11 unknown. 11 Phase 1, 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Unknown 11 |
| Phase 2 | 9 | Unknown 9 |
Follow Shock: new trials by email Literature Review of Shock trials Research Report on Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG Normal saline, Dexmedetomidine, Methylprednisolone - Coronary Artery Disease, Systemic Inflammatory Response Syndrome | Phase 1 / Phase 2 | Unknown | Ain Shams University | 60 | 2025-09-01 | 2025-08-06 |
| Studying Topiramate for Re-Activating the HIV-1 Reservoir Topiramate - HIV-1-infection, Hiv | Phase 1 / Phase 2 | Unknown | Erasmus Medical Center | 12 | 2024-09-01 | 2024-02-28 |
| Optimizing Reversal of HIV Latency With Combination Therapy Panobinostat 20 MG Oral Capsule, Pyrimethamine 200mg Oral Tablet, Lenalidomide 25 MG Oral Capsule - Hiv | Phase 1 / Phase 2 | Unknown | Erasmus Medical Center | 49 | 2024-04-01 | 2024-02-05 |
| The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock Ondansetron, Placebo - Sepsis, Septic Shock | Phase 1 / Phase 2 | Unknown | Noha Mansour | 40 | 2022-04-24 | 2023-03-15 |
| Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients Albumin 20% and terlipressin - Septic Shock | Phase 1 | Unknown | Amany Mousa Salama Muhammed | 36 | 2021-10-01 | 2021-10-15 |
| High-dose Intravenous Vitamin C in Patients With Septic Shock Sodium Ascorbate - Sepsis, Severe, Septic Shock | Phase 1 | Unknown | Melbourne Health | 30 | 2021-09-27 | 2022-11-04 |
| Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients Collagen-Polyvinylpyrrolidone - Covid19, Cytokine Storm | Phase 1 / Phase 2 | Unknown | Janette Furuzawa Carballeda | 90 | 2020-08-19 | 2021-02-17 |
| Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells Metoprolol, metoprolol, infliximab, etanercept, tocilizumab and/or other agents - Solid Tumor, Hematological Malignancy | Phase 1 / Phase 2 | Unknown | Chinese PLA General Hospital | 30 | 2019-09-15 | 2022-04-13 |
| Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation. neostigmine methylsulfate，raceanisodamine hydrochloride - Systemic Inflammatory Response Syndrome, Jaundice, Obstructive | Phase 1 / Phase 2 | Unknown | Wanqing Gu | 100 | 2014-08-01 | 2014-10-30 |
| Using Human Menstrual Blood Cells to Treat Acute Lung Injury Caused by H7N9 Bird Flu Virus Infection Menstrual blood stem cells - Acute Lung Injury, Acute Respiratory Distress Syndrome (ARDS) | Phase 1 / Phase 2 | Unknown | S-Evans Biosciences Co., Ltd. | 20 | 2014-03-01 | 2014-03-24 |
| Russian Clinical Trial of Mesenchymal Cells in Patients With Septic Shock and Severe Neutropenia Mesenchymal stromal cells, Standard therapy of septic shock - Septic Shock, Nonchemotherapy Drug-induced Neutropenia | Phase 1 / Phase 2 | Unknown | National Research Center for Hematology, Russia | 30 | 2012-12-01 | 2013-05-10 |
Shock, Septic (4) · Acquired Immunodeficiency Syndrome (2) · Cytokine Release Syndrome (2) · Sepsis (2) · Systemic Inflammatory Response Syndrome (2) · Acute Lung Injury (1) · COVID-19 (1) · Coronary Artery Disease (1) · HIV Infections (1) · Hematologic Neoplasms (1) · Jaundice, Obstructive (1) · Multiple Organ Failure (1) · Neutropenia (1) · Postoperative Complications (1)
Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Inflammation (8) · Infections (7) · Systemic Inflammatory Response Syndrome (6) · RNA Virus Infections (3) · Virus Diseases (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Genital Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2)
Albumins (1) · Ascorbic Acid (1) · Control Groups (1) · Dexmedetomidine (1) · Etanercept (1) · Infliximab (1) · Lenalidomide (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Metoprolol (1) · Microcirculation (1) · Ondansetron (1) · Panobinostat (1) · Pyrimethamine (1) · Saline Solution (1)
Erasmus Medical Center (2) · Ain Shams University (1) · Amany Mousa Salama Muhammed (1) · Chinese PLA General Hospital (1) · Janette Furuzawa Carballeda (1) · Melbourne Health (1) · National Research Center for Hematology, Russia (1) · Noha Mansour (1) · S-Evans Biosciences Co., Ltd. (1) · Wanqing Gu (1)
China (3) · Egypt (2) · Netherlands (2) · Australia (1) · Mexico (1) · Russia (1)
Charlie Xiang, Doctor (1) · Daniel Azamar-Llamas, MD (1) · Eric Ochoa-Hein, MD (1) · Gennady M. Galstyan, MD PhD (1) · Gonzalo Torres-Villalobos, MD, PhD (1) · Janette Furuzawa-Carballeda, PhD (1) · Luis A Septien-Stute, MD (1) · Mark P Plummer, PhD (1)
PMID 10415784, PMID 12563677, PMID 14719037, PMID 15663512, PMID 17181919, PMID 18097874, PMID 19397687, PMID 19453649, PMID 19998041, PMID 21131395, PMID 22028728, PMID 22545014, PMID 22731679, PMID 26867177, PMID 28584818, PMID 30473697, PMID 31986264, PMID 32035018, PMID 32089354, PMID 32113509, PMID 32125455, PMID 32159775, PMID 32192578, PMID 32203186, PMID 32234467, PMID 32257537, PMID 32278362, PMID 32283152, PMID 32360286, PMID 32396163, PMID 9804346