical Center (1) · Instituto Mexicano del Seguro Social (1) · Intermountain Health Care, Inc. (1) · Jamaica Hospital Medical Center (1) · NYU Langone Health (1) · National Police Hospital (1) · Nova Scotia Health Authority (1) · Onbone Oy (1) · Rabin Medical Center (1) · Rhode Island Hospital (1)
United States (13) · Canada (4) · Denmark (2) · Finland (2) · Israel (2) · South Korea (2) · Brazil (1) · Faroe Islands (1) · Mexico (1) · United Kingdom (1)
Alex Demers, MD (1) · Anders Holsgaard-Larsen, PhD (1) · Ben A Marson, FRCS, PhD (1) · Ben J Ollivere, FRCS, MD. (1) · Bjarke Viberg, Phd (1) · David Rothberg, M.D. (1) · Dirk W Kiner, M.D. (1) · Glenn G Shi (1) · Hannu T Aro, MD, PhD (1) · Hyong Nyun Kim, MD, PhD (1) · Jean Daniel Eloy, MD (1) · Jung Ho Noh, M.D., Ph.D. (1) · Kalia K Sadasivan, M.D. (1) · Kathy K Boutis, MD (1) · Leonid Kandel, MD (1)
PMID 12143985, PMID 15563389, PMID 15566705, PMID 16596889, PMID 17545357, PMID 19267907, PMID 21075372, PMID 21959254, PMID 22222143, PMID 25059747, PMID 25373046, PMID 34251882, PMID 41978451