9 completed, 3 unknown, 2 active not recruiting, 2 withdrawn. 18 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 18 | Completed 9, Unknown 3, Active not recruiting 2, Withdrawn 2, Recruiting 1, Terminated 1 |
Follow Smoking Cessation: new trials by email Literature Review of Smoking Cessation trials Research Report on Smoking Cessation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing Empowering Smoking Cessation ECHO (Empowering Our Community & Health Outcomes) - Smoking Cessation | Early Phase 1 | Withdrawn | University of Oklahoma | 2026-08-01 | 2026-05-07 | |
| Smart Olfaction App to Reduce Relapse Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition - Nicotine Dependence | Early Phase 1 | Recruiting | University of Houston | 132 | 2026-04-22 | 2026-07-08 |
| Electronic Cigarettes and Nicotine Pouches for Smoking Cessation E-cigarettes device plus liquid, Nicotine Pouches, Basic care counseling about smoking cessation - Role of Tobacco Harm Reduction in Smoking Cessation, Efficiency and Efficacy of E-cigarettes and Nicotine Pouches | Early Phase 1 | Unknown | Alternative Research Initiative | 600 | 2023-12-01 | 2023-02-06 |
| Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan Nicotine patch, Nicotine gums, Brief Advice (5 A's & 5 R's), Nicotine Patch: Preloading for 4 weeks - Smoking Cessation, Smoking, Cigarette | Early Phase 1 | Unknown | Nazarbayev University | 200 | 2023-07-01 | 2023-03-24 |
| Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder Ketamine Hydrochloride, Motivational enhancement therapy - Tobacco Use, Smoking Cessation | Early Phase 1 | Completed | Medical University of South Carolina | 7 | 2023-05-02 | 2025-07-18 |
| Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation Isradipine, Cue Exposure - Nicotine Dependence, Smoking, Cigarette | Early Phase 1 | Completed | Jasper A. Smits | 78 | 2020-01-22 | 2026-06-15 |
| Smoking by IV Pulsed Nicotine Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s - Smoking Cessation | Early Phase 1 | Completed | Yale University | 13 | 2019-11-15 | 2021-07-20 |
| Health Literacy and Smoking Cessation in Low-SES Diverse Smokers - Project HALT II Questionnaire, In-Depth Interviews, Breath Test - Smoking Cessation | Early Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2018-12-14 | 2019-05-01 | |
| Hollings Cancer Center Varenicline Sampling Study Varenicline 0.5 MG - Smoking, Smoking Cessation | Early Phase 1 | Completed | Medical University of South Carolina | 99 | 2018-12-03 | 2020-10-28 |
| Applying mHealth to Tobacco-related Health Disparities Nicotine Patch, Counseling, Smartphone - Smoking Cessation | Early Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 50 | 2018-07-16 | 2023-05-11 |
| End Nicotine Dependence Clinic Group Counseling, Individual Counseling, Phone Counseling - Smoking Cessation | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 56 | 2018-01-09 | 2020-04-14 |
| Smoking Cessation Intervention During Low Dose CT (LDCT) Screening for Lung Cancer Questionnaires, Low Dose Computed Tomography Scan, Shared Decision Making + Video - Smoking Cessation | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 630 | 2017-06-16 | 2026-11-02 |
| Gut Hormones in Obesity, Nicotine and Alcohol Dependence Exenatide, Desacyl ghrelin, Saline - Obesity, Smoking Cessation | Early Phase 1 | Unknown | Imperial College London | 95 | 2015-08-01 | 2020-02-13 |
| Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence Varenicline, Counseling and Support Materials, Laboratory Assessments - Smoking Cessation, Tobacco Dependence | Early Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 86 | 2014-07-17 | 2020-11-27 |
| DPBRN Hygienists Internet Quality Improvement in Tobacco Cessation (HiQuit) Electronic Referral - Smoking Cessation | Early Phase 1 | Completed | Dental Practice-Based Research Network | 80 | 2010-04-01 | 2013-01-25 |
| Smoking Cessation Treatment for Head & Neck Cancer Patients Acceptance and Commitment Therapy, Motivational and Behavioral Counseling, Varenicline - Head and Neck Cancer, Smoking Cessation | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 51 | 2010-03-24 | 2026-06-15 |
| Smoking Cessation Treatment for Head and Neck Cancer Patients Varenicline (Chantix), Nicotine Patch - Smoking Cessation | Early Phase 1 | Terminated | Yale University | 7 | 2009-07-01 | 2013-07-15 |
| Pilot Study on Mindfulness for Tobacco and Alcohol in University Students Mindfulness Training for Smokers, Interactive Learning for Smokers - Nicotine Dependence, Alcohol Use | Early Phase 1 | Completed | University of Wisconsin, Madison | 55 | 2006-09-01 | 2014-06-24 |
Tobacco Use Disorder (6) · Smoking (4) · Cigarette Smoking (3) · Tobacco Use (2) · Alcohol Drinking (1) · Alcoholism (1) · Behavior, Addictive (1) · Head and Neck Neoplasms (1) · Neoplasms (1) · Obesity (1) · Smoking Reduction (1) · Substance-Related Disorders (1) · Tobacco Smoking (1) · Vaping (1)
Behavior (18) · Health Behavior (18) · Chemically-Induced Disorders (7) · Mental Disorders (7) · Substance-Related Disorders (6) · Tobacco Use (3) · Tobacco Smoking (2) · Alcohol-Related Disorders (1) · Body Weight (1) · Compulsive Behavior (1) · Drinking Behavior (1) · Impulsive Behavior (1) · Neoplasms by Site (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1)
Tobacco Use Cessation Devices (6) · Varenicline (4) · Counseling (3) · Nicotine (2) · Nicotine Replacement Therapy (2) · Surveys and Questionnaires (2) · Acceptance and Commitment Therapy (1) · Behavior Therapy (1) · Carbon Monoxide (1) · Control Groups (1) · Crisis Intervention (1) · Exenatide (1) · Fluid Therapy (1) · Isradipine (1) · Ketamine (1)
M.D. Anderson Cancer Center (3) · H. Lee Moffitt Cancer Center and Research Institute (2) · Medical University of South Carolina (2) · Yale University (2) · Alternative Research Initiative (1) · Case Comprehensive Cancer Center (1) · Dental Practice-Based Research Network (1) · Imperial College London (1) · Jasper A. Smits (1) · Nazarbayev University (1) · University of Houston (1) · University of Oklahoma (1) · University of Wisconsin, Madison (1)
United States (14) · Kazakhstan (1) · Pakistan (1) · United Kingdom (1)
Benjamin Toll, Ph.D. (1) · Cara C Young, Ph.D. (1) · Christine Vinci, Ph.D (1) · David Nutt, MD, PhD (1) · Diana S. Hoover, PHD (1) · Gregg H. GIlbert, DDS, MBA (1) · James M Davis, MD (1) · Jan Blalock, PhD (1) · Jason D Robinson, MD (1) · Jasper AJ Smits, Ph.D. (1) · Julia M McQuoid, PhD (1) · Lorra Garey, Ph.D. (1) · Mehmet Sofuoglu, M.D.,Ph.D. (1) · Michael Businelle, Ph.D. (1) · Michael Sayette, Ph.D. (1)
PMID 11717401, PMID 20884658, PMID 22320954, PMID 24006963, PMID 24139766, PMID 24439349, PMID 26284723, PMID 29486753, PMID 30932386, PMID 31241286, PMID 32578165, PMID 33249458, PMID 33605440, PMID 33625366, PMID 35420700, PMID 38011129, PMID 38167206, PMID 38789642, PMID 39804633, PMID 40106803, PMID 9583654, PMID 9725117
P50DA019706 (1), R00MD010468 (1), R01CA120153 (1), R21DA049539 (1), R34DA060534 (1), U01DE016747 (1)