5 completed, 2 recruiting, 2 unknown, 1 not yet recruiting. 3 Not applicable, 3 Phase 3, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Not yet recruiting 1 |
| Phase 3 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Pleural Empyema: new trials by email Literature Review of Pleural Empyema trials Research Report on Pleural Empyema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Antibiotic Course Upon Adequate Treatment of Empyema shortened antibiotic course, Standard medical treatment - Pleural Empyema | Not applicable | Not yet recruiting | University of Arizona | 50 | 2026-11-16 | 2026-10-07 |
| Chemical vs Mechanical Pleural Adhesiolysis for Liberation of Captive Pleura in Stacked Effusion Intrapleural Hydrogen Peroxide (H_2O_2), Intrapleural Corticosteroids, Thoracoscopic Mechanical Pleurolysis - Pleural Infection, Pleural Adhesions | Phase 2 | Completed | Delta University for Science and Technology | 36 | 2026-03-26 | 2026-07-20 |
| Fungal Empyema Thoracis pleural lavage followed by surgery, Decortication, Conservative Arm - Pyothorax, Fungal Infection Lungs | Not applicable | Recruiting | University of Health Sciences Lahore | 50 | 2025-07-01 | 2026-01-13 |
| VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema VATS group, Drain and intrapleural therapy group - Pleural Empyema | Not applicable | Recruiting | Thomas Decker Christensen | 184 | 2022-10-30 | 2025-10-03 |
| The Role of Decortication in Complex Empyema Cases: Multidrug Resistance and Tuberculosis at the Forefront Decortication - Pleural Empyema, Tuberculosis (TB) | Completed | University of Health Sciences Lahore | 350 | 2022-01-01 | 2025-09-15 | |
| The Oxford Pleural Infection Endotyping Study Pleural Infection, Pleural Diseases | Completed | University of Oxford | 80 | 2021-06-20 | 2024-07-22 | |
| A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation - Pleural Effusion, Malignant, Pleural Mesothelioma | Phase 4 | Unknown | Mohamed Reda Ashour | 40 | 2020-01-15 | 2021-10-14 |
| Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) TPA (Tissue Plasminogen Activator), DNase, Placebo - Pleural Empyema | Phase 3 | Completed | The Hospital for Sick Children | 97 | 2012-12-01 | 2020-04-14 |
| Procalcitonin in Pleural Pleuritis pleural level of procalcitonin - Pleuritis, Pleural Empyema | Completed | Centre Hospitalier Universitaire, Amiens | 34 | 2009-10-01 | 2016-06-09 | |
| Dornase Alfa and Urokinase for Kids With Pleural Empyema Urokinase and Dornase alfa, Urokinase - Pleural Empyema | Phase 2 / Phase 3 | Unknown | Azienda Ospedaliera di Padova | 94 | 2007-10-01 | 2008-05-12 |
| Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema Medical thoracoscopy, Simple chest tube drainage - Complicated Parapneumonic Effusion, Pleural Empyema | Phase 3 | Terminated | University Hospital, Basel, Switzerland | 2 | 2005-10-01 | 2016-05-24 |
Empyema, Pleural (11) · Empyema (3) · Pleural Effusion (3) · Pleural Diseases (2) · Hemothorax (1) · Inflammation (1) · Lung Diseases (1) · Mesothelioma, Malignant (1) · Pericardial Effusion (1) · Pleural Effusion, Malignant (1) · Pleural Neoplasms (1) · Pleurisy (1) · Pneumothorax (1) · Pulmonary Atelectasis (1) · Respiratory Aspiration (1)
Infections (11) · Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Respiratory Tract Diseases (11) · Respiratory Tract Infections (11) · Suppuration (11) · Inflammation (10) · Pleural Diseases (9) · Empyema (8) · Actinomycetales Infections (1) · Adenoma (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Cardiovascular Diseases (1) · Gram-Positive Bacterial Infections (1)
Cerebral Decortication (2) · dornase alfa (2) · Anesthesia, General (1) · Deoxyribonucleases (1) · Drainage (1) · One-Lung Ventilation (1) · Saline Solution (1) · Tissue Plasminogen Activator (1) · Urokinase-Type Plasminogen Activator (1)
University of Health Sciences Lahore (2) · Azienda Ospedaliera di Padova (1) · Centre Hospitalier Universitaire, Amiens (1) · Delta University for Science and Technology (1) · Mohamed Reda Ashour (1) · The Hospital for Sick Children (1) · Thomas Decker Christensen (1) · University Hospital, Basel, Switzerland (1) · University of Arizona (1) · University of Oxford (1)
Egypt (2) · Italy (2) · Pakistan (2) · Canada (1) · Denmark (1) · France (1) · Greece (1) · Switzerland (1) · United Kingdom (1) · United States (1)
Ahmed F Koraitim, MD (1) · Christian B Laursen, MD, PhD (1) · Eyal Cohen, MD, MSc (1) · Giorgio Stefanutti, MD (1) · Hany H El Sayed, Professor (1) · Martin H Brutsche, MD, Prof. (1) · Muhammad Shoaib Nabi, FCPS (1) · Muhammad Shoaib Nabi, Professor of Thoracic Surgery (1) · PierGiorgio Gamba, MD (1) · Stephanie Worrell, MD (1) · Waleed El Taher, Professor (1)