30 completed, 4 terminated, 1 active not recruiting, 1 recruiting. 20 Not applicable, 11 Phase 2, 3 Phase 3, 2 Phase 1, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Short Sleep Study Short Sleepers | Recruiting | Danisco | 34 | 2025-10-23 | 2026-08-07 | |
| Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota Increase sleep by 90 minutes, Decrease sleep by 90 minutes - Sleep | Not applicable | Active not recruiting | Danisco | 174 | 2025-09-17 | 2026-10-15 |
| Isolation and Characterization of Multiple Microbial Species From Diverse Healthy Adults Non-interventional - Human Microbiome | Completed | Danisco | 52 | 2021-11-17 | 2023-09-07 | |
| Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation Active product, Control product - Functional Constipation | Not applicable | Completed | Danisco | 224 | 2020-09-16 | 2022-02-23 |
| A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress Probiotic, Placebo - Stress, Psychological, Healthy | Phase 2 | Completed | Danisco | 190 | 2019-09-02 | 2020-03-25 |
| Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Lactose Solution Probiotic, Lactase, Placebo - Lactose Intolerance | Not applicable | Completed | Danisco | 34 | 2018-11-05 | 2019-08-13 |
| Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Fat-free Milk Probiotic, Lactrase, Placebo - Gastrointestinal Symptoms, Breath Test | Not applicable | Completed | Danisco | 34 | 2018-09-11 | 2019-03-05 |
| PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?" Metronidazole, Control: no treatment - Bacterial Vaginosis | Not applicable | Completed | Danisco | 60 | 2017-09-04 | 2017-12-13 |
| Impact of Probiotic Use on Immune Cell Function in Children Probiotic - Respiratory Tract Infections | Not applicable | Completed | University of Wisconsin, Madison | 23 | 2017-05-15 | 2019-12-24 |
| Next Generation Probiotics (NGPs) for Metabolic Health observational - Microbial Colonization | Completed | Danisco | 100 | 2016-04-08 | 2020-01-27 | |
| Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose - Healthy Volunteers | Not applicable | Completed | Danisco | 13 | 2015-09-01 | 2016-07-27 |
| Vetal Laban Intervention Trial Assessing Bowel Symptoms Vetal Laban active, Placebo - Irritable Bowel Syndrome | Phase 4 | Terminated | Danisco | 62 | 2014-03-01 | 2015-12-22 |
| The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass Bifidobacterium animalis ssp. lactis 420, Polydextrose, Placebo - Obesity, Hyperglycemia | Phase 2 | Completed | Danisco | 225 | 2013-11-01 | 2016-02-02 |
| Effect of Probiotic Formula on Reducing the Risk for Antibiotic-associated Diarrhoea Probiotic, Placebo - Antibiotic-associated Diarrhoea | Phase 2 / Phase 3 | Terminated | Danisco | 258 | 2012-12-01 | 2016-01-22 |
| Effect of Probiotic Supplement in Alleviating Functional Gastrointestinal Symptoms Probiotic (Active high), Probiotic (Active low), Placebo - Irritable Bowel Syndrome | Phase 2 | Completed | Danisco | 391 | 2012-10-01 | 2016-01-26 |
| Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function Epicatechin, Microcrystalline cellulose - Borderline Hypertension | Phase 2 | Completed | Danisco | 57 | 2012-08-01 | 2014-04-08 |
| Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment Probiotic, Placebo - Antibiotic Therapy | Phase 2 | Completed | Danisco | 80 | 2012-03-01 | 2012-08-17 |
| Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time Polydextrose, low dose, Polydextrose, medium dose, Polydextrose, high dose - Functional Constipation | Not applicable | Terminated | Danisco | 59 | 2012-03-01 | 2016-01-22 |
| Vitamin K2 Intervention in Patients With Vitamin K Antagonists Vitamin K2 - Thrombosis | Phase 2 | Completed | Danisco | 50 | 2012-02-01 | 2014-04-08 |
| Effect of Probiotic Supplement on Bowel Function Probiotic supplement - Irritable Bowel Syndrome | Phase 2 | Terminated | Danisco | 149 | 2011-06-01 | 2015-08-13 |
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Obesity (4) · Constipation (3) · Diarrhea (3) · Insulin Resistance (3) · Irritable Bowel Syndrome (3) · Metabolic Syndrome (2) · Pain (2) · Abdominal Pain (1) · Bacterial Infections (1) · Cardiovascular Diseases (1) · Communicable Diseases (1) · Dysentery (1) · Endotoxemia (1) · Escherichia coli Infections (1) · Gastroenteritis (1)
Probiotics (10) · Lacteol (5) · microcrystalline cellulose (3) · polydextrose (3) · Arabinose (2) · Catechin (2) · Prebiotics (2) · Synbiotics (2) · 20-aldehyde leukotriene B4 (1) · Adiposity (1) · Control Groups (1) · Glucose (1) · Lactase (1) · Metronidazole (1) · Pentoses (1)
Finland (7) · United Kingdom (6) · United States (6) · Denmark (4) · France (4) · Canada (1) · China (1) · Germany (1) · Ireland (1) · Italy (1) · Netherlands (1) · Saudi Arabia (1)
Anna Lyra, PhD (3) · Arthur Ouwehand, PhD (3) · Sampo Lahtinen, PhD (3) · Anneli Tarpila, PhD (2) · Arthur C Ouwehand, PhD (2) · Kirsti Tiihonen, PhD (2) · Lea Veijola, MD (2) · Yehuda Ringel, MD (2) · Abdullah Aljahdali, MD (1) · Abed Allehibi, Dr (1) · Aila Rissanen, MD (1) · Anna H Lyra, PhD (1) · Anne Lithonius (1) · Arne Astrup, MD DMSC (1) · Arne Astrup, Proffessor (1)
PMID 36149331, PMID 18400707, PMID 18996857, PMID 19651563, PMID 21436726, PMID 21677059, PMID 22373658, PMID 22695039, PMID 23462537, PMID 23510724, PMID 23930950, PMID 24853043, PMID 27810310, PMID 28276900, PMID 28985039, PMID 29078780, PMID 30525950, PMID 32283645, PMID 37662485, PMID 40320938