21 completed, 7 unknown, 5 withdrawn, 4 recruiting. 40 Phase 3, 11 Phase 2.
Follow Preterm Birth: new trials by email Literature Review of Preterm Birth trials Research Report on Preterm Birth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants Nicotinamide Riboside (NR), Placebo - Preterm Birth, Inadequate Milk Production | Phase 2 / Phase 3 | Recruiting | University of California, Davis | 40 | 2026-08-19 | 2026-09-14 |
| Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial Xylitol Chewing gum, Sorbitol chewing gum - Preterm Birth, Low Birthweight Neonate | Phase 2 / Phase 3 | Recruiting | University of Washington | 6000 | 2026-03-26 | 2026-09-10 |
| Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries Oral nitrofurantoin monohydrate/macrocrystals, Placebo - Preterm Birth, Small for Gestational Age (SGA) | Phase 3 | Recruiting | NICHD Global Network for Women's and Children's Health | 1134 | 2025-12-08 | 2026-01-22 |
| Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates Antibiotics - Sepsis, PROM, Preterm (Pregnancy) | Phase 3 | Recruiting | Indian Council of Medical Research | 1500 | 2025-06-07 | 2026-10-27 |
| Skincubator, a Novel Incubator for Skin to Skin Contact Feasibility Study Skincubator 2 - Preterm, Preterm Birth | Phase 2 / Phase 3 | Not yet recruiting | Itamar Nitzan | 50 | 2024-08-31 | 2024-08-09 |
| The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth Prednisone 5Mg - Preterm Birth | Phase 2 / Phase 3 | Completed | University of Mostar | 26 | 2023-11-08 | 2025-02-19 |
| Metformin to Prevent Preterm Birth in Twin Pregnancy Metformin, Placebo oral tablet - Preterm Birth, Premature Obstetric Labor | Phase 2 / Phase 3 | Unknown | The University of Hong Kong | 790 | 2022-06-01 | 2022-06-23 |
| To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis Steroid Drug, Tocolytic Agents - Preterm Birth, Preterm Labor | Phase 3 | Completed | Fundacion Clinic per a la Recerca Biomédica | 247 | 2021-05-05 | 2025-03-12 |
| Surfactant Nebulization for the Early Aeration of the Preterm Lung Surfactant nebulisation - Preterm Birth, Respiratory Distress Syndrome | Phase 3 | Completed | University of Zurich | 32 | 2021-03-19 | 2024-07-08 |
| Single Dose Antenatal Corticosteroids (SNACS) for Women at Risk of Preterm Birth 12 mg betamethasone + placebo, 24 mg betamethasone - Preterm Birth, Complication of Prematurity | Phase 3 | Completed | McMaster University | 30 | 2021-03-01 | 2023-08-23 |
| Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length Micronised vaginal progesterone, Vaginal pessary - Preterm Birth | Phase 3 | Completed | National University of Malaysia | 142 | 2019-10-01 | 2024-01-23 |
| Effect of Early Use of Caffeine Citrate in Preterm Neonates Caffeine Citrate - Preterm Birth | Phase 3 | Completed | Ain Shams University | 54 | 2019-04-05 | 2019-07-02 |
| Progesterone to Prevent Preterm Delivery Dydrogesterone Oral Tablet, Placebo Oral Tablet - Preterm Birth | Phase 2 / Phase 3 | Unknown | The University of Hong Kong | 1714 | 2019-01-15 | 2019-04-10 |
| Transvaginal Ultrasound Cervical Length Screening in Singleton Pregnancy Without Prior Spontaneous Preterm Birth TVU CL screening - Preterm Birth | Phase 3 | Withdrawn | Federico II University | 2018-07-23 | 2018-11-19 | |
| Cerclage for Twins With Short Cervix Cervical Cerclage placement, Vaginal Progesterone - Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2 | Phase 2 / Phase 3 | Withdrawn | Pediatrix | 2017-10-01 | 2018-03-21 | |
| Progesterone and Cervical Pessary in Twins Arabin Pessary, Vaginal Progesterone, Arabin Pessary and Progesterone - Preterm Birth, Twin Pregnancy With Antenatal Problem | Phase 2 / Phase 3 | Unknown | Mario Henrique Burlacchini de Carvalho | 312 | 2017-02-21 | 2017-03-15 |
| Physical Examination-Indicated Pessary Arabin Pessary, Cervical cerclage - PreTerm Birth | Phase 3 | Withdrawn | Federico II University | 2016-11-01 | 2018-11-19 | |
| Cervical Pessary in Women With Arrested Preterm Labor and Short Cervix Arabin cervical pessary - Preterm Birth | Phase 3 | Withdrawn | Federico II University | 2016-07-01 | 2018-11-19 | |
| Assessment of DHA On Reducing Early Preterm Birth Docosahexaenoic acid - 800mg/day, Docosahexaenoic acid - 200mg/day, Placebo - Preterm Birth | Phase 3 | Completed | University of Kansas Medical Center | 1100 | 2016-06-08 | 2021-03-30 |
Showing 20 of 40. Sign in to see all of them.
Premature Birth (40) · Obstetric Labor, Premature (4) · Gingivitis (2) · Periodontal Diseases (2) · Pregnancy Complications (2) · Preterm Premature Rupture of the Membranes (2) · Respiratory Distress Syndrome (2) · Bacteriuria (1) · Fetal Membranes, Premature Rupture (1) · Infant Death (1) · Learning Disabilities (1) · Magnesium Deficiency (1) · Malaria (1) · Malnutrition (1) · Neonatal Sepsis (1)
Female Urogenital Diseases and Pregnancy Complications (40) · Urogenital Diseases (40) · Obstetric Labor Complications (39) · Pregnancy Complications (38) · Obstetric Labor, Premature (36) · Infections (6) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Female Urogenital Diseases (3) · Genital Diseases (3) · Death (2) · Genital Diseases, Female (2) · Gingival Diseases (2) · Lung Diseases (2) · Mouth Diseases (2)
Progesterone (6) · 17 alpha-Hydroxyprogesterone Caproate (3) · Pessaries (3) · Utrogestan (3) · Betamethasone (2) · Cerclage, Cervical (2) · Saline Solution (2) · 17-alpha-Hydroxyprogesterone (1) · Adrenal Cortex Hormones (1) · Anti-Bacterial Agents (1) · Docosahexaenoic Acids (1) · Dydrogesterone (1) · Ethanol (1) · Folic Acid (1) · Iron (1)
Federico II University (6) · The George Washington University Biostatistics Center (3) · Ain Shams University (2) · Johns Hopkins Bloomberg School of Public Health (2) · King's College Hospital NHS Trust (2) · The University of Hong Kong (2) · AMAG Pharmaceuticals, Inc. (1) · Assiut University (1) · Common Sense (1) · Fetal Medicine Foundation (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Hillel Yaffe Medical Center (1) · Indian Council of Medical Research (1) · Instituto Valenciano de Infertilidad, IVI VALENCIA (1) · Itamar Nitzan (1)
United States (9) · Italy (8) · Brazil (4) · Spain (4) · India (3) · Bangladesh (2) · Canada (2) · Chile (2) · Egypt (2) · Malawi (2) · United Kingdom (2) · Australia (1) · Austria (1) · Bosnia and Herzegovina (1) · Bulgaria (1)
Andrew Combs, MD (2) · Bassem El Sayed (1) · Cynthia Gyamfi Bannerman, MD (1) · Daniel Erchick, PhD (1) · David S McKenna, MD (1) · Dwight Rouse, MD (1) · Elizabeth A Thom, Ph.D. (1) · Elizabeth A Thom, PhD (1) · Greg Valentine (1) · Hisham Awad (1) · Itamar Nitzan, M.D (1) · Joao G Alves, PhD (1) · Keith P West, Jr. (1) · Kellie Murphy, MD, MSc, FRCSC (1) · Kenneth M Maleta, MBBS, PhD (1)
PMID 17671253, PMID 17671254, PMID 19155896, PMID 19716543, PMID 20008425, PMID 20093894, PMID 20350189, PMID 20925928, PMID 21118924, PMID 21173653, PMID 21508745, PMID 21620357, PMID 22299027, PMID 22829919, PMID 23198734, PMID 23432801, PMID 23477995, PMID 23635681, PMID 23976885, PMID 24225354, PMID 24853593, PMID 25005784, PMID 25034325, PMID 25425377, PMID 25536256, PMID 25985774, PMID 26186135, PMID 26431336, PMID 26842679, PMID 27604769, PMID 27633433, PMID 27721479, PMID 27769295, PMID 27872823, PMID 27924104, PMID 28193189, PMID 29260226, PMID 29469929, PMID 29599112, PMID 29599478, PMID 29992272, PMID 30455342, PMID 30670451, PMID 30673618, PMID 30797625, PMID 30893310, PMID 31006806, PMID 31035376, PMID 31278280, PMID 31652479
U10HD021410 (2), U10HD027869 (2), U10HD027915 (2), U10HD027917 (2), U10HD034208 (2), U10HD036801 (2), U10HD040485 (2), U10HD040500 (2), U10HD040512 (2), U10HD040544 (2), U10HD040545 (2), U10HD040560 (2), R01HD119029 (1), R01HD119055 (1), U01HL098354 (1)