14 completed, 2 active not recruiting, 2 recruiting, 1 terminated. 19 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 14, Active not recruiting 2, Recruiting 2, Terminated 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Weight Gain: new trials by email Literature Review of Weight Gain trials Research Report on Weight Gain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| No Guts No Glory Probiotics Probiotic Formula, Placebo - Patients Using Olanzapine, Quetiapine, Risperidone or Clozapine | Phase 2 / Phase 3 | Recruiting | University Medical Center Groningen | 112 | 2026-06-01 | 2026-05-26 |
| Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) Dapagliflozin 10mg Tab, Pitavastatin 4 Mg Oral Tablet, Rosuvastatin and Ezetimibe - HIV Infections, Weight Gain | Phase 3 | Active not recruiting | Kirby Institute | 300 | 2024-12-16 | 2026-07-22 |
| A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2) Tirzepatide, Placebo - Obesity, Weight Gain | Phase 3 | Recruiting | Eli Lilly and Company | 300 | 2024-06-03 | 2026-09-24 |
| Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity Empagliflozin 10 MG, MetFORMIN 500 Mg Oral Tablet - Polycystic Ovary Syndrome, Weight Gain | Phase 2 / Phase 3 | Completed | SINA Health Education and Welfare Trust | 70 | 2023-12-15 | 2025-05-14 |
| A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy Delstrigo, KOCITAF - HIV-1-infection | Phase 3 | Active not recruiting | Professor Francois Venter | 600 | 2023-11-08 | 2025-04-02 |
| Laser Acupuncture for Postpartum Weight Retention laser acupuncture, sham laser acupuncture - Postpartum Weight Retention | Phase 3 | Completed | Chang Gung Memorial Hospital | 66 | 2014-01-01 | 2017-01-16 |
| Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - Phoenix Enhanced standard care, Intensive lifestyle intervention - Obesity, Diet Therapy | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 123 | 2013-03-28 | 2026-10-08 |
| Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects Depot medroxyprogesterone acetate (DMPA) - Weight Gain, Disorder of Bone Density and Structure, Unspecified | Phase 3 | Completed | Nationwide Children's Hospital | 34 | 2011-09-01 | 2018-04-23 |
| eMOMS of Rochester electronic intervention during pregnancy and postpartum, electronic intervention during pregnancy, Control - Gestational Weight Gain, Postpartum Weight Retention | Phase 3 | Completed | University of Rochester | 1641 | 2011-05-01 | 2015-12-02 |
| Multi-vitamins, HAART and HIV/AIDS in Uganda Multivitamin supplements B,C and E - HIV/AIDS | Phase 3 | Completed | Harvard School of Public Health (HSPH) | 400 | 2010-04-01 | 2014-05-22 |
| Cannabinoid Receptor (CB1) Agonist Treatment in Severe Chronic Anorexia Nervosa dronabinol, placebo - Anorexia Nervosa | Phase 3 | Completed | Odense University Hospital | 24 | 2008-10-01 | 2013-05-10 |
| A Study of Zonisamide to Prevent Olanzapine-Associated Weight Gain zonisamide, olanzapine, Zonisamide - Weight Gain | Phase 3 | Completed | Lindner Center of HOPE | 42 | 2008-01-01 | 2012-04-13 |
| Efficacy and Safety of Treatment With Balaglitazone in Type 2 Diabetes Patients on Stable Insulin Therapy Balaglitazone - Diabetes Mellitus, Type 2 | Phase 3 | Completed | Rheoscience A/S | 409 | 2007-07-01 | 2010-07-23 |
| Promoting Healthy Weight Gain During Pregnancy Lifestyle - Weight Gain | Phase 3 | Completed | The Miriam Hospital | 401 | 2007-03-01 | 2013-05-01 |
| Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids Olanzapine, Omega 3, Vitamin E+C - Schizophrenia | Phase 3 | Terminated | Augusta University | 20 | 2005-10-01 | 2012-10-24 |
| LANN-study: Lantus, Amaryl, Novorapid, Novomix Study Novomix 30, Novorapid and Amaryl, Lantus - Diabetes Mellitus Type II | Phase 3 | Completed | Rijnstate Hospital | 150 | 2005-05-01 | 2011-08-09 |
| Prevention of Weight Gain in Adult Patients With Type 2 Diabetes Treated With Pioglitazone Lifestyle modification - Type 2 Diabetes, Obesity | Phase 3 | Completed | Northwestern University | 39 | 2003-09-01 | 2008-08-19 |
| Preterm Infants' Weight Gain Following Massage Therapy massage, Sham massage - Premature Birth | Phase 3 | Completed | University of Miami | 139 | 2003-04-01 | 2014-04-10 |
| Supplemental Calcium in Overweight People Calcium supplement, Placebo - Obesity | Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 540 | 2002-02-06 | 2019-11-22 |
Obesity (5) · Diabetes Mellitus, Type 2 (4) · Gestational Weight Gain (2) · Psychotic Disorders (2) · Schizophrenia (2) · Acquired Immunodeficiency Syndrome (1) · Anorexia Nervosa (1) · Behavior (1) · Bipolar Disorder (1) · Body Weight (1) · Bronchiolitis Obliterans Syndrome (1) · Diabetes Mellitus (1) · Edema (1) · HIV Infections (1)
Body Weight Changes (19) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (19) · Body Weight (18) · Nutritional and Metabolic Diseases (8) · Endocrine System Diseases (5) · Glucose Metabolism Disorders (5) · Metabolic Diseases (5) · Nutrition Disorders (5) · Overnutrition (5) · Overweight (5) · Urogenital Diseases (5) · Genital Diseases (4) · Mental Disorders (4) · Diabetes Mellitus (3)
Olanzapine (2) · Tablets (2) · Control Groups (1) · Docosahexaenoic Acids (1) · Dronabinol (1) · Ezetimibe (1) · Insulin Aspart (1) · Insulin Glargine (1) · Low-Level Light Therapy (1) · Massage (1) · Metformin (1) · Postpartum Period (1) · Pregnancy (1) · Rosuvastatin Calcium (1) · Sugars (1)
Augusta University (1) · Chang Gung Memorial Hospital (1) · Eli Lilly and Company (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Harvard School of Public Health (HSPH) (1) · Kirby Institute (1) · Lindner Center of HOPE (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Nationwide Children's Hospital (1) · Northwestern University (1) · Odense University Hospital (1) · Professor Francois Venter (1) · Rheoscience A/S (1) · Rijnstate Hospital (1) · SINA Health Education and Welfare Trust (1)
United States (9) · Argentina (2) · Australia (2) · Denmark (2) · Netherlands (2) · South Africa (2) · Taiwan (2) · Uganda (2) · Canada (1) · France (1) · Germany (1) · India (1) · Israel (1) · Malaysia (1) · Mexico (1)
Andrea Bonny, MD (1) · Andries Alin, physician (1) · Bente J Riis, MD (1) · Christine M Olson, PhD (1) · David Guwatudde, MPH, PhD (1) · Gail Matthews, MD (1) · Hans de Boer, MD, PhD (1) · Hina Sharif, PharmD,MSPH (1) · Iris E.C. Sommer, Prof. Dr. (1) · Isabel D Fernandez, MD, MPH, PhD (1) · Jack A Yanovski, M.D. (1) · Mary A Hoskin, R.D. (1) · Peter Buckley, M.D. (1)
PMID 18714203, PMID 19528561, PMID 20821818, PMID 21310836, PMID 21328517, PMID 22367654, PMID 23151221, PMID 24284438, PMID 25143156, PMID 25957183, PMID 26285704, PMID 26708836, PMID 28069560, PMID 28525293, PMID 28573669, PMID 29718281, PMID 29743026, PMID 30230252, PMID 30937899, PMID 33238176, PMID 34088249, PMID 38271099, PMID 40839263, PMID 41029405, PMID 41257673, PMID 42050587, PMID 42536019
R01AT000370 (1)