Urogenital Abnormalities: Clinical Trials

292 completed, 106 unknown, 96 recruiting, 36 terminated. 167 Not applicable, 90 Phase 2, 49 Phase 3, 46 Phase 4, 35 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	167	Completed 76, Unknown 37, Recruiting 23, Not yet recruiting 11, Active not recruiting 8, Terminated 4, Withdrawn 4, Enrolling by invitation 3, Suspended 1
Phase 2	90	Completed 44, Recruiting 11, Terminated 10, Active not recruiting 8, Unknown 8, Not yet recruiting 6, Withdrawn 2, Enrolling by invitation 1
Phase 3	49	Completed 28, Recruiting 7, Active not recruiting 5, Not yet recruiting 3, Unknown 3, Terminated 2, Withdrawn 1
Phase 4	46	Completed 26, Unknown 10, Recruiting 7, Enrolling by invitation 1, Not yet recruiting 1, Withdrawn 1
Phase 1	35	Completed 16, Terminated 7, Recruiting 3, Unknown 3, Active not recruiting 2, Not yet recruiting 2, Withdrawn 2
Early Phase 1	9	Recruiting 4, Unknown 3, Terminated 1, Withdrawn 1

Follow Urogenital Abnormalities: new trials by email Literature Review of Urogenital Abnormalities trials Research Report on Urogenital Abnormalities

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Development of Healthcare Transition for Patients With Congenital Adrenal Hyperplasia exposure to healthcare transition protocol - Congenital Adrenal Hyperplasia		Not yet recruiting	University of Alabama at Birmingham	40	2027-01-01	2026-10-14
Efficacy, Safety, Tolerability, and Pharmacokinetics of NBIP-01435 in Adult Participants With Classic Congenital Adrenal Hyperplasia (CAH) NBIP-01435 - Congenital Adrenal Hyperplasia	Phase 2	Not yet recruiting	Neurocrine Biosciences	36	2026-12-01	2026-09-30
SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years Semaglutide (Wegovy) weekly injection, Placebo weekly Injection - Craniopharyngioma, Child	Phase 3	Not yet recruiting	University Hospital, Angers	50	2026-11-01	2026-09-29
A Pilot Study Comparison of Programmed Intermittent Bolus Versus Continuous Infusion Ropivacaine (Epidural analgesia) intermittent bolus, Ropivacaine (Epidural analgesia) continuous infusion, Chloroprocaine intermittent bolus - Bladder Extrophy, Surgery in Children	Not applicable	Not yet recruiting	Giorgio Veneziano	10	2026-11-01	2026-09-28
Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis	Phase 4	Not yet recruiting	Jay C. Buckey Jr.	100	2026-11-01	2026-09-09
MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT) Antiphospholipid (aPL)-Positive, Rheumatic Arthritis		Not yet recruiting	Axiom Bioregistry	5000	2026-10-18	2026-10-23
An Extension Trial of Asedebart in Participants With Congenital Adrenal Hyperplasia Asedebart - Adrenal Hyperplasia, Congenital	Phase 2	Not yet recruiting	H. Lundbeck A/S	45	2026-10-01	2026-10-05
Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS Metyrapone 250 mg Oral Tablets, Placebo - Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS)	Phase 2	Recruiting	Mayo Clinic	90	2026-10-01	2026-09-25
Sexual Quality of Life in Female Patients With Lipodystrophy Syndromes or Turner's Syndrome: a Case-control Study Lipodystrophy Congenital Generalized, Lipodystrophy, Familial Partial		Not yet recruiting	Assistance Publique - Hôpitaux de Paris	1416	2026-10-01	2026-09-02
Hematological Profile in Children With Numerical Chromosomal Disorders Down Syndrome, Turner Syndrome		Not yet recruiting	Assiut University	158	2026-09-02	2026-09-10
Pre-pubertal Low Dose Transdermal Estradiol in Turner Syndrome Estradiol transdermal patch 0.025mg/24 hours- 1/8th fractionated patch - Turner Syndrome, Primary Ovarian Insufficiency	Phase 2	Not yet recruiting	Children's National Research Institute	15	2026-09-01	2026-08-25
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS) Extended Serum Biomarker and Hormonal Panel, Liver Elastography with Controlled Attenuation Parameter, Targeted Genotyping of PNPLA3 rs738409 and HSD17B13 rs72613567 - Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease		Not yet recruiting	Kayseri City Hospital	150	2026-09-01	2026-07-30
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) Beef+ - PCOS (Polycystic Ovary Syndrome), Obese Adolescents	Not applicable	Recruiting	Texas A&M University	36	2026-09-01	2026-08-21
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of OMS1620 OMS1620, Placebo - Congenital Adrenal Hyperplasia (CAH)	Phase 1	Not yet recruiting	OMass Therapeutics Australia Proprietary Ltd	84	2026-09-01	2026-09-09
Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia Congenital Adrenal Hyperplasia, Adrenal Insufficiency		Not yet recruiting	Assistance Publique - Hôpitaux de Paris	50	2026-09-01	2026-07-21
Efficacy of PRF in Hypospadias Repair Tubularized Incised Plate urethroplasty with intraoperative placement of autologous PRF onto the urethral plate., standard Tubularized Incised Plate urethroplasty - Hypospadias	Not applicable	Not yet recruiting	Ain Shams University	80	2026-08-01	2026-08-11
Hydrocortisone Modified-release in Adults: Real-world Monitoring of Longitudinal Outcomes in coNgenital Adrenal hYperplasia CAH - Congenital Adrenal Hyperplasia		Not yet recruiting	IRCCS San Raffaele	100	2026-07-31	2026-06-08
Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary Syndrome Polycystic Ovary Syndrome (PCOS), Insulin Resistance		Not yet recruiting	GÜLDEN ANATACA	60	2026-07-30	2026-07-30
Pediatric Congenital Adrenal Hyperplasia Management: Regret and Long-term Outcomes questionnaire - Classic Congenital Adrenal Hyperplasia, 21-Hydroxylase Deficiency		Recruiting	University Hospital, Lille	40	2026-07-08	2026-08-24
The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short Stature Inpegsomatropin-Injection, Givopegsomatropin Solution Injection - Turner Syndrome	Phase 3	Recruiting	Xiamen Amoytop Biotech Co., Ltd.	84	2026-07-05	2026-07-22

Showing 20 of 619. Sign in to see all of them.

Narrower conditions

Turner Syndrome (124)  ·  Hypospadias (108)  ·  Adrenal Hyperplasia, Congenital (99)  ·  Hyperandrogenism (81)  ·  Polycystic Ovary Syndrome (59)  ·  Klinefelter Syndrome (47)  ·  Nephritis, Hereditary (38)  ·  Cryptorchidism (37)  ·  Disorders of Sex Development (32)  ·  Hypogonadism (30)  ·  Kallmann Syndrome (23)  ·  Sexual Infantilism (23)  ·  Insulin Resistance (22)  ·  Bladder Exstrophy (16)  ·  Down Syndrome (16)

Broader conditions

Urogenital Diseases (617)  ·  Male Urogenital Diseases (611)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (606)  ·  Congenital Abnormalities (600)  ·  Female Urogenital Diseases and Pregnancy Complications (590)  ·  Female Urogenital Diseases (589)  ·  Gonadal Disorders (446)  ·  Endocrine System Diseases (443)  ·  Disorders of Sex Development (382)  ·  Genetic Diseases, Inborn (283)  ·  Genital Diseases (230)  ·  Adrenogenital Syndrome (175)  ·  Chromosome Disorders (164)  ·  Nutritional and Metabolic Diseases (162)

Interventions

Human Growth Hormone (24)  ·  Hydrocortisone (13)  ·  Metformin (13)  ·  Estradiol (10)  ·  Growth Hormone (10)  ·  Blood Specimen Collection (9)  ·  Dexamethasone (8)  ·  Gonadotropin-Releasing Hormone (8)  ·  Progesterone (7)  ·  Bupivacaine (6)  ·  Dexmedetomidine (6)  ·  Ropivacaine (6)  ·  crinecerfont (6)  ·  Estrogens (5)  ·  Exenatide (5)

Sponsors

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (18)  ·  University of Aarhus (17)  ·  Assiut University (16)  ·  Assistance Publique - Hôpitaux de Paris (13)  ·  Novo Nordisk A/S (12)  ·  University of Colorado, Denver (11)  ·  University of Virginia (11)  ·  Hospices Civils de Lyon (10)  ·  Massachusetts General Hospital (10)  ·  IRCCS Azienda Ospedaliero-Universitaria di Bologna (8)  ·  Neurocrine UK Limited (8)  ·  Ain Shams University (7)  ·  Rhythm Pharmaceuticals, Inc. (7)  ·  Johns Hopkins University (6)  ·  Natera, Inc. (6)

Countries

United States (236)  ·  France (77)  ·  Italy (40)  ·  United Kingdom (40)  ·  Egypt (36)  ·  Germany (35)  ·  Spain (34)  ·  Denmark (30)  ·  China (28)  ·  Turkey (Türkiye) (25)  ·  Netherlands (23)  ·  Canada (21)  ·  South Korea (20)  ·  Poland (16)  ·  Sweden (15)

Top investigators

David Meeker, MD (6)  ·  Stephanie B Seminara, MD (5)  ·  Veronica Gomez-Lobo, M.D. (4)  ·  Christine Burt Solorzano, MD (3)  ·  Clifford E Kashtan, MD (3)  ·  Deborah P Merke, M.D. (3)  ·  Shanlee M Davis, MD (3)  ·  Shanlee M Davis, MD, PhD (3)  ·  Alessandra Gambineri, MD (2)

Results publications

PMID 40938675, PMID 33159213, PMID 36978128, PMID 32034419, PMID 33527139, PMID 20634140, PMID 21209029, PMID 22568526, PMID 23643382, PMID 24325905, PMID 26091193, PMID 31132118, PMID 32507565, PMID 32542985, PMID 32870266, PMID 34146101, PMID 35031224, PMID 35644790, PMID 38724717, PMID 38828955, PMID 10417280, PMID 10518081, PMID 10599727, PMID 10599729, PMID 10631746, PMID 10634337, PMID 10799234, PMID 10893631, PMID 10971284, PMID 11476780, PMID 11488741, PMID 11531930, PMID 11713004, PMID 11739428, PMID 11788640, PMID 12015520, PMID 12213860, PMID 12466334, PMID 12629094, PMID 12785564, PMID 12788881, PMID 12820840, PMID 12837712, PMID 14573733, PMID 15008773, PMID 15613419, PMID 15784709, PMID 15900109, PMID 16489933, PMID 16516617

NIH funding

2023 (5), P50HD028934 (4), U54HD028138 (4), UL1TR001082 (4), 2009 (3), 2015 (2), 2018 (2), 2019 (2), U54HD028934 (2), 2004 (1), 2008 (1), 2017 (1), 268201000048C-5-0-1 (1), K01MH083045 (1), K12DK100022 (1)