11 completed, 4 unknown, 3 active not recruiting, 2 recruiting. 22 Phase 3, 11 Phase 2.
Follow Alcohol Drinking: new trials by email Literature Review of Alcohol Drinking trials Research Report on Alcohol Drinking
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease MINDSET, Usual Care - Tobacco Smoking, Alcohol-Related Disorders | Phase 3 | Recruiting | VA Office of Research and Development | 270 | 2025-10-01 | 2025-12-31 |
| Effects of Ketone Supplement and Alcohol on Brain Metabolism Kenetik, Alcohol beverage - Ketosis, Alcohol Drinking | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 60 | 2025-05-13 | 2026-10-14 |
| Effect of Nutritional Ketosis on Alcohol Metabolism Ketone Supplement, Control Diet, Ketogenic diet - Ketoses, Metabolic, Ketogenic Dieting | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 23 | 2024-02-29 | 2026-04-07 |
| Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers Ketone Supplement, Alcohol Beverage - Alcohol Drinking | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 10 | 2022-10-20 | 2026-08-06 |
| Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate", FDG - Alcohol Use Disorder (AUD), Alcohol Drinking | Phase 2 / Phase 3 | Enrolling by invitation | University of Pennsylvania | 20 | 2021-11-01 | 2026-03-30 |
| Transcendental Meditation and PTSD TM, PCT - Ptsd, Depressive Symptoms | Phase 3 | Unknown | David Lynch Foundation | 450 | 2021-10-01 | 2021-04-22 |
| Ketone Ester Intervention in Alcohol Use Disorder Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate", Isocaloric dextrose placebo, Alcohol drinks - Alcohol Drinking, Alcohol Use Disorder | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 20 | 2021-04-05 | 2026-02-09 |
| Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV) Varenicline, Cytisine, Nicotine Replacement Therapy - HIV Infection, Alcohol Use | Phase 2 / Phase 3 | Completed | Boston Medical Center | 400 | 2017-07-19 | 2020-12-17 |
| Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge - Nicotine Dependence, Tobacco Use | Phase 3 | Unknown | Mark Vander Weg | 411 | 2013-07-01 | 2017-07-11 |
| Kudzu Effects on Brain Ethanol Levels: Proton Spectroscopy Assessment Kudzu extract - Alcohol Consumption, Cerebral Blood Flow | Phase 2 / Phase 3 | Withdrawn | Mclean Hospital | 2012-11-01 | 2015-10-27 | |
| Efficacy of Gabapentin in Alcohol Dependency Treatment Gabapentin 300mg, Placebo oral capsule - Alcohol Drinking, Heavy Drinking | Phase 3 | Completed | Chulalongkorn University | 112 | 2012-01-01 | 2017-09-06 |
| Emerging Adults Who Use Alcohol and Marijuana motivational intervention, health education - Alcohol Use, Marijuana Use | Phase 3 | Completed | Butler Hospital | 566 | 2012-01-01 | 2017-09-18 |
| Implementing Evidence-Based Mental Health Practices in Primary Care brief alcohol intervention, standard care - Alcohol Consumption | Phase 3 | Completed | VA Office of Research and Development | 167 | 2009-12-01 | 2017-01-02 |
| The Role of the Glutamatergic System in the Extinction of Conditioned Reinforcement Processes D-cycloserine, Placebo - Alcohol Drinking | Phase 2 / Phase 3 | Unknown | Central Institute of Mental Health, Mannheim | 80 | 2009-03-01 | 2011-11-28 |
| Promoting Self-Change From Alcohol Problems: Mechanisms of Change in a Community-Based Intervention Promoting Self-Change with Ads - Alcohol Drinking, Alcohol Abuse | Phase 3 | Completed | Nova Southeastern University | 283 | 2008-03-01 | 2010-12-14 |
| Mindfulness and Cancer Mamma - Clinical Trial MBSR Among Women Operated for Breast Cancer mindfulness based stress reduction (MBSR) - Breast Cancer | Phase 2 / Phase 3 | Completed | Danish Cancer Society | 336 | 2008-03-01 | 2015-06-30 |
| Medication and Counseling for Controlled Drinking (Project SMART) Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy - Alcohol-related Disorders, Alcohol Drinking | Phase 3 | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 200 | 2006-04-01 | 2013-05-01 |
| Addiction Health Evaluation And Disease Management (AHEAD) Study Chronic Disease Management for substance abuse, Standard care - Alcohol Dependence, Alcoholism | Phase 3 | Completed | Boston Medical Center | 569 | 2006-04-01 | 2014-10-02 |
| Brief Counseling to Reduce Injuries Among Emergency Department Patients Who Report Alcohol and Substance Use brief counseling - Alcohol Drinking, Marijuana Smoking | Phase 2 / Phase 3 | Unknown | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 554 | 2003-12-01 | 2008-10-08 |
| Personality-targeted Interventions for Adolescent Alcohol Misuse PRE-Venture: Personality Risk Education - Alcohol Abuse, Drug Abuse | Phase 2 / Phase 3 | Completed | King's College London | 710 | 2003-11-01 | 2011-06-27 |
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Alcoholism (8) · Depression (4) · Smoking (3) · Substance-Related Disorders (3) · Alcohol-Related Disorders (2) · Anxiety Disorders (2) · Ketosis (2) · Patient Acceptance of Health Care (2) · Tobacco Use (2) · Alcoholic Intoxication (1) · Antisocial Personality Disorder (1) · Behavior (1) · Behavior, Addictive (1) · Binge Drinking (1)
Drinking Behavior (22) · Behavior (21) · Mental Disorders (15) · Chemically-Induced Disorders (12) · Substance-Related Disorders (10) · Alcohol-Related Disorders (8) · Pathological Conditions, Signs and Symptoms (5) · Behavioral Symptoms (4) · Pathologic Processes (4) · Disease Attributes (3) · Health Behavior (3) · Acid-Base Imbalance (2) · Acidosis (2) · Communicable Diseases (2) · Genital Diseases (2)
Ethanol (6) · Standard of Care (2) · Varenicline (2) · 1,3-butylene glycol (1) · Bupropion (1) · Crisis Intervention (1) · Cycloserine (1) · Diet, Ketogenic (1) · Educational Status (1) · Fluorodeoxyglucose F18 (1) · Gabapentin (1) · Methods (1) · Mindfulness-Based Stress Reduction (1) · Motivational Interviewing (1) · Naloxone (1)
University of Pennsylvania (5) · Boston Medical Center (3) · Butler Hospital (2) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (2) · VA Office of Research and Development (2) · Central Institute of Mental Health, Mannheim (1) · Chulalongkorn University (1) · Danish Cancer Society (1) · David Lynch Foundation (1) · King's College London (1) · Mark Vander Weg (1) · Mclean Hospital (1) · Nova Southeastern University (1)
United States (14) · Denmark (1) · Germany (1) · Russia (1) · Thailand (1) · United Kingdom (1)
Corinde E Wiers, Ph.D. (2) · Corinde Wiers, Ph.D. (2) · Christoffer Johansen, M.D., Ph.D. (1) · Corinde Wiers, PhD (1) · Falk Kiefer, Professor (1) · Henry Kranzler, MD (1) · Janette Baird, PhD (1) · Jeffrey H Samet, MA, MA, MPH (1) · Jennifer S Funderburk, PhD (1) · Jon Morgenstern, PhD (1) · Julie Christina Gass, PhD (1) · Kyle Kampman, MD (1) · Linda C Sobell, Ph.D. (1) · Mark W. Vander Weg, Ph.D. (1) · Michael A Cucciare, PhD (1)
PMID 15908848, PMID 17283347, PMID 19515290, PMID 20048226, PMID 20402990, PMID 20732631, PMID 20869813, PMID 21278321, PMID 21292243, PMID 22388536, PMID 22458289, PMID 22592966, PMID 22854293, PMID 23218847, PMID 23265707, PMID 23276300, PMID 23282113, PMID 23490572, PMID 23786513, PMID 24045740, PMID 25086446, PMID 25219686, PMID 25222129, PMID 25524751, PMID 25752972, PMID 25915689, PMID 28622099, PMID 30461442, PMID 30865304, PMID 31908107, PMID 35930287, PMID 37142273
P60AA013759 (2), R21AA031088 (2), R00AA026892 (1), R01AA014495 (1), R21AA017136 (1), U01AA020780 (1)