4 completed, 4 recruiting, 2 terminated, 1 active not recruiting. 8 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Recruiting 3, Active not recruiting 1 |
| Early Phase 1 | 1 | Terminated 1 |
Follow SIBO: new trials by email Literature Review of SIBO trials Research Report on SIBO
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Characterization of Small Intestinal Bacterial Overgrowth and Intestinal Barrier-Related Biomarkers in Patients With Severe Periodontitis: A Pilot Prospective Longitudinal Observational Cohort Study Periodontitis (Stage 3), Periodontitis Stage IV | Recruiting | Iuliu Hatieganu University of Medicine and Pharmacy | 20 | 2026-10-02 | 2026-10-30 | |
| Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy SIBO, Pancreatic Insufficiency | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2026-04-30 | 2026-04-13 | |
| The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions Probiotic Supplementation with L. reuteri - PARKINSON DISEASE (Disorder), Parkinson | Not applicable | Recruiting | University of Cambridge | 215 | 2025-11-01 | 2026-08-25 |
| Efficacy of Rifaximin in Patients With Small Intestinal Bacterial Overgrowth Presenting With Abdominal Bloating. Rifaximin (drug) - SIBO | Not applicable | Recruiting | Xiuli Zuo | 115 | 2025-04-15 | 2025-05-16 |
| The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms Probiotic - Small Intestinal Bacterial Overgrowth, SIBO | Not applicable | Active not recruiting | Nimble Science Ltd. | 105 | 2024-07-10 | 2026-09-30 |
| The Low FODMAP Diet in Individuals With Small Intestinal Bacterial Overgrowth (SIBO) Low FODMAP Diet, Healthy Eating Diet - SIBO, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Warsaw University of Life Sciences | 51 | 2024-02-08 | 2026-02-24 |
| The Efficacy of Probiotics as an Adjunct to Treatment of SIBO With Rifaximin Rifaximin (Xifaxan) 1200mg/day, Probiotic, XIFAXAN® (Rifaximin) 1600mg/day - Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth | Not applicable | Completed | Pomeranian Medical University Szczecin | 129 | 2023-04-01 | 2025-12-04 |
| Systems Biology of Gastrointestinal and Related Diseases Ulcerative Colitis, Crohn Disease | Terminated | Viome | 17 | 2022-11-11 | 2023-12-15 | |
| Effect of a Low FODMAP Diet on SIBO Breath Test Positivity low FODMAP diet - SIBO | Early Phase 1 | Terminated | Beth Israel Deaconess Medical Center | 14 | 2020-11-15 | 2025-07-04 |
| Clinical Utility of Handheld Hydrogen Breathalyzer in Identification of Food Sensitivities (AIRE Study) Hydrogen content recording - SIBO, Small Bowel Bacterial Overgrowth Syndrome | Not applicable | Completed | Johns Hopkins University | 45 | 2020-10-01 | 2025-05-28 |
| Atrantil for Intestinal Bacterial Overgrowth Atrantil (Medical Food) - Irritable Bowel Syndrome, Bacterial Overgrowth Syndrome | Not applicable | Completed | Northwestern University | 40 | 2020-09-18 | 2023-01-12 |
| Capillary Endoscopy Aspiration Catheter Capillary Endoscopy Aspiration Catheter, Endoscopy Aspiration Catheter - Microbiota, SIBO | Not applicable | Recruiting | Cedars-Sinai Medical Center | 46 | 2020-05-20 | 2026-01-26 |
Irritable Bowel Syndrome (4) · Gastrointestinal Diseases (2) · Alzheimer Disease (1) · Barrett Esophagus (1) · Blind Loop Syndrome (1) · Celiac Disease (1) · Cholelithiasis (1) · Cognitive Dysfunction (1) · Colitis, Lymphocytic (1) · Colitis, Microscopic (1) · Colitis, Ulcerative (1) · Colonic Polyps (1) · Constipation (1) · Crohn Disease (1) · Dementia (1)
Digestive System Diseases (5) · Colonic Diseases (4) · Colonic Diseases, Functional (4) · Intestinal Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Gastrointestinal Diseases (2) · Malabsorption Syndromes (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Anatomical (2) · Signs and Symptoms (2) · Basal Ganglia Diseases (1) · Biliary Tract Diseases (1) · Body Weight (1)
FODMAP Diet (2) · Probiotics (2) · Rifaximin (2) · Diet, Healthy (1) · Pharmaceutical Preparations (1)
Beth Israel Deaconess Medical Center (1) · Cedars-Sinai Medical Center (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Iuliu Hatieganu University of Medicine and Pharmacy (1) · Johns Hopkins University (1) · Nimble Science Ltd. (1) · Northwestern University (1) · Pomeranian Medical University Szczecin (1) · University of Cambridge (1) · Viome (1) · Warsaw University of Life Sciences (1) · Xiuli Zuo (1)
United States (5) · Poland (2) · Canada (1) · China (1) · Italy (1) · Romania (1) · United Kingdom (1)
Ali Rezaie, MD (1) · Anthony Lembo, M.D (1) · Caroline Williams-Gray, Dr. (1) · Darren Brenner, MD (1) · Enrico Celestino Nista (1) · Glenn Treisman, MD (1) · Katarzyna Kozlowska-Petriczko, MD, PhD (1) · Marta Camacho, Dr. (1) · Momchilo Vuyisich (1)