13 completed. 13 Phase 2, 4 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 13 |
| Phase 3 | 4 | Completed 4 |
| Phase 1 | 2 | Completed 2 |
Follow Tobacco Dependence: new trials by email Literature Review of Tobacco Dependence trials Research Report on Tobacco Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CO Monitoring for Tobacco Cessation in Quitlines Quitline Treatment as Usual (TAU), Remote Carbon Monoxide (CO) Monitoring, Incentivized Remote CO Monitoring - Tobacco Dependence | Phase 1 / Phase 2 | Completed | Consumer Wellness Solutions | 229 | 2021-12-31 | 2024-10-28 |
| UW Withdraw From Tobacco Study Combination nicotine replacement therapy (Nicotine patch + nicotine mini-lozenge) - Tobacco Dependence | Phase 2 | Completed | University of Wisconsin, Madison | 232 | 2021-07-13 | 2025-05-08 |
| Very Low Nicotine Cigarettes in Smokers With Schizophrenia Very low nicotine content cigarettes, standard nicotine content cigarettes - Tobacco Dependence | Phase 2 | Completed | Brown University | 58 | 2014-11-17 | 2018-04-09 |
| Acute Effects of Exercise in Smokers With Schizophrenia Exercise, passive control - Tobacco Dependence, Cigarette Craving | Phase 2 | Completed | Brown University | 30 | 2012-06-01 | 2015-09-28 |
| Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV Web-Based Tailored Smoking Cessation Intervention, Standard of Care - Tobacco Use Cessation, Tobacco Cessation | Phase 1 / Phase 2 | Completed | Georgetown University | 138 | 2011-09-01 | 2014-05-12 |
| Varenicline Treatment for Active Alcoholic Smokers Varenicline, placebo - Smoking, Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 33 | 2011-06-01 | 2018-02-05 |
| Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation Varenicline, Nicotine Patch, Varenicline and Placebo Patch - Tobacco Dependence | Phase 2 | Completed | University of Stellenbosch | 446 | 2011-04-01 | 2014-03-26 |
| Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction nicotine lozenges, tobacco-free snuff - Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 81 | 2009-01-01 | 2013-09-13 |
| S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence S-Adenosyl-L-Methionine, placebo - Tobacco Dependence | Phase 2 / Phase 3 | Completed | Mayo Clinic | 150 | 2008-09-01 | 2011-09-09 |
| Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine Nicotine free cigarettes, Extra-low nicotine cigarettes, Nicotine Lozenge - Tobacco Dependence | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 66 | 2005-03-01 | 2017-01-16 |
| Effects of Naltrexone on Nicotine Reinforcement Naltrexone, Placebo - Tobacco Dependence | Phase 2 | Completed | University of Pennsylvania | 64 | 2004-03-01 | 2013-12-10 |
| Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence Nicotine Patch, Nicotine Gum - Tobacco Dependence | Phase 2 / Phase 3 | Completed | National Institute on Drug Abuse (NIDA) | 157 | 1999-08-01 | 2017-01-12 |
| Provider and Peer Delivered Youth Smoking Intervention Pediatric Practice-Based Smoking Intervention - Tobacco Dependence | Phase 2 | Completed | University of Massachusetts, Worcester | 2711 | 1999-02-01 | 2007-02-14 |
Tobacco Use Disorder (13) · Smoking (4) · Smoking Cessation (2) · Tobacco Use (2) · Tobacco Use Cessation (2) · Acquired Immunodeficiency Syndrome (1) · Alcoholism (1) · Harm Reduction (1)
Chemically-Induced Disorders (13) · Mental Disorders (13) · Substance-Related Disorders (13) · Behavior (9) · Health Behavior (4) · Alcohol-Related Disorders (1) · Blood-Borne Infections (1) · Communicable Diseases (1) · Genital Diseases (1) · HIV Infections (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1) · Infections (1) · Lentivirus Infections (1) · RNA Virus Infections (1)
Tobacco Use Cessation Devices (5) · Nicotine Chewing Gum (2) · Sugars (2) · Varenicline (2) · Exercise (1) · Naltrexone (1) · Nicotine (1) · S-Adenosylmethionine (1) · Standard of Care (1)
Mayo Clinic (3) · Brown University (2) · National Institute on Drug Abuse (NIDA) (2) · Consumer Wellness Solutions (1) · Georgetown University (1) · University of Massachusetts, Worcester (1) · University of Pennsylvania (1) · University of Stellenbosch (1) · University of Wisconsin, Madison (1)
United States (12) · South Africa (1)
Jennifer Tidey, Ph.D. (2) · Amit Sood, M.D. (1) · Caryn Lerman, Ph.D. (1) · Dorohty Hatsukami, Ph.D. (1) · Elvis M Irusen, MBChB, FCP, PhD (1) · Eric T. Moolchan, M.D. (1) · Jesse T Kaye, PhD (1) · Jon O Ebbert, MD (1) · Kelly Carpenter, PhD (1) · Lori Pbert, Ph.D. (1) · Richard D. Hurt, MD (1) · Timothy B Baker, PhD (1)
PMID 37142273, PMID 16960700, PMID 18381502, PMID 20078491, PMID 23454876, PMID 25005652, PMID 25118794, PMID 25192771, PMID 27215559, PMID 29324248, PMID 37230961, PMID 42606856, PMID 42752171
R01DA017555 (1), R01HL109031 (1), R21CA163100 (1)