16 completed, 9 unknown, 4 not yet recruiting, 2 recruiting. 16 Not applicable, 4 Phase 4, 2 Phase 1, 2 Phase 3, 1 Phase 2.
Follow Uterine Cervical Incompetence: new trials by email Literature Review of Uterine Cervical Incompetence trials Research Report on Uterine Cervical Incompetence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities Care coordination, Electronic massage, support gift #1 - Preterm Birth Complication, Preterm Birth | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1228 | 2026-10-01 | 2026-09-29 |
| Azithromycin for Cerclage Prophylaxis Azithromycin Prophylaxis, Azithromycin Placebo, Cefazolin - Cervical Insufficiency | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 80 | 2026-09-01 | 2026-08-27 |
| Bed Rest With a Short Cervix on Preterm Birth Activity Restriction, No Activity Restriction - Preterm Birth, Cervical Insufficiency | Not applicable | Not yet recruiting | Julie Glavind | 6000 | 2026-05-01 | 2026-05-11 |
| Use of Nitrous Oxide for Pain and Anxiety Management During Cervical Cerclage Removal Inhaled nitrous oxide - Preterm Delivery, Cervical Cerclage | Not applicable | Not yet recruiting | Kaplan Medical Center | 60 | 2026-05-01 | 2026-04-08 |
| Long-Term Patient-Reported Maternal Outcomes Following Abdominal Cerclage for the Prevention of Preterm Birth Abdominal cerclage (open or laparoscopic) - Cerclage, Cervical, Cervical Insufficiency | Enrolling by invitation | University of Aarhus | 1200 | 2025-03-05 | 2025-03-13 | |
| Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey - Cervical Insufficiency, Preterm Birth | Not applicable | Recruiting | Henry Ford Health System | 550 | 2025-01-20 | 2026-03-09 |
| Pregnancy Outcomes According to Cervical Cerclage Indications and Factors Affecting Pregnancy Duration and Outcomes transvaginal cervical cerclage by Mc Donald technique - Cervical Incompetence (Complicating Pregnancy) | Completed | Başakşehir Çam & Sakura City Hospital | 129 | 2024-05-10 | 2024-06-05 | |
| Nordic Randomized Trial on Laparoscopic Versus Vaginal Cerclage Laparoscopic cerclage, Vaginal cerclage - Preterm Birth, Cervical Insufficiency | Not applicable | Recruiting | University of Aarhus | 188 | 2024-01-31 | 2024-12-10 |
| Cervical Stiffness Assessment in High-risk Pregnancies for Preterm Birth Cervical Insufficiency, Cervical Stiffness | Completed | Luzerner Kantonsspital | 21 | 2023-07-27 | 2026-05-29 | |
| Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study Hannah Cervical Cup (2 mm Delta), Hannah Cervical Cup (4 mm Delta), Hannah Cervical Cup (6 mm Delta) - Preterm Birth, Cervical Incompetence | Phase 1 | Unknown | Galena Innovations, LLC | 40 | 2023-04-01 | 2022-08-26 |
| Cervical Softening and the Prediction of Preterm Birth Measurement of cervical stiffness by Pregnolia Device - Preterm Birth, Threatened Preterm Labor | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 390 | 2022-08-18 | 2023-09-05 | |
| Cervical Occlusion Double-level Stitch Application Double-level cervical cerclage, Single-level cervical cerclage - Cervical Incompetence | Not applicable | Completed | Centre of Postgraduate Medical Education | 81 | 2022-03-11 | 2025-09-30 |
| Relation of the Area of Cerclage With Preterm Birth Type of cerclage procedure Mc Donald - Cervical Insufficiency | Unknown | Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital | 22 | 2022-01-21 | 2022-03-04 | |
| Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial Azithromycin 1 gram IV, Cefazolin and indomethacin - Preterm Birth, Obstetric Labor, Premature | Phase 4 | Unknown | Thomas Jefferson University | 50 | 2021-12-20 | 2023-06-26 |
| Intramuscular vs Rectal Progesterone in Preventing Preterm Labour After Cervical Cerclage Intramuscular Progesterone, Rectal Progesterone - Preterm Labour, Cervical Insufficiency | Not applicable | Completed | Hina Mukhtar | 820 | 2021-10-26 | 2025-12-29 |
| Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage? Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%) - Cervical Incompetence in Pregnancy as Antepartum Condition | Phase 4 | Completed | Guy's and St Thomas' NHS Foundation Trust | 129 | 2021-08-27 | 2026-06-08 |
| Effectiveness of Cervico-isthmic Cerclage Cervico-isthmic cerclage - Cerclage, Cervical, Cervical Insufficiency | Completed | Hospices Civils de Lyon | 45 | 2021-06-13 | 2022-01-11 | |
| 4 Versus 6 cm Active Phase of Labour oxytocin augmentation - Labor Complication, Cervix; Open | Completed | National University of Malaysia | 155 | 2021-05-01 | 2022-04-29 | |
| Cervical Stiffness Measurement in Cervical Insufficiency Pregnolia - Pregnancy Related, Cervical Insufficiency | Completed | Tufts Medical Center | 136 | 2020-01-15 | 2022-09-21 | |
| Dose Comparison of Misoprostol for Cervix Ripening Before Operative Hysteroscopy. Misoprostol 200mcg Tab, Misoprostol 800mcg Tab - Cervix; Open | Phase 3 | Completed | Professor Fernando Figueira Integral Medicine Institute | 80 | 2019-11-07 | 2020-10-08 |
Showing 20 of 36. Sign in to see all of them.
Premature Birth (19) · Obstetric Labor, Premature (7) · Pregnancy Complications (5) · Obstetric Labor Complications (2) · Abortion, Spontaneous (1) · Depression, Postpartum (1) · Disease (1) · Hypertension, Pregnancy-Induced (1) · Infections (1) · Motor Activity (1) · Patient Participation (1) · Pre-Eclampsia (1) · Preterm Premature Rupture of the Membranes (1) · Stress, Psychological (1)
Abortion, Habitual (36) · Female Urogenital Diseases (36) · Female Urogenital Diseases and Pregnancy Complications (36) · Genital Diseases (36) · Genital Diseases, Female (36) · Urogenital Diseases (36) · Uterine Cervical Diseases (36) · Uterine Diseases (36) · Abortion, Spontaneous (35) · Pregnancy Complications (31) · Obstetric Labor Complications (21) · Obstetric Labor, Premature (15) · Behavior (2) · Behavioral Symptoms (1) · Cardiovascular Diseases (1)
Bupivacaine (3) · Cefazolin (3) · Cerclage, Cervical (2) · Indomethacin (2) · Progesterone (2) · APF protein, Lactobacillus crispatus (1) · Amyloid (1) · Anesthesia, General (1) · Anesthesia, Spinal (1) · Anti-Bacterial Agents (1) · Aspirin (1) · Base Sequence (1) · Bed Rest (1) · Clindamycin (1) · Exercise (1)
University of Aarhus (3) · Tufts Medical Center (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ain Shams University (1) · Başakşehir Çam & Sakura City Hospital (1) · Center For Maternal Fetal Medicine (1) · Centre of Postgraduate Medical Education (1) · Chinese University of Hong Kong (1) · Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital (1) · Galena Innovations, LLC (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hallym University Kangnam Sacred Heart Hospital (1) · Henry Ford Health System (1) · Hina Mukhtar (1) · Hospices Civils de Lyon (1)
United States (12) · Denmark (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Spain (2) · Switzerland (2) · Australia (1) · Brazil (1) · Czechia (1) · Egypt (1) · France (1) · Hong Kong (1) · India (1) · Israel (1) · Malaysia (1)
Andrew Combs, MD (1) · Anna Kajdy, MD PhD (1) · Ashley C Crafton (1) · Can Tekin Iskender, MD (1) · Dan Drzymalski, MD (1) · Desire Onwochei, MBBS (1) · Elif Sagban Gedik, MD (1) · Eunmi Choi, MD.PhD (1) · Eva Pajkrt, Prof. Dr. (1) · Hina Mukhtar, MBBS (1) · Igor Michalec, M.D. (1)
PMID 24807330, PMID 14586323, PMID 16449104, PMID 18177834, PMID 18243484, PMID 22399222, PMID 23201330, PMID 23331924, PMID 26183455, PMID 26866031, PMID 26974218, PMID 28570639, PMID 30928565, PMID 32970845, PMID 34695232, PMID 36464242, PMID 37286317, PMID 37989370, PMID 40987744, PMID 41135925, PMID 42549482, PMID 9650373
2019 (1), 2023 (1), R01MD017947 (1)