69 completed, 27 unknown, 8 recruiting, 4 active not recruiting. 98 Not applicable, 7 Phase 2, 4 Early Phase 1, 4 Phase 1, 4 Phase 3.
Follow Prebiotics: new trials by email Literature Review of Prebiotics trials Research Report on Prebiotics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Synbiotic Supplementation on Gastrointestinal Symptoms, Appetite, and Nutritional Recovery in Patients After Autologous Bone Marrow Transplant Tri-component Synbiotic Supplement - Hematologic Neoplasms, Gastrointestinal Symptoms | Not applicable | Not yet recruiting | Alexandria University | 40 | 2026-10-01 | 2026-10-01 |
| Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health Prebiotic, Placebo - Mixed Fiber Supplementation for Healthy Adults | Not applicable | Recruiting | Brown University | 100 | 2026-08-01 | 2026-08-26 |
| Effects of Inulin on Cardiometabolic Risk Factors in Individuals Using Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA ) Medications for Weight Loss inulin (prebiotics), Placebo Comparator: maltodextrin - Obesity & Overweight | Not applicable | Not yet recruiting | Huazhong University of Science and Technology | 600 | 2026-06-01 | 2026-06-03 |
| Impact of Supplementation With Synbiotics and Prebiotics on Cognitive Decline Associated With Neoadjuvant Chemotherapy in First-line Patients With Breast Cancer Synbiotics Blend, Synbiotics + Vitamin D, Prebiotic - Chemobrain, Breast Cancer | Not applicable | Enrolling by invitation | Instituto Jalisciense de Cancerologia | 80 | 2026-02-27 | 2026-03-12 |
| The Effect of Probiotic and Prebiotic Supplementation on Gastrointestinal Health in Individuals With Chronic Spinal Cord Injury Probiotic, Prebiotic - Spinal Cord Injury | Not applicable | Recruiting | Swiss Paraplegic Research, Nottwil | 50 | 2025-08-11 | 2025-10-03 |
| Effect of Inulin Supplementation on Glycaemic Control and Immunological Parameters in Type 1 Diabetes (2024) Inulin (prebiotic, fermentable fiber), Placebo - Type 1 Diabetes Mellitus | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 76 | 2025-05-09 | 2025-07-03 |
| Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women Prebiotic, probiotic, postbiotic combination, Placebo - Gastrointestinal Disease Symptoms | Not applicable | Completed | Colorado State University | 103 | 2025-05-01 | 2026-09-10 |
| Investigation of the Mechanisms of the Gut-brain Axis in Binge Eating and Obesity. Psychobiotic treatment, Placebo treatment - Binge Eating Disorder, Obesity | Phase 1 | Not yet recruiting | Universidade do Porto | 104 | 2025-04-01 | 2025-03-28 |
| Prebiotic Effects on Anxiety, Cortisol, and Emotional Processing in Mild-to-Moderately Stressed Adults Prebiotic (Bimuno®), Placebo - Mild-to-Moderate Stress | Not applicable | Active not recruiting | University of Reading | 55 | 2025-03-31 | 2026-01-08 |
| Effects of Vitamin D and Prebiotic Supplementation on Glucose Control During Pregnancy Vitamin D3, Prebiotics, Prebiotics placebo - Glucose Intolerance During Pregnancy | Not applicable | Recruiting | Huazhong University of Science and Technology | 500 | 2025-02-24 | 2025-09-16 |
| PROMOTE: The Effect of a Six Week Prebiotic Supplementation on Wellbeing of Young Adults. Prebiotic, Maltodextrin (Corn) - Wellbeing, Healthy | Not applicable | Withdrawn | University of Southampton | 2025-01-06 | 2026-05-13 | |
| Probiotic and Prebiotic Use in Early Postoperative Period of Sleeve Gastrectomy Probiotic and Prebiotic - Sleeve Gastrectomy, Gastrointestinal Symptoms | Not applicable | Completed | Ayten Altunsaray | 60 | 2024-12-24 | 2026-10-15 |
| Effect of a Low-calorie Diet With a Prebiotic Supplement on Health of Overweight-obese Subjects. Prebiotic + hypocaloric diet, Placebo + hypocaloric diet - Polyphenols, Obesity | Not applicable | Completed | Clinica Universidad de Navarra, Universidad de Navarra | 156 | 2024-12-13 | 2025-05-30 |
| To Study the Effect of SC-FOS Prebiotics in Women With Polycystic Ovary Syndrome Short Chain Fructooligosaccharides, Placebo Group - Polycystic Ovary Syndrome | Not applicable | Unknown | Universidad Autonoma de Chihuahua | 40 | 2024-12-02 | 2024-02-05 |
| To Study the Effect of Short-chain Fructooligosaccharides in Women With Irritable Bowel Syndrome Short Chain Fructooligosaccharides, Corn Starch - Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome | Not applicable | Unknown | Universidad Autonoma de Chihuahua | 40 | 2024-12-02 | 2024-02-05 |
| Investigating the Bactericidal Effect of Probiotics on Chromogenic Bacteria in Children An In Vivo and In Vitro Study Probiotic with Prebiotic - Black Stains | Phase 4 | Completed | Ain Shams University | 9 | 2024-11-05 | 2025-04-16 |
| A Study to Evaluate the Effects of a Prebiotic and Probiotic Supplement to Provide Relief From Symptoms Associated With Bacterial Vaginosis and Yeast Infections. Prebiotic + Probiotic Supplement, Active Placebo Supplement, Excipient Placebo Supplement - Bacterial Vaginosis, Yeast Infection | Not applicable | Completed | Happy V | 120 | 2024-10-04 | 2026-08-13 |
| A Comprehensive Analysis of the Comparative Efficacy of Multimodal Diarrhea Therapies in the Paediatric Population Prebiotic, Duration, Smecta - To Assess the Mean Time of Resolution of Diarrhea | Early Phase 1 | Unknown | Combined Military Hospital Multan | 100 | 2024-09-15 | 2024-09-19 |
| Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome Fish oil, Probiotics, Prebiotics - Perinatal Depression, PerinatalAnxiety | Phase 2 / Phase 3 | Recruiting | The Canadian College of Naturopathic Medicine | 100 | 2024-08-15 | 2024-08-27 |
| Impact of Prebiotics in Ulcerative Colitis Prebiotic - Crohn Disease, Ulcerative Colitis | Not applicable | Recruiting | University of California, Los Angeles | 70 | 2024-07-09 | 2026-02-27 |
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Obesity (7) · Constipation (6) · Diabetes Mellitus, Type 1 (4) · Schizophrenia (4) · Colitis, Ulcerative (3) · Inflammation (3) · Irritable Bowel Syndrome (3) · Stress, Psychological (3) · Anemia, Iron-Deficiency (2) · Anxiety Disorders (2) · Cognitive Dysfunction (2) · Crohn Disease (2) · Dermatitis, Atopic (2) · Diarrhea (2) · Dysbiosis (2)
University of Reading (7) · Hospital Universitari Vall d'Hebron Research Institute (3) · Huazhong University of Science and Technology (3) · University of Calgary (3) · Beneo-Institute (2) · Danone Nutricia (2) · Mead Johnson Nutrition (2) · Société des Produits Nestlé (SPN) (2) · Sprim Advanced Life Sciences (2) · Swiss Federal Institute of Technology (2) · Universidad Autonoma de Chihuahua (2) · Universidade Federal de Santa Catarina (2) · University of Oxford (2) · AB Biotics, SA (1) · AC Camargo Cancer Center (1)
United States (22) · United Kingdom (18) · Spain (11) · Canada (8) · China (8) · Netherlands (7) · Brazil (6) · Belgium (3) · France (3) · Germany (3) · Italy (3) · Mexico (3) · Turkey (Türkiye) (3) · Bulgaria (2) · Egypt (2)
An Pan, PHD (2) · Gang Liu, PHD (2) · Alp Sener, MD (1) · An Pan (1) · Ana Lorente (1) · Ariana Salavert, PhD (1) · Aybegum Kalyoncu Aycenk, Assistant Professor (1) · Belinda Lennox, MD (1) · Blagovesta Yaneva, PhD (1) · Carol Huang, MD, PhD (1) · Carol L Berseth, M.D. (1) · Carol Lynn Berseth, MD (1)
PMID 37870148, PMID 39470206, PMID 11297958, PMID 12612204, PMID 12788576, PMID 15541456, PMID 15711820, PMID 16197582, PMID 17060763, PMID 18025796, PMID 19017418, PMID 19524376, PMID 20128938, PMID 20844065, PMID 20948557, PMID 20970896, PMID 21593355, PMID 21626296, PMID 21945174, PMID 21979491, PMID 22228076, PMID 22453296, PMID 22836031, PMID 23238584, PMID 23578724, PMID 23915796, PMID 24131826, PMID 24643131, PMID 25909598, PMID 26151493, PMID 26571488, PMID 26985232, PMID 27048903, PMID 27057326, PMID 27456494, PMID 27478897, PMID 27543643, PMID 28215759, PMID 28223062, PMID 29270002, PMID 29381586, PMID 29662493, PMID 30514364, PMID 30515164, PMID 30586752, PMID 30876680, PMID 31004135, PMID 31005913, PMID 31188437, PMID 32320024
R01ES030940 (1), R61AT009990 (1)