9 completed, 6 unknown, 5 not yet recruiting, 2 terminated. 4 Not applicable, 4 Phase 2, 3 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Severe Preeclampsia: new trials by email Literature Review of Severe Preeclampsia trials Research Report on Severe Preeclampsia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Postpartum Furosemide in Recovery of Patients With Severe Preeclampsia Furosemide and Potassium, Placebo - Severe Preeclampsia | Not applicable | Recruiting | Lady Reading Hospital, Pakistan | 434 | 2026-10-01 | 2026-10-06 |
| Identification of Genes of Interest for Severe Forms of Preeclampsia Preeclampsia, Severe Preeclampsia | Not yet recruiting | University Hospital, Strasbourg, France | 100 | 2026-09-01 | 2026-07-14 | |
| Algorithm-Based Timing of Delivery Using the sFlt-1/PlGF Ratio in Early-Onset Severe Preeclampsia. (MAP 2 Study : Management Based on Angiogenic Markers in Preeclampsia 2 Study ) sFlt-1/PlGF ratio-guided management algorithm, Usual Care - Severe Preeclampsia | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 386 | 2026-07-01 | 2026-06-24 |
| Furosemide vs Placebo in Severe Preeclampsia Postpartum Furosemide, Folic Acid 5 MG - Severe Preeclampsia | Phase 2 | Not yet recruiting | Universidad Nacional Autonoma de Honduras | 186 | 2026-06-15 | 2026-06-15 |
| Factors Associated With Blood Pressure Control Failure to Intravenous Labetalol in Severe Preeclampsia Severe Preeclampsia | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 350 | 2026-04-01 | 2026-04-23 | |
| Levetiracetam Compared to Magnesium Sulfate for Prevention of Eclamptic Seizure Levetiracetam, magnesium sulfate - Severe Preeclampsia, Eclampsia Preeclampsia | Phase 3 | Not yet recruiting | Nebraska Methodist Health System | 1240 | 2026-01-01 | 2025-10-24 |
| Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women Arterial Blood gases - Preeclampsia, Severe Preeclampsia | Not applicable | Completed | Saint Thomas Hospital, Panama | 100 | 2025-08-15 | 2026-07-16 |
| Diastolic Dysfunction 2025 No Intervention (Observational Echocardiographic Evaluation) - Preeclampsia, Severe Preeclampsia | Completed | University Tunis El Manar | 80 | 2025-03-01 | 2025-09-24 | |
| Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia maintenance magnesium sulphate1g/h, maintenance magnesium sulphate2g/h - Severe Preeclampsia | Phase 1 / Phase 2 | Unknown | Ain Shams University | 100 | 2024-07-01 | 2024-07-03 |
| Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine Labetalol, Nitroglycerine, Nifedipine - Severe Preeclampsia | Not applicable | Unknown | Sohag University | 60 | 2024-03-30 | 2024-02-20 |
| Complement Regulation to Undo Systemic Harm in Preeclampsia Eculizumab - Preeclampsia, Severe Preeclampsia | Phase 2 | Terminated | Cedars-Sinai Medical Center | 2 | 2021-09-13 | 2023-11-29 |
| The Association Between Different Markers With Development of Maternal and Neonatal Complications in Women With Severe Preeclampsia Severe Preeclampsia | Completed | Cairo University | 284 | 2020-05-02 | 2025-08-27 | |
| Risk Prediction Models for Adverse Maternal and Neonatal Outcomes in Preeclampsia Observational - Severe Preeclampsia | Completed | Mpilo Central Hospital | 549 | 2018-11-12 | 2021-09-10 | |
| Serum Androgen Levels as a Marker for the Severity of Preeclampsia serum androgen levels - Severe Preeclampsia | Unknown | Ain Shams University | 75 | 2017-10-01 | 2018-11-20 | |
| Restless Leg Syndrome and Severe Preeclampsia Restless Leg Syndrome, Severe Preeclampsia | Completed | Saint Thomas Hospital, Panama | 310 | 2017-08-01 | 2018-01-04 | |
| Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Magnesium Sulfate - Severe Preeclampsia | Phase 4 | Completed | Assiut University | 222 | 2017-05-30 | 2020-04-24 |
| Study of the Efficacy and Safety of AMAG-423 (Digoxin Immune Fab) in Antepartum Subjects With Severe Preeclampsia AMAG-423 (digoxin immune fab), Placebo - Severe Preeclampsia | Phase 2 / Phase 3 | Terminated | AMAG Pharmaceuticals, Inc. | 58 | 2017-04-12 | 2026-05-22 |
| Antiphospholipid Antibodies and Early Severe Preeclampsia. Severe Preeclampsia, Antiphospholipid Syndrome | Unknown | Saint Thomas Hospital, Panama | 310 | 2015-06-01 | 2015-01-05 | |
| Pre-Eclampsia And Growth Restriction: a Longitudinal Study Preeclampsia, Severe Preeclampsia | Completed | CHU de Quebec-Universite Laval | 76 | 2015-03-01 | 2019-07-23 | |
| First-trimester Prediction of Preeclampsia Preeclampsia, Severe Preeclampsia | Completed | CHU de Quebec-Universite Laval | 7554 | 2014-11-01 | 2019-07-23 |
Showing 20 of 23. Sign in to see all of them.
Pre-Eclampsia (23) · Fetal Growth Retardation (2) · Hypertension, Pregnancy-Induced (2) · Premature Birth (2) · Antiphospholipid Syndrome (1) · Eclampsia (1) · HELLP Syndrome (1) · Hypertension (1) · Postpartum Hemorrhage (1) · Restless Legs Syndrome (1) · Seizures (1)
Female Urogenital Diseases and Pregnancy Complications (23) · Pregnancy Complications (23) · Urogenital Diseases (23) · Hypertension, Pregnancy-Induced (21) · Pathological Conditions, Signs and Symptoms (4) · Cardiovascular Diseases (3) · Obstetric Labor Complications (3) · Pathologic Processes (3) · Vascular Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Fetal Diseases (2) · Growth Disorders (2) · Hypertension (2) · Nervous System Diseases (2) · Obstetric Labor, Premature (2)
Magnesium Sulfate (3) · Furosemide (2) · Blood Gas Analysis (1) · Folic Acid (1) · Labetalol (1) · Levetiracetam (1) · Nifedipine (1) · Nitroglycerin (1) · Oxytocin (1) · Potassium (1) · Watchful Waiting (1) · carbetocin (1) · digoxin antibodies Fab fragments (1) · eculizumab (1)
Saint Thomas Hospital, Panama (4) · Ain Shams University (2) · CHU de Quebec-Universite Laval (2) · AMAG Pharmaceuticals, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Cairo University (1) · Cedars-Sinai Medical Center (1) · Hospital Clinic of Barcelona (1) · Instituto Materno Infantil Prof. Fernando Figueira (1) · Lady Reading Hospital, Pakistan (1) · Mpilo Central Hospital (1) · Nebraska Methodist Health System (1) · Sohag University (1) · Universidad Nacional Autonoma de Honduras (1)
Panama (4) · Egypt (3) · United States (3) · Canada (2) · Brazil (1) · France (1) · Honduras (1) · Pakistan (1) · Poland (1) · South Africa (1) · Spain (1) · Tunisia (1) · Turkey (Türkiye) (1) · Zimbabwe (1)
Osvaldo A Reyes, MD (3) · Emmanuel Bujold, MD, MSc (2) · Ahmed Maged, MD (1) · Dr Qandil Sattar (1) · Dr Syeda Wajeeha (1) · Francesc Figueras Retuerta, PhD (1) · Joseph A Ibrahiem, student (1) · Melania M Amorim, MD; PhD (1) · Osvaldo Reyes, MD (1) · Richard Burwick, MD, MPH (1) · Todd Lovgren, MD (1)
PMID 37815037, PMID 21098311, PMID 24890747, PMID 26597754, PMID 27037982, PMID 28906533, PMID 29957219, PMID 38708601