27 completed, 13 recruiting, 5 terminated, 5 unknown. 41 Not applicable, 4 Phase 2, 3 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Schizophrenia and Related Disorders: new trials by email Literature Review of Schizophrenia and Related Disorders trials Research Report on Schizophrenia and Related Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing a Virtual Reality-assisted Intervention for Emotion Regulation Difficulties in Psychosis MANOEUVRE therapy - Psychosis, SCHIZOPHRENIA 1 (Disorder) | Not applicable | Not yet recruiting | King's College London | 15 | 2027-09-01 | 2026-06-03 |
| Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India Community care for People with Schizophrenia in India (COPSI), mindLAMP Mobile Application - Schizophrenia, Schizophrenia and Related Disorders | Not applicable | Not yet recruiting | Harvard Medical School (HMS and HSDM) | 240 | 2026-10-01 | 2026-07-10 |
| Clay Therapy in Schizophrenia Patients Clay therapy - Schizophrenia and Related Disorders | Not applicable | Completed | Kutahya Health Sciences University | 17 | 2025-12-01 | 2026-07-28 |
| SPARK Healthy Sleep SPARK Healthy Sleep - Schizophrenia and Related Disorders, Sleep Disturbance | Not applicable | Recruiting | Indiana University | 115 | 2025-10-24 | 2026-07-07 |
| Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia Active rTMS stimulation, Sham rTMS stimulation - Schizophrenia and Related Disorders | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 120 | 2025-10-23 | 2026-08-05 |
| Tele-group Cognitive Behavioural Family Intervention for Individuals With Schizophrenia and Their Families (Definitive tgCBFI) tgCBFI programme, Treatment as Usual (TAU) - Schizophrenia and Related Disorders | Not applicable | Recruiting | The Hong Kong Polytechnic University | 200 | 2025-09-01 | 2026-07-24 |
| A Trial of Extended Reality Activities to Enhance Leisure Participation Among Inpatients With Persistent Mental Health Conditions XR-Based Leisure Intervention - Schizophrenia and Related Disorders, Mental Disorders | Not applicable | Not yet recruiting | Chia-Hui Hung | 25 | 2025-07-01 | 2025-05-09 |
| Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling LCHF Ketogenic Diet, Diet-as-Usual (DAU) - Schizophrenia, Schizophrenia and Related Disorders | Not applicable | Not yet recruiting | Stanford University | 120 | 2025-07-01 | 2025-05-16 |
| Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure Clozapine, Esketamine Nasal Product, Escitalopram - Schizophrenia and Related Disorders, Major Depressive Disorder | Phase 3 | Recruiting | Dr. Inge Winter | 1254 | 2025-04-27 | 2026-01-22 |
| Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment Active rTMS stimulation, Sham rTMS stimulation - Schizophrenia and Related Disorders | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 140 | 2025-02-01 | 2026-08-03 |
| Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS (R)-3-hydroxybutyl (R)-3-hydroxybutyrate), Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride - Schizophrenia and Related Disorders, Psychosis | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 28 | 2024-12-01 | 2026-04-27 |
| The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. Clozapine, Second-line Antipsychotics (treatment as usual) - Schizophrenia and Related Disorders, Early Treatment-Resistance | Phase 4 | Recruiting | Dr. Inge Winter | 418 | 2024-08-01 | 2025-09-26 |
| MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction MitoQ, Placebo - Schizophrenia and Related Disorders, Mitochondrial Alteration | Phase 2 / Phase 3 | Recruiting | Mclean Hospital | 100 | 2024-06-01 | 2025-09-25 |
| Social Isolation and Aging in Schizophrenia Schizophrenia and Related Disorders | Recruiting | Icahn School of Medicine at Mount Sinai | 650 | 2024-01-09 | 2026-02-19 | |
| Exercise Therapy in Mental Disorders-study High intensity training (HIT) - Schizophrenia and Related Disorders, Bipolar Disorder | Not applicable | Recruiting | Haukeland University Hospital | 50 | 2023-09-27 | 2025-12-30 |
| Accelerated rTMS for Psychomotor Slowing cTBS (continuous Theta Burst Stimulation) - Schizophrenia; Psychosis, Schizophrenia and Related Disorders | Not applicable | Terminated | University of Bern | 25 | 2023-09-22 | 2024-09-25 |
| Embedded Narrative in Interactive Game Design for Improving Medication Adherence of Schizophrenia Healing Town: Embedded Narrative in Interactive Game (Psycho-education Tool) Design - Schizophrenia and Related Disorders, Medication Adherence | Not applicable | Completed | Zhu Dian | 20 | 2023-09-01 | 2026-04-30 |
| Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Experiences of Hearing Voices Avatar therapy, Cognitive behavioural therapy (CBT) - Auditory Hallucination, Psychotic Disorders | Not applicable | Recruiting | Swinburne University of Technology | 212 | 2023-08-08 | 2024-11-22 |
| EEG Outcomes From Cognitive Behavioural Therapy for Psychosis Cognitive Behavioural Therapy for Psychosis - Psychotic Disorders, Schizophrenia and Related Disorders | Not applicable | Completed | University of Toronto | 20 | 2023-02-01 | 2025-07-29 |
| Mechanistic Clinical Trial of Individualized tDCS for Hallucinations in Schizophrenia neuroConn DC-Stimulator MR, Soterix MxN HD-tES - Schizophrenia and Related Disorders | Not applicable | Withdrawn | Columbia University | 2022-12-01 | 2022-04-05 |
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Schizophrenia (56) · Psychotic Disorders (21) · Mental Disorders (7) · Bipolar Disorder (6) · Bipolar and Related Disorders (3) · Depressive Disorder, Major (3) · Hallucinations (3) · Motor Activity (3) · Psychomotor Disorders (3) · Delusions (2) · Depressive Disorder (2) · Emotional Regulation (2) · Gestures (2) · Nonverbal Communication (2) · Schizophrenia Spectrum and Other Psychotic Disorders (2)
Schizophrenia Spectrum and Other Psychotic Disorders (54) · Mental Disorders (49) · Behavior (17) · Mood Disorders (9) · Nervous System Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Neurobehavioral Manifestations (8) · Neurologic Manifestations (8) · Signs and Symptoms (8) · Bipolar and Related Disorders (5) · Social Behavior (4) · Behavioral Symptoms (3) · Communication (3) · Depressive Disorder (3) · Perceptual Disorders (3)
Therapeutics (6) · Cognitive Behavioral Therapy (4) · Transcranial Magnetic Stimulation (4) · Aripiprazole (2) · Clozapine (2) · Exercise (2) · Paliperidone Palmitate (2) · (R)-3-hydroxybutyl (R)-3-hydroxybutyrate (1) · Alginates (1) · Bupropion (1) · Case Management (1) · Cognitive Remediation (1) · Escitalopram (1) · Fructose (1) · High-Intensity Interval Training (1)
University of Bern (5) · Columbia University (4) · The University of Hong Kong (3) · Centre for Addiction and Mental Health (2) · Dr. Inge Winter (2) · Haukeland University Hospital (2) · Icahn School of Medicine at Mount Sinai (2) · The University of Texas Health Science Center, Houston (2) · University of Toronto (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Beth Israel Deaconess Medical Center (1) · Chia-Hui Hung (1) · Christina Andreou (1) · Edinburgh Napier University (1) · Fraser Health (1)
United States (15) · Switzerland (7) · Canada (5) · Spain (4) · United Kingdom (4) · Germany (3) · Hong Kong (3) · Italy (3) · Netherlands (2) · Norway (2) · Taiwan (2) · Australia (1) · Austria (1) · China (1) · Denmark (1)
Sebastian Walther, MD (4) · Michael Avissar, MD, PhD (2) · Xiaoming Du, PhD (2) · Abraham Reichenberg (1) · Albert KK Chung (1) · Armando J. Rotondi, PhD (1) · Benedicto Crespo Facorro, Professor (1) · Caponnetto Pasquale, PhD (1) · Chia-Hao Ma, MD (1) · Christina Andreou, PD Dr. (1) · David Erickson, PhD (1) · David Kimhy, PhD (1) · Dennis Chak Fai Ma, PhD (1) · Dost Ongur, MD, PhD (1) · Dr Caroline Lawlor (1)
PMID 10689661, PMID 24375458, PMID 28057610, PMID 30157009, PMID 32513294, PMID 33087170, PMID 34615565, PMID 36034912, PMID 36050663, PMID 36510155, PMID 36652687, PMID 36803444, PMID 37422659, PMID 37476005, PMID 38416468, PMID 39488677, PMID 40568354, PMID 40614350, PMID 40804323, PMID 40979217, PMID 41401709, PMID 41808086, PMID 42037481, PMID 42656845
2017 (2), K23MH119318 (2), 2018 (1), 2023 (1), R01MH110623 (1), R01MH117191 (1), R01MH128971 (1), R61MH128390 (1)