9 completed, 3 unknown, 1 enrolling by invitation, 1 withdrawn. 14 Phase 2, 5 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 9, Unknown 3, Enrolling by invitation 1, Withdrawn 1 |
| Phase 1 | 5 | Completed 4, Withdrawn 1 |
| Phase 3 | 3 | Unknown 2, Completed 1 |
Follow Spinal Stenosis: new trials by email Literature Review of Spinal Stenosis trials Research Report on Spinal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery oxytocin nasal spray - Cervical Spinal Stenosis, Thoracic Spinal Stenosis | Phase 2 | Completed | Zhejiang University | 227 | 2025-06-01 | 2026-08-20 |
| 124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome 124I-evuzamitide - Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS) | Phase 2 | Enrolling by invitation | University of Tennessee Graduate School of Medicine | 40 | 2025-05-22 | 2026-07-21 |
| Sterile Amniotic Fluid Filtrate Epidural Injection. Amniotic Fluid Allograft, Dexamethasone sodium phosphate - Lumbar Spinal Stenosis | Phase 1 / Phase 2 | Completed | University of Utah | 58 | 2021-06-16 | 2026-09-25 |
| Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine Liposomal bupivacaine - Lumbar Spinal Stenosis | Phase 2 | Unknown | University of Colorado, Denver | 100 | 2019-09-08 | 2024-10-01 |
| Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs Bone Marrow Concentrate - Low Back Pain, Disc Disease | Phase 2 / Phase 3 | Unknown | Stem Cures | 80 | 2018-11-21 | 2020-09-22 |
| Thermographic Images as an Objective Method for Assessing the Efficacy of Steroidal Epidural Injections Therm-AppTM TH, thermographic camera, epidural injection - Spinal Stenosis | Phase 2 / Phase 3 | Unknown | Tel-Aviv Sourasky Medical Center | 40 | 2016-03-01 | 2016-04-01 |
| Cognitive-Behavioral Physical Therapy CBPT, Control-Attention - Spinal Stenosis | Phase 1 / Phase 2 | Completed | Vanderbilt University | 86 | 2012-02-01 | 2014-07-04 |
| The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam s-ketamine & midazolam, Morphine PCA - Analgesia, Patient-controlled, Spinal Stenosis | Phase 2 / Phase 3 | Completed | University Hospital, Basel, Switzerland | 22 | 2011-01-01 | 2013-01-29 |
| Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion NeoFuse, MasterGraft Granules - Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Completed | Mesoblast, Ltd. | 12 | 2010-06-01 | 2020-06-29 |
| Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy NeoFuse, Allograft - Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 2 | Completed | Mesoblast, Ltd. | 24 | 2010-06-01 | 2019-08-16 |
| Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse - Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 2 | Completed | Mesoblast, Ltd. | 24 | 2009-09-01 | 2020-06-29 |
| Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion PLF with autograft, PLF with NeoFuse - Degenerative Disc Disease, Degenerative Spondylolisthesis | Phase 1 / Phase 2 | Withdrawn | Mesoblast, Ltd. | 2008-11-01 | 2020-06-02 | |
| Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) NeoFuse, posterolateral spinal fusion with instrumentation - Degenerative Disc Disease, Spondylolisthesis | Phase 1 / Phase 2 | Completed | Mesoblast, Ltd. | 6 | 2007-10-01 | 2020-06-29 |
| Chiropractic Dosage for Lumbar Stenosis flexion distraction, placebo control - Lumbar Spinal Stenosis | Phase 2 | Completed | National University of Health Sciences | 60 | 2007-09-01 | 2011-10-12 |
Intervertebral Disc Degeneration (4) · Spondylolisthesis (3) · Agnosia (1) · Amyloid Neuropathies, Familial (1) · Amyloidosis (1) · Carpal Tunnel Syndrome (1) · Emergence Delirium (1) · Low Back Pain (1) · Radiculopathy (1) · Rotator Cuff Injuries (1)
Bone Diseases (14) · Musculoskeletal Diseases (14) · Spinal Diseases (14) · Nervous System Diseases (4) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Spondylolysis (3) · Spondylosis (3) · Neurobehavioral Manifestations (2) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Wounds and Injuries (2) · Amyloid Neuropathies (1) · Amyloidosis, Familial (1)
Spinal Fusion (3) · Gene Fusion (2) · Transplantation, Autologous (2) · Dexamethasone (1) · Esketamine (1) · Injections, Epidural (1) · Midazolam (1) · Transplantation, Homologous (1) · dexamethasone 21-phosphate (1)
Mesoblast, Ltd. (5) · National University of Health Sciences (1) · Stem Cures (1) · Tel-Aviv Sourasky Medical Center (1) · University Hospital, Basel, Switzerland (1) · University of Colorado, Denver (1) · University of Tennessee Graduate School of Medicine (1) · University of Utah (1) · Vanderbilt University (1) · Zhejiang University (1)
United States (10) · Australia (1) · China (1) · Switzerland (1)
Roger Brown (3) · Donna Skerrett, MD (2) · Emily B. Martin, PhD (1) · Jerrilyn Cambron, DC, PhD (1) · Kristin Archer, PhD (1) · Sairam Atluri, MD (1) · Wilhelm Ruppen, MD (1) · Zachary L McCormick, MD (1)
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