3 not yet recruiting, 2 completed, 1 terminated, 1 unknown. 7 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Not yet recruiting 3, Completed 2, Terminated 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
Follow Thrombotic Stroke: new trials by email Literature Review of Thrombotic Stroke trials Research Report on Thrombotic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT) Isosorbide Mononitrate, Butylphthalide, Isosorbide Mononitrate Placebo - Stroke, Lacunar, Stroke, Acute Ischemic | Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 3156 | 2025-12-01 | 2025-11-26 |
| CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioN carbogen with or without phenyleprhine, phenylephrine - Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Yonsei University | 40 | 2025-02-01 | 2025-01-20 |
| MLC1501 Study Assessing Efficacy in STROke Recovery MLC1501, Placebo - Stroke, Stroke, Ischemic | Phase 2 / Phase 3 | Not yet recruiting | Moleac Pte Ltd. | 540 | 2025-01-01 | 2023-03-16 |
| Cerebroprotective Effect of Melatonin in Stroke Melatonin 10 MG, Placebo - Stroke, Acute Ischemic, Strokes Thrombotic | Phase 3 | Unknown | Coordinación de Investigación en Salud, Mexico | 100 | 2024-03-01 | 2024-03-05 |
| Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study) carbogen, phenylephrine - Acute Ischemic Stroke | Phase 3 | Terminated | Yonsei University | 3 | 2021-04-05 | 2025-01-14 |
| LACunar Intervention (LACI-2) Trial-2 Isosorbide Mononitrate XL (ISMN), Cilostazol, ISMN XL and Cilostazol - Cerebral Small Vessel Diseases, Stroke, Lacunar | Phase 2 / Phase 3 | Completed | University of Edinburgh | 363 | 2018-01-08 | 2024-11-12 |
| Secondary Prevention of Small Subcortical Strokes Trial aspirin, clopidogrel, Target of Blood Pressure - Cerebrovascular Accident, Hypertension | Phase 3 | Completed | University of British Columbia | 3020 | 2003-02-01 | 2013-04-04 |
Ischemic Stroke (5) · Stroke, Lacunar (5) · Cerebral Small Vessel Diseases (2) · Stroke (2) · Alzheimer Disease (1) · Dementia (1) · Embolic Stroke (1) · Hypertension (1) · Myocardial Infarction (1)
Brain Diseases (7) · Cardiovascular Diseases (7) · Central Nervous System Diseases (7) · Cerebrovascular Disorders (7) · Nervous System Diseases (7) · Vascular Diseases (7) · Infarction (6) · Ischemia (6) · Necrosis (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Brain Infarction (5) · Stroke (5) · Cerebral Small Vessel Diseases (3)
Phenylephrine (2) · carbogen (2) · 3-n-butylphthalide (1) · Aspirin (1) · Cilostazol (1) · Clopidogrel (1) · Melatonin (1) · isosorbide-5-mononitrate (1)
Yonsei University (2) · Beijing Tiantan Hospital (1) · Coordinación de Investigación en Salud, Mexico (1) · Moleac Pte Ltd. (1) · University of British Columbia (1) · University of Edinburgh (1)
Mexico (2) · South Korea (2) · Canada (1) · Chile (1) · Ecuador (1) · Peru (1) · Spain (1) · United Kingdom (1) · United States (1)
Christopher Chen, BMBCh, MRCP, FAMS, FRCPE (1) · Hyo Suk Nam, MD, PhD (1) · Joanna M Wardlaw, MB ChB (1) · Oscar Benavente, M.D. (1) · Robert Hart, M.D. (1) · Yilong Wang (1)
PMID 20446946, PMID 21371282, PMID 21899409, PMID 22499292, PMID 22750086, PMID 22826359, PMID 22931315, PMID 23034910, PMID 23726159, PMID 23736109, PMID 24177006, PMID 24523037, PMID 24661819, PMID 24862645, PMID 25034716, PMID 25158772, PMID 25190442, PMID 25452300, PMID 25453457, PMID 26019129, PMID 26553236, PMID 26762524, PMID 26888535, PMID 26956031, PMID 28351962, PMID 30686103, PMID 31423869, PMID 32371759, PMID 32905623, PMID 33481011, PMID 35114798, PMID 35224730, PMID 35833913, PMID 36398903, PMID 36876480, PMID 37222252, PMID 38214239
2016 (1)