35 completed, 4 terminated, 3 unknown, 2 recruiting. 44 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 44 | Completed 35, Terminated 4, Unknown 3, Recruiting 2 |
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
Follow Staphylococcal Infections: new trials by email Literature Review of Staphylococcal Infections trials Research Report on Staphylococcal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis Rifampin-free regimen, Rifampin containing regimen - Infective Endocarditis | Phase 3 | Recruiting | Nantes University Hospital | 422 | 2026-06-11 | 2026-10-21 |
| Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections nasal antimicrobial photodisinfection therapy - Surgical Site Infections, Surgical Wound Infection | Phase 3 | Completed | Ondine Biomedical Inc. | 4787 | 2024-12-27 | 2026-09-15 |
| Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid, IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline - Staphylococcus Aureus Bacteremia | Phase 3 | Unknown | Clinical Research Centre, Malaysia | 290 | 2024-06-28 | 2024-07-05 |
| Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus Dalbavancin administration, Standard antibiotic therapy - Catheter Bacteremia, Staphylococcus Aureus Infection | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 406 | 2023-06-23 | 2025-04-06 |
| A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 Suvratoxumab, Placebo - Ventilator Associated Pneumonia, Staphylococcus Aureus | Phase 3 | Terminated | Aridis Pharmaceuticals, Inc. | 24 | 2022-09-02 | 2025-03-24 |
| Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 AR-301, Placebo - Lung Infection, Pneumonia, Ventilator-Associated | Phase 3 | Completed | Aridis Pharmaceuticals, Inc. | 174 | 2019-05-03 | 2023-07-06 |
| Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia Ceftobiprole medocaril, Daptomycin - Staphylococcus Aureus Bacteremia | Phase 3 | Completed | Basilea Pharmaceutica | 390 | 2018-08-26 | 2026-10-07 |
| Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA Dalbavancin, Vancomycin, Oxacillin - Methicillin-Resistant Staphylococcus Aureus, Bacterial Infections | Phase 3 | Completed | AbbVie | 199 | 2017-03-30 | 2024-09-19 |
| A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial Telavancin, Vancomycin, Daptomycin - Bacteremia | Phase 3 | Terminated | Cumberland Pharmaceuticals | 121 | 2014-12-01 | 2020-02-17 |
| Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo Ozenoxacin, Placebo - Impetigo | Phase 3 | Completed | Ferrer Internacional S.A. | 412 | 2014-06-01 | 2024-08-20 |
| Safety and Efficacy of Mupirocin Gel in Children With Impetigo Mupirocin gel, Mupirocin ointment, Placebo - Impetigo | Phase 3 | Completed | Reig Jofre Group | 467 | 2014-02-01 | 2021-03-12 |
| Staphylococcus Aureus Bacteremia Antibiotic Treatment Options Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid - Staphylococcus Aureus Infection | Phase 3 | Completed | Heinrich-Heine University, Duesseldorf | 215 | 2013-12-01 | 2020-05-27 |
| Vehicle Controlled Efficacy and Safety Study of Two Dose Regimens of CD07223 1.5% Topical Gel in Impetigo Experimental: CD07223 1.5 % Topical Gel BID, Experimental: CD07223 1.5% Topical Gel TID, Placebo Comparator: CD07223 vehicle gel BID - Impetigo | Phase 2 / Phase 3 | Completed | NovaBay Pharmaceuticals, Inc. | 328 | 2012-08-01 | 2014-08-12 |
| Citriodiol® and Impetigo p-menthane-3,8-diol oil - Impetigo | Phase 2 / Phase 3 | Unknown | Royal North Shore Hospital | 30 | 2012-07-01 | 2012-06-20 |
| Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo ozenoxacin placebo, retapamulin 1% ointment, ozenoxacin 1% cream - Impetigo | Phase 3 | Completed | Ferrer Internacional S.A. | 465 | 2012-03-01 | 2016-07-01 |
| Efficacy and Safety Study of Adalimumab in Treatment of Hidradenitis Suppurativa adalimumab, placebo - Hidradenitis Suppurativa (HS) | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 307 | 2011-11-01 | 2021-07-07 |
| Efficacy and Safety Study of Adalimumab in the Treatment of Hidradenitis Suppurativa adalimumab, placebo - Hidradenitis Suppurativa (HS) | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 326 | 2011-11-01 | 2021-07-12 |
| Vitamin D and Staphylococcus Aureus in the Diabetes Study cholecalciferol - Infection | Phase 3 | Completed | University of Tromso | 280 | 2011-04-01 | 2012-09-05 |
| Open and Comparative Study to Measure Tolerability and Efficacy of Taro Elixir oxytetracycline, taro elixir, Taro Elixir - Acne Vulgaris II or III Degree, Boils | Phase 3 | Unknown | Laboratorios Goulart S.A. | 120 | 2010-05-01 | 2010-03-19 |
| Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA Retpamulin Ointment, 1%, Linezolid - Skin Infections, Bacterial | Phase 3 | Completed | Stiefel, a GSK Company | 410 | 2009-04-01 | 2017-03-27 |
Showing 20 of 44. Sign in to see all of them.
Impetigo (8) · Staphylococcal Skin Infections (7) · Bacteremia (5) · Bacterial Infections (5) · Cellulitis (5) · Skin Diseases, Bacterial (4) · Surgical Wound Infection (4) · Acne Vulgaris (3) · Furunculosis (3) · Infections (3) · Kidney Failure, Chronic (3) · Pneumonia, Ventilator-Associated (3) · Sepsis (3) · Abscess (2)
Bacterial Infections and Mycoses (44) · Gram-Positive Bacterial Infections (42) · Infections (41) · Bacterial Infections (39) · Pathologic Processes (20) · Pathological Conditions, Signs and Symptoms (20) · Skin and Connective Tissue Diseases (19) · Skin Diseases (18) · Skin Diseases, Infectious (17) · Skin Diseases, Bacterial (14) · Inflammation (12) · Staphylococcal Skin Infections (11) · Streptococcal Infections (8) · Disease Attributes (7)
Vancomycin (11) · Daptomycin (6) · Clindamycin (4) · StaphVax (4) · Trimethoprim, Sulfamethoxazole Drug Combination (4) · Cefazolin (3) · Ceftaroline (3) · Cloxacillin (3) · Linezolid (3) · ceftobiprole medocaril (3) · telavancin (3) · Adalimumab (2) · Aztreonam (2) · Floxacillin (2) · Mupirocin (2)
Nabi Biopharmaceuticals (7) · Basilea Pharmaceutica (3) · Cumberland Pharmaceuticals (3) · AbbVie (prior sponsor, Abbott) (2) · Aridis Pharmaceuticals, Inc. (2) · Ferrer Internacional S.A. (2) · Forest Laboratories (2) · GlaxoSmithKline (2) · Merck Sharp & Dohme LLC (2) · AbbVie (1) · Assistance Publique - Hôpitaux de Paris (1) · Clinical Research Centre, Malaysia (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Heinrich-Heine University, Duesseldorf (1) · Laboratorios Goulart S.A. (1)
United States (18) · Mexico (7) · France (6) · Germany (6) · South Africa (6) · Spain (6) · Brazil (5) · Russia (5) · Ukraine (5) · Argentina (4) · Israel (4) · Netherlands (4) · Poland (4) · United Kingdom (4) · Chile (3)
Matt Hohenboken, MD, PhD (5) · G. Ralph Corey, MD (2) · Preston Holley, MD (2) · Achim J Kaasch, MD (1) · Andrea Gerbase (1) · Carlos Machado (1) · David Williams, MD (1) · Denise Steiner (1)
PMID 18444791, PMID 19095213, PMID 20695801, PMID 21115456, PMID 22416054, PMID 27518661, PMID 29380251, PMID 30365584, PMID 30597021, PMID 30716446, PMID 34741280, PMID 34922058, PMID 39141589, PMID 16914701, PMID 18225981, PMID 19118117, PMID 19799842, PMID 20462352, PMID 21115454, PMID 21115455, PMID 21444695, PMID 23085743, PMID 23549582, PMID 25396674, PMID 25483694, PMID 25977146, PMID 26072149, PMID 26452342, PMID 26962903, PMID 27025829, PMID 28535235, PMID 28987525, PMID 29898217, PMID 30926187, PMID 32051007, PMID 37754204, PMID 38244557
2014 (1)