4 completed, 1 terminated, 1 unknown, 1 withdrawn. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 4, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Surgical Blood Loss: new trials by email Literature Review of Surgical Blood Loss trials Research Report on Surgical Blood Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy Tranexamic acid, Normal Saline - Kidney Stones, Surgical Blood Loss | Phase 4 | Completed | Benha University | 90 | 2025-06-30 | 2026-10-30 |
| The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery Tranexamic acid, Placebo - Eyelid Diseases, Periorbital Disorder | Phase 4 | Withdrawn | University of Miami | 2023-09-01 | 2023-09-21 | |
| Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery Tranexamic Acid 100 MG/ML, normal saline - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | Universitas Indonesia | 132 | 2022-10-01 | 2023-02-01 |
| Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures Enoxaparin Injectable Product, Sodium chloride - Venous Thrombosis Deep (Limbs), Surgical Blood Loss | Phase 4 | Terminated | Valleywise Health | 6 | 2019-12-16 | 2024-04-24 |
| Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery Tranexamic Acid - Bleeding, Surgical Blood Loss | Phase 4 | Completed | Population Health Research Institute | 97 | 2017-12-21 | 2021-02-11 |
| Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures Tranexamic Acid, Placebo - Hip Fractures, Surgical Blood Loss | Phase 4 | Unknown | Good Samaritan Regional Medical Center, Oregon | 100 | 2015-06-01 | 2015-10-29 |
| Topical Tranexamic Acid for Total Knee Arthroplasty tranexamic acid, Placebo - Surgical Blood Loss, Total Knee Arthroplasty | Phase 4 | Completed | University Health Network, Toronto | 125 | 2007-09-01 | 2011-04-11 |
Blood Loss, Surgical (7) · Hemorrhage (4) · Coronary Artery Disease (1) · Eyelid Diseases (1) · Heart Valve Diseases (1) · Hip Fractures (1) · Kidney Calculi (1) · Nephrolithiasis (1) · Postoperative Hemorrhage (1) · Venous Thrombosis (1)
Intraoperative Complications (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Hemorrhage (3) · Cardiovascular Diseases (2) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Calculi (1) · Coronary Disease (1) · Embolism and Thrombosis (1) · Eye Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Femoral Fractures (1)
Tranexamic Acid (6) · Saline Solution (3) · Enoxaparin (1) · Sodium Chloride (1)
Benha University (1) · Good Samaritan Regional Medical Center, Oregon (1) · Population Health Research Institute (1) · Universitas Indonesia (1) · University Health Network, Toronto (1) · University of Miami (1) · Valleywise Health (1)
Canada (2) · United States (2) · Egypt (1) · Indonesia (1)
Andre Lamy, MD MHSc (1) · Jean Wong, MD, FRCPC (1) · Thomas Wertin, MD, FACS (1) · Wendy W Lee, MD (1)
PMID 16438759, PMID 17218108, PMID 19926634, PMID 23381612, PMID 23717228, PMID 25265109, PMID 30908754