11 completed, 4 not yet recruiting, 2 active not recruiting, 2 unknown. 8 Not applicable, 6 Phase 4, 3 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow this drug Literature Review of Alginates trials Research Report on Alginates
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Functional Foods for Health Sodium alginate, Placebo (maltodextrin) - Stress, Psychological | Not applicable | Not yet recruiting | University of Reading | 40 | 2026-10-19 | 2026-10-21 |
| Comparative Effectiveness of Alginate, Magaldrate, Sucralfate, Proton Pump Inhibitors, and Diet in Laryngopharyngeal Reflux Disease Alginate, Magaldrate, Sucralfate - Laryngopharyngeal Reflux Disease | Phase 4 | Not yet recruiting | University of Mons | 800 | 2026-05-01 | 2026-05-28 |
| Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers To determine the efficacy of a gel containing polyhexanide and biguanide, alone or in combination with alginate with or without silver, in preventing biofilm in PU, in terms of healing at 4 weeks - Pressure Ulcers, Pressure Ulcers Stage III | Early Phase 1 | Not yet recruiting | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | 140 | 2026-01-30 | 2026-02-10 |
| Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study Alginate mixed with distilled water, 0.2% Chlorhexidine + Alginate, 1% Chitosan + Alginate - Dimensional Changes | Not applicable | Not yet recruiting | Altamash Institute of Dental Medicine | 96 | 2025-04-01 | 2025-03-28 |
| Alginate vs Sucralfate for GERD Symptomatic Relief Alginate, Sucralfate - GERD | Phase 2 / Phase 3 | Completed | CMH Lahore Medical College and Institute of Dentistry | 140 | 2025-04-01 | 2026-07-15 |
| Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS (R)-3-hydroxybutyl (R)-3-hydroxybutyrate), Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride - Schizophrenia and Related Disorders, Psychosis | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 28 | 2024-12-01 | 2026-04-27 |
| Prevention of Oral Mucositis and Improvement of Quality of Life for Patients With Breast Cancer Undergoing Adjuvant Radiotherapy Alginos Oral Suspension - Breast Carcinoma | Phase 2 | Enrolling by invitation | Taipei City Hospital | 90 | 2024-02-15 | 2025-05-06 |
| Exploratory Pilot Study to Evaluate the Pharmacokinetic Profile of Magaldrate Sodium alginate + sodium bicarbonate + magaldrate + simeticone - Healthy | Phase 4 | Completed | Tecnoquimicas | 10 | 2023-10-31 | 2024-04-16 |
| HONEY for the Treatment of POst-Tonsillectomy Pain Manuka honey MGO 1000, Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring - Post Surgical Pain, Analgesia | Not applicable | Recruiting | East and North Hertfordshire NHS Trust | 100 | 2023-09-04 | 2026-07-07 |
| Primary carE PPi dEprescRibing Trial de-prescription of PPI via intermittent scheme, de-prescription of PPI via on-demand scheme, Alginate - Heartburn, Dyspepsia | Phase 4 | Active not recruiting | Universitaire Ziekenhuizen KU Leuven | 724 | 2023-05-12 | 2025-01-31 |
| Intestinal Ketone Bodies Interfere With the Glycemic Control Alginate, Pea-protein - Healthy Adult Volunteers | Not applicable | Completed | Göteborg University | 8 | 2021-12-05 | 2022-09-30 |
| The Effect of Alginate Supplementation on Weight Management Alginate, Placebo - Overweight and Obesity | Not applicable | Unknown | Newcastle University | 190 | 2020-10-19 | 2023-06-01 |
| A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot Medaxis Debritom+, Sharp Surgical Debridement, Additional Outer Dressing Application - Diabetic Foot Ulcer, Diabetic Foot | Not applicable | Active not recruiting | Medaxis, LLC | 222 | 2020-09-11 | 2024-11-21 |
| The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus Alginates - Barretts Esophagus With Dysplasia | Phase 2 | Completed | Medical University of South Carolina | 24 | 2017-08-25 | 2023-03-08 |
| A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment Alginate, Sucralfate, Hydrotalcite - Dyspepsia | Phase 4 | Completed | Pamukkale University | 300 | 2017-06-20 | 2018-08-31 |
| The Effect of Lamina-G on Gastrointestinal Symptom After Gastric Biopsy Sodium alginate - Gastrointestinal Symptom | Phase 4 | Completed | Kyungpook National University Hospital | 210 | 2017-03-27 | 2020-04-24 |
| Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances sodium alginate, esomeprazole - Gastroesophageal Reflux Disease, Heartburn | Phase 4 | Unknown | Chang Gung Memorial Hospital | 340 | 2014-11-01 | 2014-11-19 |
| Efficacy and Safety of Alginos Oral Suspension to Treat Laryngopharyngeal Reflux Sodium alginate, Placebo - Laryngopharyngeal Reflux | Phase 3 | Completed | TTY Biopharm | 80 | 2011-10-01 | 2015-06-08 |
| Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease Sodium alginate, Omeprazole - Gastroesophageal Reflux Disease, Heartburn | Phase 3 | Completed | Chang Gung Memorial Hospital | 195 | 2010-10-01 | 2012-02-10 |
| The Effect of Different Types of Dietary Fiber on Satiation cellulose, alginate, guar gum - Healthy | Not applicable | Completed | Wageningen University | 123 | 2009-05-01 | 2010-05-11 |
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Gastroesophageal Reflux (5) · Heartburn (3) · Dyspepsia (2) · Obesity (2) · Overweight (2) · Agnosia (1) · Bipolar and Related Disorders (1) · Body Weight (1) · Breast Neoplasms (1) · Diabetic Foot (1) · Emergencies (1) · Esophagitis (1) · Feeding Behavior (1) · Inflammation (1) · Laryngopharyngeal Reflux (1)
Chang Gung Memorial Hospital (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Altamash Institute of Dental Medicine (1) · CMH Lahore Medical College and Institute of Dentistry (1) · East and North Hertfordshire NHS Trust (1) · Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (1) · Göteborg University (1) · Kyungpook National University Hospital (1) · Medaxis, LLC (1) · Medical University of South Carolina (1) · Newcastle University (1) · Pamukkale University (1) · TTY Biopharm (1) · Taipei City Hospital (1) · Tecnoquimicas (1)
Taiwan (4) · United Kingdom (3) · Belgium (2) · Netherlands (2) · United States (2) · Brazil (1) · Denmark (1) · Pakistan (1) · South Korea (1) · Sweden (1) · Turkey (Türkiye) (1)
Arne Astrup, Dr. Med (1) · Cheng-Tang Chiu, M.D. (1) · Cheng-Tang Chiu, MD (1) · David Armstrong, DPM, MD, PhD (1) · Edith Feskens, Dr (1) · George Mochloulis, MD (1) · Gulgun Battal, MD (1) · Karin Huizer, MD/PhD (1) · Muhammad Hafeez, MBBS (1) · Phillip Smith, PhD (1) · Robert Galiano, MD (1) · Tzu-Yu Hsiao, Ph.D. (1) · Yi-Sheng Chou, M.D (1)
PMID 21779093, PMID 22850326, PMID 24024757, PMID 39249590, PMID 40568354, PMID 41997699