229 completed, 103 unknown, 48 recruiting, 22 active not recruiting. 206 Not applicable, 40 Phase 3, 27 Phase 4, 23 Phase 2, 7 Phase 1.
Follow Preterm Birth: new trials by email Literature Review of Preterm Birth trials Research Report on Preterm Birth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| NICU-to-Home Dyadic Support for Very Preterm Infants and Families Homebased SPEEDI, Telehealth SPEEDI - Preterm Birth, Very Preterm Infant | Not applicable | Not yet recruiting | University of Minnesota | 40 | 2026-11-16 | 2026-10-09 |
| Initial Oxygen Concentration at Birth in Late-Preterm Infants 60% Oxygen Group - Infants will start in 60% oxygen, 30% Oxygen Group - Infants will start in 30% oxygen - Preterm Birth | Not applicable | Not yet recruiting | University of Alberta | 1520 | 2026-11-01 | 2026-09-10 |
| Cervical Stiffness in Women With Threatened Preterm Labor Pregnolia System - Preterm Labor, Preterm Birth | Recruiting | Pregnolia AG | 100 | 2026-10-15 | 2026-10-21 | |
| Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities Care coordination, Electronic massage, support gift #1 - Preterm Birth Complication, Preterm Birth | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1228 | 2026-10-01 | 2026-09-29 |
| Music Intervention for Preterm Birth Music Intervention (MI), Sham Control (SC) - Preterm Birth | Not applicable | Recruiting | Columbia University | 142 | 2026-09-29 | 2026-10-19 |
| Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth Handstimulation of breast - Preterm Birth, PPROM | Not applicable | Not yet recruiting | Odense University Hospital | 250 | 2026-09-01 | 2025-09-24 |
| The Effect of Web-Based Counselling on Breastfeeding Experiences and Infant Care Competence Among Mothers of Preterm Babies Web-Based Breastfeeding Counseling and Infant Care Program, control group - Preterm Birth | Not applicable | Not yet recruiting | Medipol University | 56 | 2026-09-01 | 2026-07-21 |
| Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS) Educational Intervention - Environmental Exposure, Pregnancy Related | Not applicable | Recruiting | The University of Texas Medical Branch, Galveston | 300 | 2026-08-27 | 2026-09-14 |
| Maternal Periodontal Inflammation and Pregnancy Outcomes: Salivary and Amniotic Biomarkers Periodontal Disease, Pregnancy | Not yet recruiting | Saglik Bilimleri Universitesi | 80 | 2026-08-20 | 2026-07-29 | |
| Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants Nicotinamide Riboside (NR), Placebo - Preterm Birth, Inadequate Milk Production | Phase 2 / Phase 3 | Recruiting | University of California, Davis | 40 | 2026-08-19 | 2026-09-14 |
| The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health 'Standard of Care PLUS' - Preterm Birth, Preeclampsia | Not applicable | Not yet recruiting | GrowBaby Life Project | 500 | 2026-08-01 | 2026-04-30 |
| DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention Multicomponent deimplementation strategy - Preterm Birth, Activity Restriction | Not applicable | Recruiting | University of Pennsylvania | 237 | 2026-07-16 | 2026-08-10 |
| Healthy Expectancy Through Routine Antenatal STI Screening Chlamydia trachomatis and Neisseria gonorrhoeae screening - Antenatal Health, Antenatal Care | Not applicable | Recruiting | Adriane Wynn | 2000 | 2026-05-25 | 2026-07-02 |
| Bed Rest With a Short Cervix on Preterm Birth Activity Restriction, No Activity Restriction - Preterm Birth, Cervical Insufficiency | Not applicable | Not yet recruiting | Julie Glavind | 6000 | 2026-05-01 | 2026-05-11 |
| Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support Caffeine, Placebo - Preterm Birth, Caffeine | Phase 2 | Not yet recruiting | Queen's University | 62 | 2026-04-01 | 2026-03-10 |
| Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial Xylitol Chewing gum, Sorbitol chewing gum - Preterm Birth, Low Birthweight Neonate | Phase 2 / Phase 3 | Recruiting | University of Washington | 6000 | 2026-03-26 | 2026-09-10 |
| The Impact of Image Acquisition in Cervical Ultrasound on AI-Based Prediction of Preterm Birth in Clinical Practice Cervical ultrasound image acquisition - Preterm Birth, Artificial Intelligence (AI) in Diagnosis | Recruiting | Copenhagen University Hospital, Rigshospitalet | 2000 | 2026-03-11 | 2026-05-20 | |
| Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth Preterm birth risk scoring system, Transvaginal ultrasound cervical length measurement, Vaginal Progesterone - Preterm Birth | Not applicable | Not yet recruiting | Ningbo University | 1000 | 2026-03-01 | 2026-02-17 |
| Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates Lung monitoring with the Neola device - RDS of Prematurity, Preterm Birth | Not applicable | Not yet recruiting | Neola Medical Inc | 22 | 2026-03-01 | 2025-07-11 |
Showing 20 of 460. Sign in to see all of them.
Premature Birth (460) · Obstetric Labor, Premature (43) · Pregnancy Complications (25) · Pre-Eclampsia (23) · Fetal Growth Retardation (14) · Diabetes, Gestational (13) · Birth Weight (12) · Preterm Premature Rupture of the Membranes (12) · Uterine Cervical Incompetence (12) · Bronchopulmonary Dysplasia (11) · Hypertension, Pregnancy-Induced (11) · Respiratory Distress Syndrome (9) · Stillbirth (8) · Fetal Membranes, Premature Rupture (7) · Pulmonary Atelectasis (7)
Female Urogenital Diseases and Pregnancy Complications (460) · Urogenital Diseases (460) · Obstetric Labor Complications (457) · Pregnancy Complications (435) · Obstetric Labor, Premature (417) · Pathological Conditions, Signs and Symptoms (78) · Pathologic Processes (46) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (45) · Signs and Symptoms (37) · Respiratory Tract Diseases (31) · Behavior (28) · Lung Diseases (26) · Infections (25) · Genital Diseases (24) · Nutritional and Metabolic Diseases (23)
Progesterone (18) · Cerclage, Cervical (10) · Azithromycin (6) · Dexamethasone (5) · Pessaries (5) · Betamethasone (4) · Exercise (4) · Nifedipine (4) · Standard of Care (4) · Utrogestan (4) · 17 alpha-Hydroxyprogesterone Caproate (3) · Amoxicillin (3) · Aspirin (3) · Docosahexaenoic Acids (3) · Music Therapy (3)
Federico II University (14) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (8) · University of Pennsylvania (8) · Johns Hopkins Bloomberg School of Public Health (5) · Thomas Jefferson University (5) · University of Oxford (5) · Children's Hospital of Philadelphia (4) · Columbia University (4) · Gazi University (4) · Maternal-Infantil Vall d´Hebron Hospital (4) · McMaster University (4) · Mỹ Đức Hospital (4) · Selcuk University (4) · University of Minnesota (4) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (3)
United States (134) · Italy (39) · Turkey (Türkiye) (28) · Canada (26) · France (21) · United Kingdom (19) · China (17) · Egypt (15) · Spain (14) · Germany (11) · Israel (11) · Netherlands (10) · Austria (9) · Denmark (9) · India (9)
Roberto Romero, M.D. (7) · Emmanuel Bujold, MD, MSc (4) · Michal A Elovitz, MD (3) · Sarah Keim, PhD (3) · Steve N Caritis, MD (3) · Amanda Roman, MD (2) · Amit Mukerji, MD (2) · Andrew Combs, MD (2) · Annette Conzelmann, Prof. Dr. (2) · Axel Franz, Prof. Dr. (2) · Chiara Tersigni, MD (2) · Dilys Walker, MD (2) · Elena Carreras (2) · Graham G Ashmead, MD (2) · Haijun Wang, Ph.D (2)
PMID 36453699, PMID 32421208, PMID 33368142, PMID 10740336, PMID 11921380, PMID 12796914, PMID 15023372, PMID 16187156, PMID 16410042, PMID 17241817, PMID 17299499, PMID 17334234, PMID 17344252, PMID 17625573, PMID 17666605, PMID 17671253, PMID 17671254, PMID 18281199, PMID 19155896, PMID 19285652, PMID 19664690, PMID 19692803, PMID 19716543, PMID 19757875, PMID 19952869, PMID 20008425, PMID 20093894, PMID 20331587, PMID 20350189, PMID 20576253, PMID 20811016, PMID 20869038, PMID 20925928, PMID 20980489, PMID 21118924, PMID 21173653, PMID 21508745, PMID 21620357, PMID 21683194, PMID 21821542, PMID 21884372, PMID 22168920, PMID 22299027, PMID 22475493, PMID 22693172, PMID 22829919, PMID 22916296, PMID 22992312, PMID 23068310, PMID 23093256
K23HD102560 (2), U10HD021410 (2), U10HD027869 (2), U10HD027915 (2), U10HD027917 (2), U10HD034208 (2), U10HD036801 (2), U10HD040485 (2), U10HD040500 (2), U10HD040512 (2), U10HD040544 (2), U10HD040545 (2), U10HD040560 (2), 2015 (1), 2017 (1)