6 completed, 1 recruiting, 1 terminated, 1 unknown. 10 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 6, Recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
Follow Sarcoma, Soft Tissue: new trials by email Literature Review of Sarcoma, Soft Tissue trials Research Report on Sarcoma, Soft Tissue
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma DPPG2-TSL-DOX, Dexrazoxane - Sarcoma, Soft Tissue | Phase 1 | Completed | Thermosome GmbH | 8 | 2023-04-19 | 2025-07-28 |
| Olaratumab Plus Trabectedin in Advanced Soft-tissue Sarcoma Patients Soft-tissue Sarcoma Patients Olaratumab and Trabectedin - Sarcoma, Soft Tissue | Phase 1 | Unknown | Grupo Espanol de Investigacion en Sarcomas | 28 | 2018-09-21 | 2023-03-27 |
| Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery BLZ-100 - Sarcoma, Soft Tissue | Phase 1 | Withdrawn | Blaze Bioscience Inc. | 2015-09-01 | 2016-05-26 | |
| A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma Olaratumab, Doxorubicin - Sarcoma, Soft Tissue | Phase 1 | Completed | Eli Lilly and Company | 49 | 2015-01-22 | 2019-11-21 |
| Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients Trabectedin, Radiotherapy - Liposarcoma, Myxoid, Sarcoma, Soft Tissue | Phase 1 / Phase 2 | Recruiting | Grupo Espanol de Investigacion en Sarcomas | 199 | 2014-11-01 | 2023-05-31 |
| Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors nab-paclitaxel - Neuroblastoma, Rhabdomyosarcoma | Phase 1 / Phase 2 | Completed | Celgene | 107 | 2013-12-04 | 2019-12-27 |
| Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia Eltrombopag - Sarcoma, Soft Tissue, Osteosarcoma | Phase 1 | Terminated | Duke University | 1 | 2012-04-01 | 2014-04-02 |
| A Study of Olaratumab in Soft Tissue Sarcoma Olaratumab, doxorubicin - Sarcoma, Soft Tissue | Phase 1 / Phase 2 | Completed | Eli Lilly and Company | 148 | 2010-10-01 | 2017-04-14 |
| TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients combination of TLC D-99 and Ifosfamide - Sarcoma, Soft Tissue | Phase 1 / Phase 2 | Completed | Istituto Clinico Humanitas | 36 | 2006-09-01 | 2009-12-18 |
| Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors Everolimus - Tumors, Brain Tumors | Phase 1 | Completed | St. Jude Children's Research Hospital | 41 | 2004-10-01 | 2015-03-04 |
Sarcoma (10) · Neoplasms (2) · Osteosarcoma (2) · Rhabdomyosarcoma (2) · Bone Neoplasms (1) · Brain Neoplasms (1) · Dermatofibrosarcoma (1) · Fibrosarcoma (1) · Histiocytoma (1) · Leiomyosarcoma (1) · Liposarcoma (1) · Liposarcoma, Myxoid (1) · Melanoma (1) · Neoplasms, Connective and Soft Tissue (1) · Neuroblastoma (1)
Neoplasms by Histologic Type (10) · Neoplasms, Connective and Soft Tissue (9) · Neoplasms (8) · Neoplasms by Site (3) · Neoplasms, Muscle Tissue (3) · Myosarcoma (2) · Neoplasms, Bone Tissue (2) · Neoplasms, Connective Tissue (2) · Bone Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Disease Attributes (1) · Musculoskeletal Diseases (1) · Neoplasms, Adipose Tissue (1)
Doxorubicin (3) · olaratumab (3) · Trabectedin (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Dexrazoxane (1) · Everolimus (1) · Ifosfamide (1) · Radiotherapy (1) · eltrombopag (1) · tozuleristide (1)
Eli Lilly and Company (2) · Grupo Espanol de Investigacion en Sarcomas (2) · Blaze Bioscience Inc. (1) · Celgene (1) · Duke University (1) · Istituto Clinico Humanitas (1) · St. Jude Children's Research Hospital (1) · Thermosome GmbH (1)
United States (6) · Italy (3) · Spain (3) · France (2) · Canada (1) · Germany (1) · Switzerland (1) · United Kingdom (1)
Armando Santoro, MD (1) · Charles Forscher, MD (1) · Ileana Elias, M.D. (1) · Peter Reichardt, PD Dr. (1) · Richard F Riedel, MD (1) · Wayne L Furman, MD (1)
PMID 27291997, PMID 31143880, PMID 31401903, PMID 32077895, PMID 32554315, PMID 32827353
2017 (1), 2023 (1), 261201400046C-0-0-1 (1)