20 completed, 6 unknown, 3 recruiting, 3 terminated. 14 Not applicable, 7 Phase 4, 6 Phase 3, 2 Phase 2, 1 Phase 1.
Follow Surgical Blood Loss: new trials by email Literature Review of Surgical Blood Loss trials Research Report on Surgical Blood Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss Thromboelastography (TEG), Anesthesia Provider Survey - Surgical Blood Loss, Surgical Hemorrhage | Not applicable | Not yet recruiting | Boston Children's Hospital | 60 | 2027-01-01 | 2026-08-14 |
| Hemocoll, Avitene, or Bone Wax for Cancellous Bone Bleeding After Single-Ray Amputation Hemocoll® Fibrillar type-I collagen haemostat, Bone wax, Avitene™ Microfibrillar Collagen Hemostat - Hemostasis, Surgical Blood Loss | Not applicable | Recruiting | Adichunchanagiri Institute of Medical Sciences, B G Nagara | 135 | 2026-09-05 | 2026-10-27 |
| PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery. Periarticular vasoconstrictor infiltration (PVI), Erector Spinae Block (ESP) - Surgical Blood Loss, Postoperative Pain | Not applicable | Recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 62 | 2026-01-08 | 2026-04-24 |
| Usability of Pericardial Flushing with the Haermonics Pure System After Cardiac Surgery Haermonics Pure system - Surgical Blood Loss, Surgical Complication | Not applicable | Not yet recruiting | Haermonics BV | 65 | 2025-10-01 | 2025-03-14 |
| Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy Tranexamic acid, Normal Saline - Kidney Stones, Surgical Blood Loss | Phase 4 | Completed | Benha University | 90 | 2025-06-30 | 2026-10-30 |
| Decreasing Postoperative Blood Loss and Seizures by Timing of Intravenous Tranexamic Acid 2 Pilot Trial Before CPB Tranexamic Acid, After CPB Tranexamic Acid, Before CPB Placebo - Bleeding, Surgical Blood Loss | Phase 3 | Unknown | Hamilton Health Sciences Corporation | 40 | 2025-01-01 | 2024-10-02 |
| Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery Tranexamic Acid, Placebo - Surgical Blood Loss, Transfusion-dependent Anemia | Phase 3 | Completed | Ulrich Ronellenfitsch, MD | 892 | 2024-06-17 | 2026-10-07 |
| The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery Tranexamic acid, Placebo - Eyelid Diseases, Periorbital Disorder | Phase 4 | Withdrawn | University of Miami | 2023-09-01 | 2023-09-21 | |
| Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness FibCLOT, RiaSTAP - Hypofibrinogenemia, Surgical Blood Loss | Phase 2 | Completed | IRCCS Policlinico S. Donato | 40 | 2023-03-20 | 2024-02-28 |
| Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation - Tumor of Pancreas, Surgical Blood Loss | Not applicable | Recruiting | Zhejiang University | 30 | 2023-03-01 | 2025-06-02 |
| Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery Tranexamic Acid 100 MG/ML, normal saline - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | Universitas Indonesia | 132 | 2022-10-01 | 2023-02-01 |
| EtCO2 Level to Control Intraoperative Bleeding and Improve the Quality of Surgical Field Vision in Septorhinoplasty The amount of intraoperative bleeding, Quality of the intraoperative surgical field, Surgeon Satisfaction - Anesthesia, Carbon Dioxide | Not applicable | Completed | Bezmialem Vakif University | 70 | 2022-08-20 | 2023-02-06 |
| Thrombin in Cardiac Surgery Thrombin, Hemostatic Disorder | Unknown | University Health Network, Toronto | 200 | 2022-08-10 | 2022-11-09 | |
| Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients Cold stored platelets in 100% plasma stored for 10-14 days, Room temperature stored platelets in 100% plasma stored for up to 7 days - Hemorrhage, Platelets; Defect | Phase 1 / Phase 2 | Unknown | Moritz Stolla, MD | 30 | 2022-02-21 | 2023-07-27 |
| The Cryopreserved vs. Liquid Platelets Trial Cryopreserved platelets, Liquid-stored platelets - Surgical Blood Loss, Hemorrhage | Phase 3 | Active not recruiting | Australian and New Zealand Intensive Care Research Centre | 388 | 2021-08-17 | 2025-01-03 |
| Clinical Investigation Evaluating a New Autotransfusion Device in Cardiac Surgery i-SEP autotransfusion system - Hemorrhage, Blood Loss | Not applicable | Completed | i-SEP | 50 | 2020-09-28 | 2021-11-15 |
| Measurement of Blood Volume Loss During Burn Surgery Burn surgery, Measurement of RBC volume, plasma volume, and total blood volume using Daxor BVA-100 - Surgical Blood Loss, Burns | Withdrawn | Virginia Commonwealth University | 2020-01-01 | 2024-10-15 | ||
| Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures Enoxaparin Injectable Product, Sodium chloride - Venous Thrombosis Deep (Limbs), Surgical Blood Loss | Phase 4 | Terminated | Valleywise Health | 6 | 2019-12-16 | 2024-04-24 |
| DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery Tranexamic Acid - Bleeding, Surgical Blood Loss | Phase 3 | Terminated | Population Health Research Institute | 3242 | 2019-09-17 | 2026-10-26 |
| Patient Blood Management in Cardiac Surgery Iron and vitamin Deficiencies Correction Program, PBMi: Training program to improve transfusion practices - Surgical Blood Loss | Not applicable | Completed | Clinique Pasteur | 900 | 2019-09-10 | 2026-03-06 |
Showing 20 of 37. Sign in to see all of them.
Blood Loss, Surgical (37) · Hemorrhage (13) · Postoperative Hemorrhage (5) · Anemia (2) · Postoperative Complications (2) · Seizures (2) · Wounds and Injuries (2) · Afibrinogenemia (1) · Blood Platelet Disorders (1) · Body Weight (1) · Burns (1) · Coitus (1) · Colonic Neoplasms (1) · Coronary Artery Disease (1) · Eyelid Diseases (1)
Intraoperative Complications (37) · Pathologic Processes (37) · Pathological Conditions, Signs and Symptoms (37) · Hemorrhage (24) · Hemic and Lymphatic Diseases (6) · Postoperative Complications (6) · Hematologic Diseases (5) · Cardiovascular Diseases (4) · Signs and Symptoms (4) · Neoplasms (3) · Neurologic Manifestations (3) · Vascular Diseases (3) · Wounds and Injuries (3) · Digestive System Diseases (2) · Digestive System Neoplasms (2)
Tranexamic Acid (10) · Saline Solution (4) · Sodium Chloride (3) · Fibrinogen (2) · Arterial Pressure (1) · Blood Coagulation Tests (1) · Blood Transfusion (1) · Enoxaparin (1) · Erythrocyte Indices (1) · Heart Rate (1) · Iron (1) · Oxygen Saturation (1) · Plasma Volume (1) · Remifentanil (1) · Thrombelastography (1)
Population Health Research Institute (2) · University Health Network, Toronto (2) · University of Miami (2) · Adichunchanagiri Institute of Medical Sciences, B G Nagara (1) · Ain Shams University (1) · Australian and New Zealand Intensive Care Research Centre (1) · Benha University (1) · Bezmialem Vakif University (1) · Boston Children's Hospital (1) · CSL Behring (1) · Clinique Pasteur (1) · Dr. Abdul Mohsen Ibrahim Al-Turki Clinic (1) · Etablissement Français du Sang (1) · Federal University of Minas Gerais (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1)
Canada (6) · United States (5) · Brazil (2) · China (2) · Czechia (2) · France (2) · Germany (2) · Italy (2) · Spain (2) · Australia (1) · Austria (1) · Denmark (1) · Egypt (1) · Finland (1) · India (1)
Andre Lamy, MD (2) · Ahmed Khairyy Makled, MD (1) · Amgad Said Abu-Gamra, MD (1) · Andre Lamy, MD MHSc (1) · Bo Zhou, Dr. (1) · Eugene S. Krauss, MD (1) · Francis Gadrat, MD (1) · Hajer Giuma Soliman, M.B.B.CH (1) · Jean Wong, MD, FRCPC (1) · Justyna Bartoszko, MD MSc FRCPC (1) · Keyvan Karkouti, MD MSc FRCPC (1)
PMID 30908754, PMID 16438759, PMID 17218108, PMID 18480196, PMID 19926634, PMID 22054656, PMID 23381612, PMID 23717228, PMID 25265109, PMID 26280080, PMID 26337246, PMID 26524933, PMID 27317703, PMID 27774838, PMID 27807857, PMID 28902659, PMID 29224239, PMID 30146969, PMID 30462259, PMID 30611343, PMID 31044414, PMID 32695923, PMID 36600425, PMID 37294939, PMID 37407709, PMID 38587333, PMID 39146724, PMID 39383100, PMID 39425234, PMID 41360717, PMID 41483954
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