4 completed, 2 recruiting, 2 terminated, 2 unknown. 3 Phase 1, 3 Phase 4, 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 2, Unknown 1 |
| Phase 4 | 3 | Completed 2, Recruiting 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Analgesics, Non-Narcotic: new trials by email Literature Review of Analgesics, Non-Narcotic trials Research Report on Analgesics, Non-Narcotic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulized Ketamine for the Treatment of Major Depressive Disorder nebulized ketamine, nebulized midazolam - Severe Depression, Moderate Depression | Phase 3 | Recruiting | Theresa Jacob, PhD, MPH | 40 | 2024-10-16 | 2026-04-24 |
| Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression VTS-K - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Theresa Jacob, PhD, MPH | 15 | 2022-12-06 | 2026-04-21 |
| Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study Dexmedetomidine 0.004 MG/ML [Precedex], Opioids - Analgesia, Analgesics, Opioid | Phase 3 | Completed | St. Justine's Hospital | 42 | 2022-03-15 | 2023-05-09 |
| Telehealth Delivered Physical Rehabilitation for an Ankle Sprain Telehealth Protocol, Usual Care - Ankle Sprains, Telerehabilitation | Not applicable | Completed | Kyle Kosik | 21 | 2021-01-01 | 2025-07-28 |
| Lidocaine and Magnesium and Ketamine in Gynecological Surgery lidocaine-magnesium infusion, lidocaine-ketamine infusion, lidocaine infusion - Pain, Postoperative, Pain, Acute | Not applicable | Unknown | Aretaieion University Hospital | 90 | 2020-11-14 | 2022-10-27 |
| Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM CYNK001-IV, CYNK001-IT - Astrocytoma, Grade IV, Giant Cell Glioblastoma | Phase 1 | Terminated | Celularity Incorporated | 3 | 2020-10-01 | 2022-08-10 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma CYNK-001 - Multiple Myeloma, Neoplasm, Plasma Cell | Phase 1 | Unknown | Celularity Incorporated | 29 | 2020-05-12 | 2023-02-16 |
| Natural Killer Cell (CYNK-001) Infusions in Adults with AML CYNK-001 - Leukemia, Leukemia, Myeloid | Phase 1 | Terminated | Celularity Incorporated | 27 | 2020-03-12 | 2024-12-12 |
| Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients Dexmedetomidine Hydrochloride Group - Delirium, Cognitive Dysfunction | Phase 4 | Recruiting | Sunnybrook Health Sciences Centre | 2400 | 2019-12-01 | 2025-12-01 |
| Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy Abdominal wall block with liposomal bupivicaine - Pain, Postoperative, Analgesics, Opioid | Phase 4 | Completed | University of California, Los Angeles | 146 | 2018-01-01 | 2022-01-10 |
Acute Pain (2) · Agnosia (2) · Depression (2) · Hematologic Diseases (2) · Neoplasm, Residual (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Pain, Postoperative (2) · Ankle Injuries (1) · Blood Protein Disorders (1) · Cardiovascular Diseases (1) · Chronic Pain (1) · Cognition Disorders (1) · Cognitive Dysfunction (1) · Confusion (1)
Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Pathologic Processes (4) · Behavior (3) · Nervous System Diseases (3) · Behavioral Symptoms (2) · Hemic and Lymphatic Diseases (2) · Neoplastic Processes (2) · Neurobehavioral Manifestations (2) · Pain (2) · Perceptual Disorders (2) · Postoperative Complications (2) · Astrocytoma (1) · Depressive Disorder (1)
Dexmedetomidine (2) · Ketamine (2) · Analgesics, Opioid (1) · Aspirin (1) · Midazolam (1)
Celularity Incorporated (3) · Theresa Jacob, PhD, MPH (2) · Aretaieion University Hospital (1) · Kyle Kosik (1) · St. Justine's Hospital (1) · Sunnybrook Health Sciences Centre (1) · University of California, Los Angeles (1)
United States (7) · Canada (2) · Greece (1)
Theresa Jacob, PhD, MPH (2) · Adrian Kilcoyne, MD (1) · Christina Lamontagne (1) · Kassiani Theodoraki, PhD, DESA (1) · Kyle Kosik, Ph.D. (1) · Sharmila Koppisetti, M.D (1) · Sharmila Koppisetti, MD (1) · Siamak Rahman, MD (1) · Stephen Choi, MD,MSc,FRCPC (1)