14 completed. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 14 |
Follow Primary Dysautonomias: new trials by email Literature Review of Primary Dysautonomias trials Research Report on Primary Dysautonomias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of Parkinson's And Zoledronic Acid Zoledronic Acid 5Mg/Bag 100Ml Inj, Placebo - Parkinson Disease, Osteoporosis | Phase 4 | Completed | California Pacific Medical Center Research Institute | 2721 | 2019-11-15 | 2026-06-25 |
| Lundbeck TOMs Orthostatic Hypotension Droxidopa 100 MG [Northera] - Orthostatic Hypotension, Idiopathic Parkinson Disease | Phase 4 | Completed | Alberto Espay, MD, MSc | 9 | 2019-02-11 | 2022-09-26 |
| Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury Northera, Placebo - Hypotension, Orthostatic, Hypotension | Phase 4 | Completed | James J. Peters Veterans Affairs Medical Center | 22 | 2018-06-01 | 2025-03-07 |
| Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OH Midodrine, Atomoxetine - Neurogenic Orthostatic Hypotension | Phase 4 | Completed | Seoul National University Hospital | 50 | 2018-01-01 | 2019-04-05 |
| Dawn Simulation and Postural Hypotension Light - Orthostatic Hypotension | Phase 4 | Completed | VA Palo Alto Health Care System | 35 | 2016-09-01 | 2019-10-25 |
| Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension Droxidopa capsules, Placebo capsules - Symptomatic Neurogenic Orthostatic Hypotension | Phase 4 | Completed | H. Lundbeck A/S | 453 | 2016-02-11 | 2023-08-23 |
| Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) Propranolol, Bisoprolol, Propranolol+pyridostigmine - Postural Orthostatic Tachycardia Syndrome | Phase 4 | Completed | Seoul National University Hospital | 150 | 2014-03-01 | 2018-04-18 |
| Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension Midodrine HCl, Placebo - Orthostatic Hypotension | Phase 4 | Completed | Shire | 24 | 2012-05-14 | 2021-06-08 |
| Optimal Balloon Catheter Placement During Sonohysterography sonohysterography with inflated catheter in uterine cavity, sonohysterography with inflated catheter in cervical cavity - Infertility | Phase 4 | Completed | Royan Institute | 300 | 2012-05-01 | 2014-05-06 |
| Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises strengthening exercise, flexibility exercise - Fibromyalgia | Phase 4 | Completed | Federal University of Espirito Santo | 66 | 2010-07-01 | 2013-12-09 |
| Clinical Trial for the Prevention of Vasovagal Syncope fludrocortisone acetate - Syncope, Vasovagal, Neurally-Mediated | Phase 4 | Completed | University of Calgary | 213 | 2005-05-01 | 2019-10-15 |
| Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension Midodrine hydrochloride, Placebo - Hypotension, Orthostatic | Phase 4 | Completed | Shire | 24 | 2004-09-08 | 2021-06-14 |
| Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Propranolol - Neurocardiogenic Syncope | Phase 4 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2003-05-01 | 2008-03-04 |
| A Study for Patients With Neurogenic Orthostatic Hypotension Midodrine Hydrochloride - Hypotension, Orthostatic | Phase 4 | Completed | Shire | 140 | 1997-12-01 | 2021-06-11 |
Hypotension, Orthostatic (7) · Parkinson Disease (3) · Syncope, Vasovagal (3) · Multiple System Atrophy (2) · Autonomic Nervous System Diseases (1) · Fibromyalgia (1) · Fractures, Bone (1) · Hypotension (1) · Infertility (1) · Lewy Body Disease (1) · Motor Activity (1) · Orthostatic Intolerance (1) · Osteoporosis (1) · Parkinsonian Disorders (1) · Postural Orthostatic Tachycardia Syndrome (1)
Nervous System Diseases (14) · Autonomic Nervous System Diseases (13) · Orthostatic Intolerance (10) · Cardiovascular Diseases (7) · Vascular Diseases (7) · Hypotension (6) · Central Nervous System Diseases (4) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Basal Ganglia Diseases (3) · Brain Diseases (3) · Consciousness Disorders (3) · Movement Disorders (3)
Midodrine (4) · Droxidopa (3) · Propranolol (2) · Atomoxetine Hydrochloride (1) · Bisoprolol (1) · Ultraviolet Therapy (1) · Zoledronic Acid (1) · fludrocortisone acetate (1)
Shire (3) · Seoul National University Hospital (2) · Alberto Espay, MD, MSc (1) · California Pacific Medical Center Research Institute (1) · Federal University of Espirito Santo (1) · H. Lundbeck A/S (1) · James J. Peters Veterans Affairs Medical Center (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Royan Institute (1) · University of Calgary (1) · VA Palo Alto Health Care System (1)
United States (10) · South Korea (2) · Brazil (1) · Canada (1) · Iran (1)
Chu Kon (1) · Fatemeh Zafarani, MSc (1) · Firoozeh Ahmadi, MD (1) · Hamid Gourabi, PhD (1) · Jill M Wecht, Ed.D (1) · Kon Chu, MD, PhD (1) · Maria Bernadete RO Gavi, Master (1) · Robert S. Sheldon, MD PhD (1) · Steve Cummings, MD (1)
PMID 16781217, PMID 24651512, PMID 27364043, PMID 27372462, PMID 29500811, PMID 29766871, PMID 32307533, PMID 33649343, PMID 35107750
R01AG059417 (1)