8 completed, 7 recruiting, 5 active not recruiting, 2 terminated. 16 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow Post-traumatic Osteoarthritis: new trials by email Literature Review of Post-traumatic Osteoarthritis trials Research Report on Post-traumatic Osteoarthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Custom Dynamic Orthoses to Reduce Articular Contact Stress Carbon Fiber Custom Dynamic Orthosis (CDO) - Ankle Fractures, Post-traumatic Osteoarthritis | Not applicable | Withdrawn | University of Iowa | 2024-12-01 | 2026-01-15 | |
| Preventing Injured Knees From osteoArthritis: Severity Outcomes Metformin, Placebo - Osteoarthritis, Knee, Post-traumatic Osteoarthritis | Phase 2 | Recruiting | Brigham and Women's Hospital | 512 | 2024-05-06 | 2026-10-15 |
| Gait Rehabilitation to Treat FastOA Real-time gait biofeedback, Sham real-time gait biofeedback - Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 70 | 2023-06-13 | 2026-06-25 |
| Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics Carbon Fiber Custom Dynamic Orthosis (CDO) - Healthy, Lower Limb Injury | Not applicable | Completed | University of Iowa | 35 | 2023-05-17 | 2026-01-15 |
| Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA amobarbital/Gel-One (one dose), Placebo (single dose), amobarbital/Gel-One (two doses) - Osteoarthritis, Post-traumatic Osteoarthritis | Phase 1 / Phase 2 | Terminated | J L Marsh | 5 | 2022-07-20 | 2026-07-06 |
| PRP in ACLR to Prevent PTOA platelet rich plasma (PRP) injection, placebo saline injection - Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis | Phase 3 | Recruiting | Hospital for Special Surgery, New York | 56 | 2022-06-27 | 2026-02-13 |
| Physical Activity, Knee Joint Loading and Joint Health Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture | Unknown | University of Bath | 80 | 2022-06-01 | 2024-03-15 | |
| Insignia™ Hip Stem Outcomes Study Insignia uncemented Hip Stem - Hip Osteoarthritis, Avascular Necrosis | Not applicable | Active not recruiting | Stryker Orthopaedics | 313 | 2022-02-07 | 2026-05-18 |
| STABILITY: Physical Activity Intervention at 7 Years Post-Anterior Cruciate Ligament Reconstruction PARx - Anterior Cruciate Ligament Reconstruction, Post-traumatic Osteoarthritis | Not applicable | Active not recruiting | Western University, Canada | 196 | 2021-11-01 | 2025-05-13 |
| Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty Total hip arthroplasty (primary or revision) - Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis | Recruiting | Dedienne Sante S.A.S. | 747 | 2021-09-21 | 2024-08-27 | |
| Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention Real-time gait biofeedback, Sham real-time gait biofeedback - Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis | Not applicable | Completed | University of North Carolina, Chapel Hill | 24 | 2021-08-05 | 2023-04-18 |
| A Comparison of Impingement Free Range of Motion With CT Scan After Manual and Robotic Total Hip Replacement Manual Total Hip Replacement, Robot-Assisted Total Hip Replacement - Hip Osteoarthritis, Post-traumatic Osteoarthritis | Not applicable | Unknown | The Royal Orthopaedic Hospital NHS Trust | 50 | 2021-04-06 | 2023-09-08 |
| MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial) Montelukast, Placebo - ACL Injury, Meniscus Tear | Early Phase 1 | Recruiting | Austin V Stone | 30 | 2021-02-01 | 2026-06-10 |
| Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation - Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 114 | 2021-01-11 | 2025-05-31 |
| Freedom® Total Knee System for Treatment of Osteoarthritis, Rheumatoid Arthritis or Post-traumatic Arthritis Freedom® Total Knee System - Knee Osteoarthritis, Rheumatoid Arthritis | Not applicable | Not yet recruiting | Meril Life Sciences Pvt. Ltd. | 450 | 2021-01-01 | 2020-10-05 |
| Efficacy of an Evidence-based Telehealth Intervention in Modifying Health Behavior mCare PTOA Intervention - Post-traumatic Osteoarthritis, Knee Sprain | Not applicable | Active not recruiting | Keller Army Community Hospital | 65 | 2020-07-24 | 2026-09-30 |
| Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress Custom Carbon Fiber Dynamic Orthosis (CDO) - Ankle Fractures, Post-traumatic Osteoarthritis | Not applicable | Completed | University of Iowa | 22 | 2020-01-08 | 2026-01-30 |
| Ceramic-on-ceramic THA for Post-traumatic Hip Osteoarthritis After Acetabular Fracture ceramic-on-ceramic total hip arthroplasty - Hip Osteoarthritis, Post-traumatic Osteoarthritis | Completed | Istituto Ortopedico Rizzoli | 68 | 2019-07-15 | 2019-11-12 | |
| A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis Unicompartmental Biologic Arthroplasty, Extensive Biologic Arthroplasty - Knee Osteoarthritis, Post-traumatic Osteoarthritis | Not applicable | Completed | University of Missouri-Columbia | 14 | 2018-12-01 | 2022-11-02 |
| Establish Implant Accuracy With X-PSI Knee System X-PSI Knee System - Knee Osteoarthritis, Post-traumatic Osteoarthritis | Not applicable | Terminated | Zimmer, GmbH | 8 | 2018-10-05 | 2021-10-06 |
Showing 20 of 26. Sign in to see all of them.
Osteoarthritis, Knee (8) · Anterior Cruciate Ligament Injuries (7) · Arthritis, Rheumatoid (6) · Osteoarthritis (5) · Arthritis (4) · Osteoarthritis, Hip (4) · Ankle Fractures (3) · Knee Injuries (3) · Femoral Neck Fractures (2) · Motor Activity (2) · Osteonecrosis (2) · Femur Head Necrosis (1) · Fractures, Bone (1) · Hip Fractures (1) · Infections (1)
Joint Diseases (21) · Musculoskeletal Diseases (21) · Rheumatic Diseases (18) · Arthritis (17) · Wounds and Injuries (14) · Leg Injuries (13) · Osteoarthritis (12) · Autoimmune Diseases (6) · Connective Tissue Diseases (6) · Immune System Diseases (6) · Skin and Connective Tissue Diseases (6) · Fractures, Bone (5) · Knee Injuries (5) · Ankle Injuries (3) · Bone Diseases (3)
Arthroplasty, Replacement, Hip (2) · Injections (1) · Metformin (1) · Second-Look Surgery (1) · montelukast (1)
University of Iowa (3) · University of North Carolina, Chapel Hill (3) · J L Marsh (2) · Austin V Stone (1) · Brigham and Women's Hospital (1) · Dedienne Sante S.A.S. (1) · Exactech (1) · Hospital for Special Surgery, New York (1) · Istituto Ortopedico Rizzoli (1) · James Stannard (1) · Keller Army Community Hospital (1) · Meril Life Sciences Pvt. Ltd. (1) · Stryker Orthopaedics (1) · Stryker Trauma and Extremities (1) · The Royal Orthopaedic Hospital NHS Trust (1)
United States (17) · United Kingdom (5) · Canada (2) · France (2) · Germany (2) · Italy (2) · Austria (1) · Netherlands (1)
Jason M Wilken, PT, PhD (3) · James Stannard, MD (2) · Alfonso Romano, MD (1) · Alison Armstrong, MD (1) · Andrew Chambler, MD (1) · Angelo Di Giunta, MD (1) · Ari Youderian, MD (1) · Austin Stone, MD, PhD (1) · Ben Gooding, MD (1) · Ben Sears, MD (1) · Brad Carofino, MD (1) · Bradley Schoch, MD (1) · Brian Pietrosimone (1) · Brian Pietrosimone, PhD (1) · Bryan Butler, MD (1)
PMID 10507340, PMID 11407795, PMID 18534534, PMID 21474274, PMID 25034883, PMID 35101085, PMID 39867299, PMID 42777489, PMID 9759814