5 unknown, 4 completed, 3 recruiting, 3 terminated. 15 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Unknown 5, Completed 4, Recruiting 3, Terminated 3 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
Follow Spinal Stenosis: new trials by email Literature Review of Spinal Stenosis trials Research Report on Spinal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Home-based Cycling for People With Lumbar Spinal Stenosis Home-based cycling program, usual care - Symptomatic Lumbar Spinal Stenosis | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 302 | 2025-02-10 | 2025-11-20 |
| Effect of Ketamine on Intraoperative Motor Evoked Potentials Ketamine - Spine Fusion, Spine Tumor | Phase 3 | Recruiting | University of California, San Francisco | 20 | 2023-12-01 | 2025-05-07 |
| Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo - Opioid Use, Lumbar Spinal Stenosis | Phase 3 | Recruiting | Hospital for Special Surgery, New York | 150 | 2021-11-05 | 2026-04-28 |
| Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection Teicoplanin - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 3 | Unknown | Bezmialem Vakif University | 120 | 2020-04-15 | 2020-04-14 |
| Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs Bone Marrow Concentrate - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Stem Cures | 80 | 2018-11-21 | 2020-09-22 |
| Thermographic Images as an Objective Method for Assessing the Efficacy of Steroidal Epidural Injections Therm-AppTM TH, thermographic camera, epidural injection - Spinal Stenosis | Phase 2 / Phase 3 | Unknown | Tel-Aviv Sourasky Medical Center | 40 | 2016-03-01 | 2016-04-01 |
| The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis i-FACTOR - Spinal Stenosis | Phase 3 | Unknown | Sygehus Lillebaelt | 108 | 2012-03-01 | 2016-09-07 |
| INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine INFUSE Bone Graft, Iliac Crest Bone Graft - Lumbar Spine Degeneration | Phase 3 | Terminated | Medtronic Spinal and Biologics | 15 | 2011-07-01 | 2016-02-18 |
| The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam s-ketamine & midazolam, Morphine PCA - Analgesia, Patient-controlled, Spinal Stenosis | Phase 2 / Phase 3 | Completed | University Hospital, Basel, Switzerland | 22 | 2011-01-01 | 2013-01-29 |
| A Study of the In-Space Device for Treatment of Moderate Spinal Stenosis Interspinous Spacer device, Interspinous Process Distraction Device - Spinal Stenosis | Phase 3 | Terminated | Synthes USA HQ, Inc. | 44 | 2008-06-01 | 2012-06-11 |
| Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis "TOPS System" - Total Posterior Arthroplasty Implant - Low Back Pain, Leg Pain | Phase 3 | Completed | Impliant, Ltd. | 450 | 2006-09-01 | 2011-05-18 |
| Total Facet Arthroplasty System®(TFAS®) Clinical Trial Total Facet Arthroplasty System® (TFAS®) - Spinal Stenosis, Low Back Pain | Phase 3 | Unknown | Archus Orthopedics, Inc. | 450 | 2005-08-01 | 2009-02-05 |
| A Clinical Study of the Dynesys(R) Spinal System Posterior Pedicle Screw System - Degenerative Spondylolisthesis or Retrolisthesis, Spinal Stenosis | Phase 3 | Terminated | Zimmer Biomet | 399 | 2003-03-01 | 2012-06-28 |
| Greenwich Lumbar Stenosis SLIP Study Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy - Spinal Stenosis, Spondylolisthesis | Phase 3 | Completed | Greenwich Hospital | 66 | 2002-05-01 | 2015-12-03 |
| Surgical Versus Nonsurgical Treatment for Spinal Stenosis Surgical decompression, Physical therapy - Spinal Stenosis | Phase 3 | Completed | University of Pittsburgh | 178 | 2000-09-01 | 2013-02-27 |
Spondylolisthesis (5) · Low Back Pain (4) · Intervertebral Disc Displacement (2) · Radiculopathy (2) · Spinal Diseases (2) · Agnosia (1) · Back Pain (1) · Intervertebral Disc Degeneration (1) · Pain, Postoperative (1) · Surgical Wound Infection (1)
Bone Diseases (15) · Musculoskeletal Diseases (15) · Spinal Diseases (13) · Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (6) · Signs and Symptoms (6) · Pain (5) · Spondylolysis (5) · Spondylosis (5) · Back Pain (4) · Nervous System Diseases (3) · Hernia (2) · Neuromuscular Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Anatomical (2)
Decompression, Surgical (1) · Esketamine (1) · Exercise (1) · Fibrinogen (1) · Foraminotomy (1) · Injections (1) · Injections, Epidural (1) · Ketamine (1) · Laminectomy (1) · Methylprednisolone Acetate (1) · Midazolam (1) · Physical Therapy Modalities (1) · Resistance Training (1) · Suspensions (1) · Teicoplanin (1)
Archus Orthopedics, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Bezmialem Vakif University (1) · Greenwich Hospital (1) · Hospital for Special Surgery, New York (1) · Impliant, Ltd. (1) · Medtronic Spinal and Biologics (1) · Stem Cures (1) · Sygehus Lillebaelt (1) · Synthes USA HQ, Inc. (1) · Tel-Aviv Sourasky Medical Center (1) · University Hospital, Basel, Switzerland (1) · University of California, San Francisco (1) · University of Pittsburgh (1) · Zimmer Biomet (1)
United States (9) · Denmark (1) · France (1) · Switzerland (1)
Anthony Delitto, PhD (1) · Christelle Nguyen, MD, PhD (1) · Edward C Benzel, MD (1) · Isabelle Boutron, MD, PhD (1) · Marc Buren, MD (1) · Michael K Jacobsen, MD (1) · Paul McAfee, M.D. (1) · Sairam Atluri, MD (1) · Wilhelm Ruppen, MD (1) · Zoher Ghogawala, MD (1)
PMID 23373567, PMID 25844995, PMID 26501698, PMID 27074067
R01AR045622 (1)