2 enrolling by invitation, 2 recruiting, 1 not yet recruiting, 1 unknown. 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Enrolling by invitation 2 |
Follow PSP - Progressive Supranuclear Palsy: new trials by email Literature Review of PSP - Progressive Supranuclear Palsy trials Research Report on PSP - Progressive Supranuclear Palsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Evaluating the Effect of Transcranial Direct Current Stimulation (tDCS) Targeting the Right Inferior Frontal Gyrus on Inhibitory Control in Patients With PSP tDCS, or transcranial direct current stimulation - PSP - Progressive Supranuclear Palsy | Not applicable | Not yet recruiting | Nantes University Hospital | 20 | 2026-09-15 | 2026-09-14 |
| The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31 LM11A-31, Matching Placebo - PSP - Progressive Supranuclear Palsy | Phase 2 | Enrolling by invitation | Adam Boxer | 147 | 2026-07-29 | 2026-08-12 |
| The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1 AADvac1, Matching Placebo - PSP - Progressive Supranuclear Palsy | Phase 2 | Enrolling by invitation | Adam Boxer | 146 | 2026-07-29 | 2026-08-13 |
| Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders UHR PET/CT scan of the brain with ¹⁸F-FDG, UHR PET/CT scan of the brain with ¹⁸F-PE2I, UHR PET/CT scan of the brain with ¹⁸F-SynVesT-1 - Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 300 | 2026-02-13 | 2026-04-03 |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear Palsy Pupillometry - PSP - Progressive Supranuclear Palsy, PD - Parkinson's Disease | Unknown | Massachusetts General Hospital | 56 | 2017-11-01 | 2017-11-07 |
Supranuclear Palsy, Progressive (6) · Alzheimer Disease (2) · Amyotrophic Lateral Sclerosis (2) · Frontotemporal Dementia (2) · Multiple System Atrophy (2) · Parkinson Disease (2) · Shy-Drager Syndrome (2) · Corticobasal Degeneration (1) · Dementia (1) · Lewy Body Disease (1) · Multiple system atrophy (MSA) with orthostatic hypotension (1) · Psychotic Disorders (1) · REM Sleep Behavior Disorder (1) · Schizophrenia (1)
Basal Ganglia Diseases (6) · Brain Diseases (6) · Central Nervous System Diseases (6) · Cranial Nerve Diseases (6) · Eye Diseases (6) · Movement Disorders (6) · Nervous System Diseases (6) · Neurodegenerative Diseases (6) · Neurologic Manifestations (6) · Ocular Motility Disorders (6) · Ophthalmoplegia (6) · Paralysis (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Tauopathies (6)
AADvac1 (1) · LM11A-31 (1) · Transcranial Direct Current Stimulation (1)
Adam Boxer (2) · Massachusetts General Hospital (2) · Nantes University Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1)
United States (4) · Belgium (1) · France (1)
Adam Boxer, MD, PhD (2) · Anne-Marie Wills, MD (2) · Irene Litvan, MD (2) · Julio Rojas-Martinez, MD, PhD (2) · Shirley H Wray, MD, PhD (1)
R01AG085029 (2)