7 completed, 6 unknown, 3 recruiting, 2 not yet recruiting. 10 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 4, Not yet recruiting 2, Unknown 2, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Airway Extubation: new trials by email Literature Review of Airway Extubation trials Research Report on Airway Extubation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| One-Hour Positive Pressure Ventilation After a T-Piece Spontaneous Breathing Trial One-hour positive pressure ventilation, Immediate extubation - Airway Extubation, Extubation Failure | Not applicable | Not yet recruiting | Hospital do Coracao | 4000 | 2027-01-01 | 2026-09-22 |
| One-Hour Positive Pressure Ventilation After a Pressure Support Spontaneous Breathing Trial One-hour positive pressure ventilation, Immediate extubation - Airway Extubation, Weaning Mechanical Ventilation | Not applicable | Not yet recruiting | Hospital do Coracao | 4000 | 2027-01-01 | 2026-09-22 |
| Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study Ventilator Weaning, Airway Extubation | Recruiting | Seoul National University Hospital | 50 | 2026-08-11 | 2026-08-18 | |
| Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery Extubation in post-anesthesia care unit (PACU), Extubation in operating room (OR) - Robotic Surgical Procedures, Airway Extubation | Not applicable | Completed | Peking University First Hospital | 218 | 2026-01-24 | 2026-10-21 |
| Inhaled Sedation in Critically Ill Patients Isoflurane, Propofol - Sedation, Airway Extubation | Phase 4 | Recruiting | Instituto de Investigación Hospital Universitario La Paz | 620 | 2025-12-15 | 2026-06-29 |
| Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support Extubation Advisor - Airway Extubation | Not applicable | Recruiting | Ottawa Hospital Research Institute | 200 | 2024-04-22 | 2026-04-22 |
| Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial Reconnection to mechanical ventilation for 1 hour, Direct extubation - Airway Extubation, Ventilator Weaning | Not applicable | Completed | Centro Hospitalar Unimed de Joinville | 60 | 2023-11-02 | 2025-02-17 |
| The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial Traditional online education, Interprofessional education, Clinical protocol - Acute Respiratory Failure, Airway Extubation | Not applicable | Active not recruiting | University of Pittsburgh | 13018 | 2023-03-01 | 2026-05-08 |
| Exploring the Use of Pulse Tissue Doppler in Predicting Extubation Success in Mechanically Ventilated Patients Airway Extubation | Unknown | Affiliated Hospital of Jiangnan University | 200 | 2022-09-01 | 2023-12-08 | |
| Analysis of the Magnetic Tape Bandage on Respiratory Functional Effects. Magnetictape bandage application - Airway Extubation | Not applicable | Unknown | Hospital Universitario Doctor Peset | 31 | 2022-04-01 | 2022-08-25 |
| Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool Extubation Advisor - Airway Extubation | Phase 1 | Completed | Ottawa Hospital Research Institute | 31 | 2021-10-04 | 2025-05-15 |
| ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure Mechanical Ventilator Weaning, Predictive Value of Tests | Unknown | University Hospital, Clermont-Ferrand | 300 | 2021-09-28 | 2023-01-31 | |
| High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients High flow nasal oxygen - Intensive Care, Airway Extubation | Not applicable | Unknown | Hamad Medical Corporation | 450 | 2020-10-17 | 2023-10-31 |
| TCI vs Manually Controlled Infusion of Propofol Target controlled infusion - Anesthesia, Intravenous, Laparotomy | Unknown | Regional Hospital West Jutland | 40 | 2020-05-01 | 2020-02-17 | |
| Relation Between the Volume of Subglottic Secretion and Risk of Extubation Failure in ICU Patients (SEGEX) Airway Extubation, Pneumonia, Bacterial | Unknown | Centre Hospitalier Universitaire de Besancon | 300 | 2019-04-26 | 2019-05-10 | |
| Maximum Expiratory Pressure in Induced Cough as a Predictor of Extubation Failure MEPic - Airway Extubation | Not applicable | Completed | Hospital Nacional Profesor Alejandro Posadas | 80 | 2018-10-01 | 2020-05-04 |
| High Flow Nasal Cannula in Immediately Post Extubation high flow nasal cannula - Airway Extubation, Oxygen Inhalation Therapy | Completed | Hospital Italiano de Buenos Aires | 165 | 2016-12-01 | 2019-03-04 | |
| Diaphragmatic and Pulmonary US for Extubation Success Prediction Thoracic ultrasound - Airway Extubation | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 82 | 2016-05-01 | 2018-12-14 | |
| The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery Dexmedetomidine, Normal saline 0.9% - Airway Extubation | Not applicable | Completed | Severance Hospital | 100 | 2012-02-01 | 2012-08-09 |
Critical Illness (1) · Delirium (1) · Hypersensitivity (1) · Pneumonia, Bacterial (1) · Postoperative Complications (1) · Respiratory Aspiration (1)
Pathological Conditions, Signs and Symptoms (3) · Pathologic Processes (2) · Respiratory Tract Diseases (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Confusion (1) · Disease Attributes (1) · Immune System Diseases (1) · Infections (1) · Lung Diseases (1) · Mental Disorders (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurocognitive Disorders (1) · Neurologic Manifestations (1)
Positive-Pressure Respiration (2) · Airway Extubation (1) · Clinical Protocols (1) · Dexmedetomidine (1) · Isoflurane (1) · Noninvasive Ventilation (1) · Operating Rooms (1) · Propofol (1) · Saline Solution (1)
Hospital do Coracao (2) · Ottawa Hospital Research Institute (2) · Affiliated Hospital of Jiangnan University (1) · Centre Hospitalier Universitaire de Besancon (1) · Centro Hospitalar Unimed de Joinville (1) · Hamad Medical Corporation (1) · Hospital Italiano de Buenos Aires (1) · Hospital Nacional Profesor Alejandro Posadas (1) · Hospital Universitario Doctor Peset (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Peking University First Hospital (1) · Regional Hospital West Jutland (1) · Seoul National University Hospital (1) · Severance Hospital (1)
Argentina (2) · Canada (2) · China (2) · France (2) · South Korea (2) · Spain (2) · Brazil (1) · Mexico (1) · Qatar (1) · United States (1)
Andrew JE Seely, MD, PhD, FRCSC (1) · Dong-Xin Wang, MD, PhD (1) · Jonathan Paillot, MD (1) · Jun Liu, Master (1) · Karen Burns, MD PhD FRCSC (1) · Ladislao P Diaz-Ballve, Lic. (1) · Maria S Venuti, Dr (1) · Paulina E Ezcurra, Lic (1) · Saeyeon Kim, M.D., Ph.D. (1) · Sandro Rizoli (1) · Timothy D Girard, MD, MSCI (1)
PMID 12472328, PMID 14595568, PMID 17470624, PMID 17962636, PMID 18511703, PMID 24108501, PMID 24456585, PMID 24713049, PMID 33730778, PMID 33760875, PMID 35169170, PMID 36526646, PMID 36693401, PMID 36706686, PMID 37572236, PMID 37712728, PMID 37745230, PMID 39444331, PMID 39768558, PMID 40107679, PMID 41130691, PMID 7924494, PMID 9927366
U01HL159882 (1)