13 completed. 13 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 13 |
| Phase 2 | 4 | Completed 4 |
Follow Tobacco Dependence: new trials by email Literature Review of Tobacco Dependence trials Research Report on Tobacco Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy Nicotine Spray, Placebo - Tobacco Dependence | Phase 3 | Completed | McNeil Consumer Healthcare Division of McNEIL-PPC, Inc. | 1198 | 2015-01-31 | 2019-01-08 |
| Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence Omega 3, Placebo - Tobacco Dependence, Nicotine Dependence | Phase 3 | Completed | Federal University of São Paulo | 58 | 2013-01-01 | 2020-10-14 |
| Tailoring Varenicline to Individual Needs (TVIN Study) Varenicline, Placebo - Tobacco Dependence, Smoking Cessation | Phase 3 | Completed | Queen Mary University of London | 200 | 2011-07-01 | 2013-04-25 |
| Varenicline Treatment for Active Alcoholic Smokers Varenicline, placebo - Smoking, Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 33 | 2011-06-01 | 2018-02-05 |
| Tobacco Intervention in Buprenorphine Treatment Innovative System, Standard Treatment Control (STC) - Tobacco Dependence | Phase 3 | Completed | University of California, San Francisco | 175 | 2011-04-01 | 2018-11-13 |
| Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study) Nicotine Patch, Placebo, Varenicline - Tobacco Dependence, Smoking Cessation | Phase 3 | Completed | Queen Mary University of London | 117 | 2011-04-01 | 2012-10-11 |
| Efficacy and Safety of Varenicline Among HIV-infected Patients Varenicline, Placebo - HIV Infections, Tobacco Dependence | Phase 3 | Completed | ANRS, Emerging Infectious Diseases | 248 | 2009-10-01 | 2014-07-29 |
| Use of Varenicline for 4-weeks Prior to Quitting Varenicline, Placebo - Tobacco Dependence, Smoking Cessation | Phase 3 | Completed | Queen Mary University of London | 101 | 2009-07-01 | 2013-12-12 |
| Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction nicotine lozenges, tobacco-free snuff - Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 81 | 2009-01-01 | 2013-09-13 |
| S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence S-Adenosyl-L-Methionine, placebo - Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 150 | 2008-09-01 | 2011-09-09 |
| Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study Placebo (sugar pill), Topiramate, Nicotine patch - Tobacco Dependence | Phase 3 | Completed | UConn Health | 57 | 2006-04-01 | 2017-08-16 |
| Reducing Ethnic Health Disparities: Motivating HIV+ Latinos to Quit Smoking Standard Care Intervention (SCI), Culturally Tailored Intervention (CTI) - Tobacco Dependence, HIV Infections | Phase 3 | Completed | Butler Hospital | 400 | 2005-10-01 | 2013-05-03 |
| Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence Nicotine Patch, Nicotine Gum - Tobacco Dependence | Phase 2 / Phase 3 | Completed | National Institute on Drug Abuse (NIDA) | 157 | 1999-08-01 | 2017-01-12 |
Tobacco Use Disorder (13) · Smoking Cessation (4) · Smoking (3) · HIV Infections (2) · Tobacco Use (2) · Alcoholism (1) · Behavior, Addictive (1)
Chemically-Induced Disorders (13) · Mental Disorders (13) · Substance-Related Disorders (13) · Behavior (9) · Health Behavior (4) · Blood-Borne Infections (2) · Communicable Diseases (2) · Genital Diseases (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2) · Infections (2) · Lentivirus Infections (2) · RNA Virus Infections (2) · Retroviridae Infections (2) · Sexually Transmitted Diseases (2)
Tobacco Use Cessation Devices (5) · Varenicline (5) · Sugars (3) · Docosahexaenoic Acids (1) · Fatty Acids, Omega-3 (1) · Fish Oils (1) · Mineral Oil (1) · Nicotine (1) · Nicotine Chewing Gum (1) · S-Adenosylmethionine (1) · Topiramate (1)
Mayo Clinic (3) · Queen Mary University of London (3) · ANRS, Emerging Infectious Diseases (1) · Butler Hospital (1) · Federal University of São Paulo (1) · McNeil Consumer Healthcare Division of McNEIL-PPC, Inc. (1) · National Institute on Drug Abuse (NIDA) (1) · UConn Health (1) · University of California, San Francisco (1)
United States (8) · United Kingdom (3) · Brazil (1) · France (1)
Al-Rehan A A Dhanji, MB BS BSc MRCP (1) · Al-Rehan A A Dhanji, MB BS BSc MRCS (1) · Al-Rehan Abdul Aziz Dhanji, MB.BS., BSc.,MRCS. (1) · Amit Sood, M.D. (1) · Andrew Myers, MD (1) · Cassandra Stanton, Ph.D. (1) · Cheryl A Oncken, MD (1) · Eric T. Moolchan, M.D. (1) · Jon O Ebbert, MD (1) · Richard D. Hurt, MD (1) · Sharon Hall, PhD (1)
PMID 37142273, PMID 34611902, PMID 39101506, PMID 21518946, PMID 23454876, PMID 23718718, PMID 24057996, PMID 25545858, PMID 28549161, PMID 29324248, PMID 29329763, PMID 30452732, PMID 37230961, PMID 39868569
2008 (1), K24AA013736 (1), M01RR006192 (1), P50DA009253 (1), R01DA018079 (1)