91 completed, 34 unknown, 12 recruiting, 12 terminated. 70 Not applicable, 15 Phase 2, 15 Phase 4, 12 Phase 3, 6 Phase 1.
Follow this condition Literature Review of Retinal Detachment trials Research Report on Retinal Detachment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OCT Macula Biomarkers Before Silicone Oil Removal and Visual Outcome After Silicone Oil Removal Retinal Detachment, Macular Edema | Not yet recruiting | Assiut University | 30 | 2026-11-01 | 2026-10-08 | |
| Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD) Intravitreal 100% C3F8 Injection, Pars plana vitrectomy or pars plana vitrectomy with scleral buckle - Retinal Detachment Rhegmatogenous | Phase 2 / Phase 3 | Not yet recruiting | Wills Eye | 190 | 2026-09-21 | 2026-10-02 |
| Artificial Intelligence-Assisted Lesion-Based Urgent Referral Triage of Ultra-Widefield Retinal Images AI-Assisted UWF Lesion-Based Triage System, Unassisted Interpretation - Vision-Threatening Retinal Lesions, Urgent Referral Retinal Findings | Not applicable | Completed | Xiamen Ophthalmology Center Affiliated to Xiamen University | 11 | 2026-07-01 | 2026-09-22 |
| Reliability of Optical and Ultrasound Biometry in Silicon Filled Eyes optical and ulrtasound biometry - Retinal Detachment | Recruiting | Sohag University | 100 | 2026-05-30 | 2026-07-28 | |
| Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment air, Gas SF6 (Sulfur Hexafluoride) and others - Retinal Detachment Rhegmatogenous | Not applicable | Not yet recruiting | Liverpool University Hospitals NHS Foundation Trust | 150 | 2026-03-20 | 2025-12-24 |
| Surgical Procedure Efficiency Evaluation stuDy UNITY VCS, CONSTELLATION - Cataract, Vitreous Hemorrhage | Recruiting | Alcon Research | 180 | 2026-02-09 | 2026-08-13 | |
| Animated Video Education for Retinal Surgery Patient Education Video Intervention - Retinal Detachment | Not applicable | Not yet recruiting | University of Toronto | 600 | 2026-01-01 | 2025-09-19 |
| 1ry Versus 2ry ILM Peeling in RD Primary ILM peeling, Secondary ILM peeling - Retinal Detachment Rhegmatogenous, ILM Peeling | Not applicable | Recruiting | Sohag University | 100 | 2025-12-15 | 2026-01-16 |
| Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS) Prophylactic (non-invasive) Laser Retinopexy - Stickler Syndrome Type 1, Stickler Syndrome Type 2 | Not applicable | Recruiting | Helen Keller Eye Research Foundation | 500 | 2025-10-30 | 2026-07-01 |
| Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment Perflurocarbon liquid, Without Perflurocarbon liquid - Retinal Displacement After Retinal Detachment Surgery | Not applicable | Recruiting | Norfolk and Norwich University Hospitals NHS Foundation Trust | 292 | 2025-10-28 | 2026-04-14 |
| Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment Nicotinamide Riboside, Placebo, Vitrectomy and Gas tamponade - Retinal Detachment | Phase 4 | Recruiting | Center for Eye Research Australia | 144 | 2025-09-19 | 2026-03-23 |
| Influence of Tamponade on Retinal Shift in Eyes Undergoing Vitrectomy for Rhegmatogenous Retinal Detachment: A Comparison of Gas Versus Silicone Oil in a Pakistani Population Pars plana vitrectomy - Retinal Detachment Rhegmatogenous, Vitrectomy | Not applicable | Completed | Wardah | 78 | 2025-04-15 | 2026-03-31 |
| Head Position Monitoring After Pars Planar Vitrectomy gyroscope embedded eye-sheild - Retinal Detachment, Macular Hole | Active not recruiting | Seoul National University Hospital | 100 | 2024-11-28 | 2025-05-22 | |
| Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery Ursolvan, Placebo - Retinal Detachment | Phase 3 | Recruiting | Hopital Foch | 120 | 2024-08-20 | 2025-05-14 |
| Methotrexate in Retinal Detachment With Proliferative Vitreoretinopathy parsplana vitrectomy, adjunctive use of Methotrexate - Retinal Detachment | Not applicable | Completed | Benha University | 20 | 2024-06-09 | 2025-07-10 |
| Caffeine and Cataract After Pars Plana Vitrectomy Pars plana vitrectomy - Cataract | Not applicable | Unknown | Vienna Institute for Research in Ocular Surgery | 74 | 2024-04-01 | 2024-04-12 |
| "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy" Methotrexate - Proliferative Vitreoretinopathy | Phase 1 / Phase 2 | Unknown | University of Health Sciences Lahore | 120 | 2024-03-01 | 2024-03-01 |
| Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments Retinal Detachment Surgery - Retinal Detachment | Unknown | Central Hospital, Nancy, France | 25 | 2024-03-01 | 2024-03-05 | |
| Lamivudine and Plasma Markers of Inflammation in Retinal Detachment Lamivudine 300 MG, Placebo - Retinal Detachment, Rhegmatogenous Retinal Detachment | Early Phase 1 | Terminated | University of Wisconsin, Madison | 2 | 2024-01-30 | 2024-09-19 |
| Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment Biological Sample Collection - Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR) | Not applicable | Recruiting | Fondazione G.B. Bietti, IRCCS | 260 | 2024-01-24 | 2026-06-02 |
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Retinal Perforations (28) · Vitreoretinopathy, Proliferative (19) · Epiretinal Membrane (17) · Macular Degeneration (15) · Diabetic Retinopathy (11) · Vitreous Hemorrhage (10) · Cataract (6) · Glaucoma (5) · Macular Edema (5) · Vision Disorders (5) · Retinal Degeneration (4) · Retinal Diseases (4) · Choroidal Neovascularization (3) · Diabetes Mellitus (3)
Eye Diseases (161) · Retinal Diseases (158) · Pathological Conditions, Signs and Symptoms (30) · Pathologic Processes (20) · Retinal Degeneration (17) · Nervous System Diseases (15) · Cardiovascular Diseases (14) · Endocrine System Diseases (14) · Vascular Diseases (14) · Signs and Symptoms (12) · Diabetes Complications (11) · Diabetes Mellitus (11) · Diabetic Angiopathies (11) · Neurologic Manifestations (11) · Eye Hemorrhage (10)
Vitrectomy (12) · Ranibizumab (8) · Scleral Buckling (5) · Bevacizumab (4) · Lasers (4) · aflibercept (4) · Intravitreal Injections (3) · Triamcinolone Acetonide (3) · perflutren (3) · Air (2) · Cryotherapy (2) · Ophthalmic Solutions (2) · Predictive Value of Tests (2) · Propofol (2) · Sulfur Hexafluoride (2)
Benha University (5) · Unity Health Toronto (5) · Central Hospital, Nancy, France (4) · Minia University (4) · Wills Eye (4) · Centre Hospitalier Universitaire Dijon (3) · National Taiwan University Hospital (3) · Shahid Beheshti University of Medical Sciences (3) · Sohag University (3) · Sun Yat-sen University (3) · Asociación para Evitar la Ceguera en México (2) · Assistance Publique - Hôpitaux de Paris (2) · Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (2) · Dar El Oyoun Hospital (2) · GuangZhou WeiShiBo Biotechnology Co., ltd (2)
United States (29) · Egypt (18) · France (15) · Canada (10) · China (10) · Iran (4) · Israel (4) · Italy (4) · United Kingdom (4) · Australia (3) · Austria (3) · Brazil (3) · Mexico (3) · South Korea (3) · Switzerland (3)
Jason Hsu, MD (5) · Ahmed A Abdelshafy, MD (2) · Amy Schaberg, BSN (2) · Anne Fung, MD (2) · Hamid Ahmadieh, MD (2) · Hugo Quiroz-Mercado, MD (2) · Justis P Ehlers, MD (2) · Michael Altaweel, MD (2) · Qianying Gao, MD,Ph.D (2) · Rajeev Muni, FRSCS (2) · Abdul Sami Memon, FCPS (1) · Adiel Barak, Prof (1) · Ahmad Z Jamil, FCPS,FRCS (1)
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K23EY022947 (1), U01EY028079 (1)