13 unknown. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Unknown 13 |
Follow Sleep Initiation and Maintenance Disorders: new trials by email Literature Review of Sleep Initiation and Maintenance Disorders trials Research Report on Sleep Initiation and Maintenance Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Dolutegravir Compared With Darunavir/Cobicistat on the Severity of Neuropsychiatric Effects al 12 Weeks in Antirretroviral Treatment-Naive Adults. Dolutegravir (DTG), Darunavir/Cobicistat (FDC) - HIV, Insomnia | Phase 4 | Unknown | Instituto Mexicano del Seguro Social | 140 | 2025-06-19 | 2025-06-26 |
| Effects of Melissa Extract on Sleep Characteristics Melissa phytosome, Placebo - Sleep Disorder, Anxiety | Phase 4 | Unknown | University of Urbino "Carlo Bo" | 40 | 2023-09-01 | 2023-07-18 |
| Influence of Olfaction Essential Oils on the Consumption of Benzodiazepine Receptor Agonists & Z-Drugs (BZRAs) Prescribed as " if Needed " in Psychiatric Outpatients (HECBA-PSY). Essences and Essential Oils - Psychiatric Disorder, Benzodiazepine Withdrawal | Phase 4 | Unknown | Etablissement Public de Santé Barthélemy Durand | 50 | 2021-04-19 | 2022-10-18 |
| Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome) Xuefu-Zhuyu Capsule, placebo, conventional therapy - Chinese Medicine, Stable Coronary Heart Disease | Phase 4 | Unknown | Zhong Wang | 720 | 2019-12-31 | 2022-11-15 |
| Impact of Suvorexant on Sympathetic Nerve Activity and Baroreflex Function in Chronic Insomnia Suvorexant, Placebo - Chronic Insomnia | Phase 4 | Unknown | Montana State University | 34 | 2019-04-18 | 2021-10-07 |
| Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD Auricular point pressure therapy, Oral estazolam medication - Renal Dialysis, Sleep Initiation and Maintenance Disorders | Phase 4 | Unknown | The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine | 120 | 2019-03-01 | 2020-12-16 |
| The Effect of Twice Daily vs. Once Daily Bronchodilation on Hyperinflation in COPD Patients During 24 Hours. Tiotropium 'Respimat' 5 mcg, Aclidinium Bromide/Formoterol Fumarate 340/12 mcg - Chronic Obstructive Airway Disease | Phase 4 | Unknown | Maastricht University Medical Center | 49 | 2017-07-07 | 2020-03-10 |
| A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia suvorexant, Placebo - Depression, Major Depressive Disorder | Phase 4 | Unknown | Institute for Advanced Medical Research, Alpharetta, GA | 74 | 2017-03-01 | 2019-02-27 |
| Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Ramelteon, Placebo - Insomnia, Brain Injury | Phase 4 | Unknown | Kessler Foundation | 20 | 2010-09-01 | 2014-09-09 |
| Brain Mechanisms and Targeting Insomnia in Major Depression escitalopram and eszopiclone, Escitalopram, eszopiclone, and placebo, Escitalopram - Major Depressive Disorder, Insomnia | Phase 4 | Unknown | University of California, Los Angeles | 60 | 2008-05-01 | 2010-08-20 |
| Effects of Ramelteon (8mg) Alone and in Combination With Multi-Component Behavioral Therapy on Sleep and Circadian Phase in Patients With Chronic Insomnia Placebo, Rozerem 8mg, Rozerem 8mg in combination with Multi Component Behavior Therapy - Insomnia | Phase 4 | Unknown | University of Arizona | 30 | 2007-08-01 | 2010-08-12 |
| Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain Magnetic Sleep Pad - Back Pain, Neck Pain | Phase 4 | Unknown | Weintraub, Michael I., MD, FACP, FAAN | 80 | 2007-02-01 | 2007-09-27 |
| Effect of Atomoxetine on ADHD-Related Insomnia in Children and Adolescents atomoxetine - Attention-Deficit/Hyperactivity Disorder (ADHD), Insomnia | Phase 4 | Unknown | Rhode Island Hospital | 36 | 2005-11-01 | 2006-07-07 |
Anxiety Disorders (3) · Depression (2) · Depressive Disorder, Major (2) · Sleep Wake Disorders (2) · Anosmia (1) · Attention Deficit Disorder with Hyperactivity (1) · Back Pain (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Endometriosis (1) · Headache (1) · Mental Disorders (1) · Motor Activity (1) · Neck Pain (1)
Dyssomnias (13) · Nervous System Diseases (13) · Sleep Disorders, Intrinsic (13) · Mental Disorders (12) · Sleep Wake Disorders (11) · Pathological Conditions, Signs and Symptoms (6) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Behavior (3) · Behavioral Symptoms (2) · Depressive Disorder (2) · Mood Disorders (2) · Pain (2) · Attention Deficit and Disruptive Behavior Disorders (1) · Brain Diseases (1)
ramelteon (2) · suvorexant (2) · Atomoxetine Hydrochloride (1) · Cobicistat (1) · Darunavir (1) · Escitalopram (1) · Eszopiclone (1) · Formoterol Fumarate (1) · Oils, Volatile (1) · Sugars (1) · Xue-Fu-Zhu-Yu decoction (1) · aclidinium bromide (1) · dolutegravir (1)
Etablissement Public de Santé Barthélemy Durand (1) · Institute for Advanced Medical Research, Alpharetta, GA (1) · Instituto Mexicano del Seguro Social (1) · Kessler Foundation (1) · Maastricht University Medical Center (1) · Montana State University (1) · Rhode Island Hospital (1) · The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine (1) · University of Arizona (1) · University of California, Los Angeles (1) · University of Urbino "Carlo Bo" (1) · Weintraub, Michael I., MD, FACP, FAAN (1) · Zhong Wang (1)
United States (7) · China (2) · France (1) · Italy (1) · Netherlands (1)
Angelo Sambunaris, MD (1) · Anthony Lequerica, PhD (1) · Christian Trichard (1) · Ian A Cook, MD (1) · Jason Carter, PhD (1) · Judith Owens, MD, MPH (1) · Lowie Vanfleteren, MD, PhD (1) · Michael I. Weintraub, MD (1) · Qing-Quan Liu, Prof. (1) · Richard R Bootzin, PhD (1) · Zhong Wang, M.D. (1)