8 completed, 3 unknown, 1 withdrawn. 5 Phase 4, 3 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 3, Unknown 2 |
| Not applicable | 3 | Completed 2, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Post-operative Nausea and Vomiting: new trials by email Literature Review of Post-operative Nausea and Vomiting trials Research Report on Post-operative Nausea and Vomiting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion Hybrid anesthesia (propofol + sevoflurane), Propofol only TIVA - Post-operative Nausea and Vomiting | Phase 2 | Completed | Milton S. Hershey Medical Center | 65 | 2024-02-01 | 2026-08-14 |
| Aromatherapy in Total Knee Replacement Elequil Lavender-peppermint Aromatabs, Elequil Almond-Oil Aromatabs - Total Knee Replacement, Post-operative Nausea and Vomiting | Not applicable | Completed | Hospital for Special Surgery, New York | 30 | 2023-10-03 | 2025-01-27 |
| Multimodal Perioperative Pain Management: ComfortSafe Program ComfortSafe Care - Post-operative Pain, Post-operative Nausea and Vomiting | Unknown | Georgetown University | 60 | 2020-05-11 | 2020-10-05 | |
| Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial Lidocaine - Post-operative Pain, Post-operative Nausea and Vomiting | Phase 4 | Unknown | Aga Khan University Hospital, Pakistan | 120 | 2019-11-25 | 2019-12-03 |
| Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting. Oral Azithromycin tablet, Intravenous dexamethasone - Post-operative Nausea and Vomiting | Phase 4 | Unknown | Assiut University | 160 | 2019-06-01 | 2019-01-29 |
| Effects of Ondansetron Dose and Timing on Post-operative Nausea and Vomiting Ondansetron 4 MG, Ondansetron 8mg - Post-operative Nausea and Vomiting | Phase 4 | Completed | Icahn School of Medicine at Mount Sinai | 141 | 2017-10-23 | 2020-07-20 |
| Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia - Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy | Phase 4 | Completed | Stony Brook University | 83 | 2017-08-28 | 2024-02-14 |
| Mass-balance Study of [14C]-APD421 in Healthy Volunteers 14C-APD421 - Post-operative Nausea and Vomiting | Phase 1 | Completed | Acacia Pharma Ltd | 6 | 2016-08-01 | 2019-06-25 |
| Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV) Electrical Stimulation, Zofran, Dexamethasone - Post-Operative Nausea and Vomiting, Breast Cancer | Not applicable | Completed | M.D. Anderson Cancer Center | 188 | 2016-03-01 | 2025-12-05 |
| Overnight Use of Electroacustimulation on Postoperative Nausea and Vomiting in the Outpatient Surgery Population Battery-operated electroacustimulation device (Inactive), Battery-operated electroacustimulation device (Active) - Post-operative Nausea and Vomiting | Not applicable | Withdrawn | University of Wisconsin, Madison | 2011-06-01 | 2012-10-17 | |
| A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy granisetron - Post-Operative Nausea and Vomiting | Phase 4 | Completed | Hoffmann-La Roche | 171 | 2007-04-01 | 2018-03-27 |
| A Study to Examine the Safety and Tolerability of MK0517 for the Prevention of Post-Operative Nausea and Vomiting (0517-015) Comparator: MK0517, Comparator: ondansetron - Post-Operative Nausea and Vomiting | Phase 3 | Completed | Merck Sharp & Dohme LLC | 216 | 2005-07-01 | 2015-08-19 |
Vomiting (12) · Pain, Postoperative (3) · Anxiety Disorders (1) · Breast Neoplasms (1) · Depression (1) · Motion Sickness (1) · Nausea (1) · Postoperative Nausea and Vomiting (1) · Respiratory Insufficiency (1)
Pathological Conditions, Signs and Symptoms (12) · Signs and Symptoms (12) · Signs and Symptoms, Digestive (12) · Pathologic Processes (4) · Postoperative Complications (4) · Neurologic Manifestations (3) · Pain (3) · Behavior (1) · Behavioral Symptoms (1) · Breast Diseases (1) · Mental Disorders (1) · Nausea (1) · Neoplasms (1) · Neoplasms by Site (1) · Respiration Disorders (1)
Ondansetron (4) · Dexamethasone (2) · Propofol (2) · Sevoflurane (2) · Aprepitant (1) · Azithromycin (1) · Calcium Dobesilate (1) · Desflurane (1) · Dexmedetomidine (1) · Diphenhydramine (1) · Electric Stimulation (1) · Famotidine (1) · Fentanyl (1) · Granisetron (1) · Lidocaine (1)
Acacia Pharma Ltd (1) · Aga Khan University Hospital, Pakistan (1) · Assiut University (1) · Georgetown University (1) · Hoffmann-La Roche (1) · Hospital for Special Surgery, New York (1) · Icahn School of Medicine at Mount Sinai (1) · M.D. Anderson Cancer Center (1) · Merck Sharp & Dohme LLC (1) · Milton S. Hershey Medical Center (1) · Stony Brook University (1) · University of Wisconsin, Madison (1)
United States (8) · Netherlands (1) · Pakistan (1)
Alicia M. Kowalski, MD (1) · Benjamin Marcus, MD (1) · Daniel Katz, MD (1) · Dr. M. Umer Slote, MBBS (1) · Gabriel Fox, MB BChir (1) · Konstantinos Spaniolas, MD (1) · Sonal Sharma, MD (1) · Uchenna Umeh, MD (1)
PMID 17129308, PMID 17894152, PMID 21697139, PMID 22049287, PMID 22588767, PMID 23573142, PMID 23932834, PMID 26261829, PMID 27333231, PMID 27555173, PMID 27863613, PMID 28070420, PMID 28356304, PMID 31389832, PMID 31819674, PMID 32308715, PMID 32985338, PMID 33528788, PMID 34002866, PMID 34196978, PMID 34619742, PMID 34820153, PMID 35857151, PMID 40828687, PMID 41593496