271 completed, 55 unknown, 44 recruiting, 21 terminated. 278 Not applicable, 29 Phase 4, 24 Phase 2, 19 Phase 3, 7 Phase 1.
Follow Weight Gain: new trials by email Literature Review of Weight Gain trials Research Report on Weight Gain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Weight Changes After Incretin-mimetics discontinuation of weight loss medication - Obesity and Obesity-related Medical Conditions | Not applicable | Not yet recruiting | Medical College of Wisconsin | 52 | 2026-12-01 | 2026-02-24 |
| An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being Intuitive Eating Intervention - Excessive Gestational Weight Gain, Pregnancy | Not applicable | Recruiting | San Diego State University | 80 | 2026-11-01 | 2026-11-06 |
| Tapered Versus Abrupt Discontinuation of Semaglutide After Treatment of Recurrent Weight Gain or Suboptimal Response Following Metabolic and Bariatric Surgery Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight Gain Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Semaglutide 2.4 mg Once Weekly for Recurrent Weight Gain After Metabolic and Bariatric Surgery (RESURGE) Semaglutide weekly injection, Placabo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 104 | 2026-10-01 | 2026-10-05 |
| Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study Dolutegravir (DTG) AND Tenofovir alafenamide (TAF), Tenofovir Disoproxil Fumarate, Dolutegravir - Healthy Volunteer, Weight Gain | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 120 | 2026-09-24 | 2026-09-29 |
| Nutritional Responses to Acute Exercise Performed on the LipoxMax in Obese Adolescents The participants in this study are adolescents with obesity (with a Body Mass Index above the 95th percentile on international growth charts) - Weight Gain, Weight Loss | Not applicable | Not yet recruiting | Centre Hospitalier Emile Roux | 18 | 2026-09-01 | 2026-09-28 |
| Healthy Adaptation to Pregnancy, Postpartum and Parenthood HAP3 Family App - Perinatal Mental Health, Gestational Weight Gain | Not applicable | Not yet recruiting | KU Leuven | 572 | 2026-09-01 | 2026-09-23 |
| Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies Food Kit - Pregnant Women With Singleton Pregnancies | Not applicable | Recruiting | Texas A&M University | 800 | 2026-06-22 | 2026-06-30 |
| No Guts No Glory Probiotics Probiotic Formula, Placebo - Patients Using Olanzapine, Quetiapine, Risperidone or Clozapine | Phase 2 / Phase 3 | Recruiting | University Medical Center Groningen | 112 | 2026-06-01 | 2026-05-26 |
| Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL) Exercises - Leukemia, Acute Leukemia | Not applicable | Recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-05-01 | 2026-08-03 |
| "Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease " High-Calorie Specialized Nutritional Formula, education program, High-Calorie Diet - Weight Gain, Body Mass Index | Not applicable | Not yet recruiting | Aryan Najmadin Nasradin | 75 | 2026-04-17 | 2026-04-29 |
| Gestational Response, Outcomes, and Weight After GLP-1 Use Pregnant Individuals, Obesity & Overweight | Recruiting | University of Kansas Medical Center | 400 | 2026-04-13 | 2026-08-04 | |
| Premature Infant Oral Motor Intervention vs. Pacifier for Oral Feeding Transition in Preterm Infants Premature Infant Oral Motor Intervention (PIOMI), Pacifier Use (Non-Nutritive Sucking) - Feeding Difficulties, Sucking Behavior | Not applicable | Not yet recruiting | University of Baghdad | 150 | 2026-03-10 | 2026-03-10 |
| Focused Echocardiography for Primary Care Physicians point of care ultrasound - Age 65 and Older, Cardiac Risk Factors | Not applicable | Not yet recruiting | University Hospital, Caen | 300 | 2026-03-01 | 2026-02-23 |
| Incretin Microdosing for Cardiometabolic Health in People With HIV Dose escalation to 2 mg semaglutide weekly then semaglutide microdosing at 0.5 mg weekly, Dose escalation to 2 mg semaglutide weekly then no semaglutide - Weight Gain | Phase 2 | Recruiting | The University of Texas Health Science Center, Houston | 30 | 2026-02-12 | 2026-02-18 |
| Metabolic Changes Associated With Weight Gain After Treatment of Achalasia Achalasia, Esophageal | Not yet recruiting | Assaf-Harofeh Medical Center | 30 | 2026-01-15 | 2026-01-13 | |
| Gestational Weight Loss and Restrictive Weight Gain in Maternal Obesity: A Target Trial Emulation Gestational Weight Gain (GWG) Strategy - Pregnancy, Obesity | Completed | Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School | 205636 | 2026-01-01 | 2026-11-06 | |
| Mother and Offspring's Nutritional Status -Pregnancy After Maternal Bariatric Surgery Post-Bariatric Maternal and Infant Health Study, Observation arm - Bariatric Surgery, Pregnency | Recruiting | Helse Nord-Trøndelag HF | 210 | 2025-12-25 | 2026-10-20 | |
| Effect of Gestational Weight Gain on Spinal Anesthesia in Elective Cesarean Delivery Gestational Weight Gain - Gestational Weight Gain, Regional Anesthesia | Completed | Elazıg Fethi Sekin Sehir Hastanesi | 120 | 2025-12-05 | 2026-09-10 |
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Obesity (163) · Gestational Weight Gain (134) · Overweight (47) · Motor Activity (40) · Weight Loss (37) · Diabetes, Gestational (28) · Schizophrenia (26) · Psychotic Disorders (17) · Diabetes Mellitus (16) · Feeding Behavior (16) · Insulin Resistance (16) · Metabolic Syndrome (15) · Body Weight (14) · Premature Birth (14)
Pathological Conditions, Signs and Symptoms (430) · Signs and Symptoms (428) · Body Weight Changes (419) · Body Weight (416) · Nutritional and Metabolic Diseases (235) · Nutrition Disorders (190) · Overnutrition (182) · Overweight (137) · Behavior (88) · Metabolic Diseases (83) · Glucose Metabolism Disorders (79) · Urogenital Diseases (73) · Female Urogenital Diseases and Pregnancy Complications (66) · Endocrine System Diseases (60)
Exercise (13) · Control Groups (11) · Metformin (11) · Olanzapine (8) · Nutrition Assessment (6) · Pregnancy (6) · Diet (5) · Diet Therapy (5) · Nutritional Status (5) · Aripiprazole (4) · Counseling (4) · Resistance Training (4) · Standard of Care (4) · Behavior Therapy (3) · Massage (3)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (8) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (7) · Wake Forest University Health Sciences (7) · Stanford University (6) · University of Kansas Medical Center (6) · University of Michigan (6) · University of Pennsylvania (6) · Johns Hopkins University (5) · Peking Union Medical College Hospital (5) · Pennington Biomedical Research Center (5) · University of Alabama at Birmingham (5) · University of North Carolina, Chapel Hill (5) · Washington University School of Medicine (5) · International Centre for Diarrhoeal Disease Research, Bangladesh (4) · Universiti Putra Malaysia (4)
United States (195) · Canada (22) · China (13) · Denmark (12) · Turkey (Türkiye) (11) · France (10) · United Kingdom (10) · Brazil (9) · Germany (8) · Bangladesh (7) · Israel (7) · Spain (7) · Sweden (7) · Indonesia (5) · Italy (5)
Jack A Yanovski, M.D. (4) · Christina A Roberto, PhD (3) · Holly Hull, PhD (3) · Linmarie Sikich, MD (3) · Suzanne Phelan, PhD (3) · Alexander Stehle Young, MD MSHS (2) · Camille S Worthington, PhD (2) · Camille Worthington, PhD (2) · Ching Fang Lee, PhD (2) · Donna Ames, MD (2) · Eric Stice, PhD (2) · Kavita Juneja, MD (2) · Knut Mai, Prof (2) · Kyle Burger, PhD (2) · Leanne M Redman, Ph.D. (2)
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P50MD017338 (3), R01DK113307 (2), 2016 (1), 2018 (1), D43TW009135 (1), K23HD108345 (1), K23HL153667 (1), KL2TR002539 (1), P20GM109096 (1), P20GM144269 (1), P30DK089503 (1), P30DK092950 (1), P30MH082760 (1), P50MD017348 (1), R00HL163474 (1)