55 completed, 9 recruiting, 8 unknown, 5 active not recruiting. 89 Phase 2, 15 Phase 1, 11 Phase 3.
Follow Alcohol Drinking: new trials by email Literature Review of Alcohol Drinking trials Research Report on Alcohol Drinking
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study Brexanolone - Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD) | Phase 2 | Not yet recruiting | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 40 | 2027-01-15 | 2026-09-21 |
| Precision Microbiota Interventions for Senoreduction Trial Limosilactobacillus reuteri, Blueberry extract - HIV Infections, Alcohol Drinking | Phase 1 / Phase 2 | Recruiting | Louisiana State University Health Sciences Center in New Orleans | 160 | 2026-09-01 | 2026-10-29 |
| Probenecid Administration for Alcohol Craving and Consumption Probenecid Oral Tablet, Placebo Oral Tablet - Alcohol Use Disorder (AUD), Alcohol Consumption | Phase 2 | Recruiting | Brown University | 120 | 2026-03-14 | 2026-03-17 |
| Effects of Ketone Supplement and Alcohol on Brain Metabolism Kenetik, Alcohol beverage - Ketosis, Alcohol Drinking | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 60 | 2025-05-13 | 2026-10-14 |
| Rapid BAC Reduction with Nutraceutical Blend Study Supplement, Placebo - Alcohol Consumption, Alcohol | Phase 2 | Not yet recruiting | Medical Life Care Planners, LLC | 35 | 2024-12-01 | 2024-12-09 |
| Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder Sunobinop, Placebo to match sunobinop - Alcohol Use Disorder | Phase 2 | Completed | Knoa Pharma LLC | 209 | 2024-10-14 | 2026-06-05 |
| Evaluating Cannabidiol as a Novel Anticraving Medication for Alcohol Use Disorder Oral solution - Alcohol Use Disorder | Phase 2 | Active not recruiting | Centre for Addiction and Mental Health | 36 | 2024-08-16 | 2026-11-02 |
| Metabolic Changes Induced by NMN in Healthy Subjects With Acute Binge Drink β-nicotinamide Mononucleotide, Maltodextrin - Binge Drinking, Liver Injury | Phase 1 / Phase 2 | Completed | Zhejiang Chinese Medical University | 22 | 2024-05-01 | 2025-04-10 |
| Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD Cognitive Processing Therapy + Relapse Prevention, Relapse Prevention - Posttraumatic Stress Disorder, Alcohol Use Disorder | Phase 2 | Recruiting | Texas A&M University | 200 | 2024-04-01 | 2026-04-24 |
| Effect of Nutritional Ketosis on Alcohol Metabolism Ketone Supplement, Control Diet, Ketogenic diet - Ketoses, Metabolic, Ketogenic Dieting | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 23 | 2024-02-29 | 2026-04-07 |
| Gabapentin to Reduce Alcohol and Improve Viral Load Suppression Gabapentin, Placebo - HIV, Heavy Drinking | Phase 2 | Active not recruiting | Boston Medical Center | 220 | 2023-11-20 | 2026-11-05 |
| Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT Probiotic, Placebo - Microtia, Dysbiosis | Phase 2 | Recruiting | Vanderbilt University Medical Center | 250 | 2023-09-18 | 2026-08-27 |
| Semaglutide Therapy for Alcohol Reduction - Tulsa Semaglutide, Placebo - Alcohol Use Disorder | Phase 2 | Completed | Oklahoma State University Center for Health Sciences | 80 | 2023-07-07 | 2025-12-17 |
| Cannabis' Impact on Alcohol Consumption THC-dominant cannabis, CBD-dominant cannabis, Cannabis placebo - Alcohol Drinking, Cannabis Use | Phase 2 | Recruiting | Brown University | 350 | 2023-03-16 | 2026-10-05 |
| The Brain, the Bug, and the Binge: the Interplay Between Binge Drinking, Gut Microbiota, and Brain Functioning Inulin Intervention, Maltodextrin Intervention - Binge Drinking | Phase 2 | Recruiting | University of Minho | 82 | 2023-02-24 | 2025-07-16 |
| Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers Ketone Supplement, Alcohol Beverage - Alcohol Drinking | Phase 2 / Phase 3 | Active not recruiting | University of Pennsylvania | 10 | 2022-10-20 | 2026-08-06 |
| Personalized Feedback After Alcohol Health Education for Members of Greek Life (GREEK Study) e-checkup to go, Delayed feedback booster - College Student Drinking | Phase 1 / Phase 2 | Unknown | Abby Braitman | 250 | 2022-04-06 | 2023-05-03 |
| Probiotics, Immune Function, and the Brain in Alcohol Consumers Seed DS-01 Daily Synbiotic - Alcohol; Use, Problem | Phase 2 | Completed | Brown University | 32 | 2022-02-24 | 2024-09-19 |
| Does Oxytocin Alter Tolerance to or Motivation for Alcohol Intranasal oxytocin, Intranasal placebo - Alcohol Use Disorder | Phase 2 | Terminated | Indiana University | 6 | 2022-01-16 | 2025-03-04 |
| Human Laboratory Study of ASP8062 for Alcohol Use Disorder ASP8062, Placebo - Alcohol Use Disorder, Alcohol Drinking | Phase 2 | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 60 | 2021-12-13 | 2024-12-03 |
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Alcoholism (38) · Substance-Related Disorders (8) · Binge Drinking (7) · Alcohol-Related Disorders (6) · Behavior, Addictive (6) · HIV Infections (6) · Depression (5) · Alcohol Drinking in College (4) · Alcoholic Intoxication (4) · Stress Disorders, Post-Traumatic (4) · Anxiety Disorders (3) · Drinking Behavior (3) · Inflammation (3) · Marijuana Abuse (3)
Behavior (89) · Drinking Behavior (86) · Mental Disorders (53) · Chemically-Induced Disorders (52) · Substance-Related Disorders (45) · Alcohol-Related Disorders (40) · Pathological Conditions, Signs and Symptoms (9) · Urogenital Diseases (7) · Behavioral Symptoms (6) · Blood-Borne Infections (6) · Communicable Diseases (6) · Compulsive Behavior (6) · Genital Diseases (6) · Immune System Diseases (6)
Ethanol (14) · Naltrexone (8) · Sugars (5) · Varenicline (5) · Baclofen (2) · Bupropion (2) · Crisis Intervention (2) · Gabapentin (2) · Guanfacine (2) · Methods (2) · Tobacco Use Cessation Devices (2) · Topiramate (2) · 1,3-butylene glycol (1) · 1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid (1) · ASP8062 (1)
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (10) · Yale University (9) · Brown University (6) · University of Pennsylvania (6) · Boston Medical Center (5) · Abby Braitman (4) · Mclean Hospital (3) · Centers for Disease Control and Prevention (2) · Centre for Addiction and Mental Health (2) · Medical University of South Carolina (2) · Pharmacotherapies for Alcohol and Substance Use Disorders Alliance (2) · Rhode Island Hospital (2) · The University of Tennessee, Knoxville (2) · University of California, Los Angeles (2) · Arlene Fink Associates (1)
United States (72) · Russia (3) · Canada (2) · Germany (2) · China (1) · Denmark (1) · Portugal (1) · Romania (1) · South Africa (1) · Uganda (1) · United Kingdom (1)
Abby L Braitman, Ph.D. (4) · Sherry A McKee, PhD (3) · Corinde E Wiers, Ph.D. (2) · Corinde Wiers, Ph.D. (2) · Jane Metrik, PhD (2) · Jeffrey H. Samet, MD, MA, MPH (2) · Lorenzo Leggio, M.D. (2) · Sherry McKee, PhD (2) · Suchitra Krishnan-Sarin, Ph.D. (2) · Allen Zweben, PhD (1) · Anka A Vujanovic, Ph.D. (1) · Arlene Fink (1) · Bankole Johnson, DSc,MD,PhD (1) · Bernhard Croissant, MD PhD (1) · Carolina Haass-Koffler, PharmD, PhD (1)
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K01AA023849 (4), P50AA012870 (3), R01AA015596 (2), R01AA022285 (2), R21AA031088 (2), U54AA027989 (2), 1DP5OD019809 (1), K01AA026005 (1), K23AA025399 (1), P01AA019072 (1), P01AA027473 (1), P30GM122734 (1), P60AA013759 (1), R00AA026892 (1), R01AA010522 (1)