17 unknown. 17 Phase 2, 5 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Unknown 17 |
| Phase 3 | 5 | Unknown 5 |
| Phase 1 | 3 | Unknown 3 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural Effusion bevacizumab and camrelizumab - Malignant Pleural Effusion | Phase 1 / Phase 2 | Unknown | The First Affiliated Hospital of Zhengzhou University | 55 | 2022-08-01 | 2022-04-15 |
| A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites BSG-001 - Malignant Pleural Effusion, Malignant Ascites | Phase 1 / Phase 2 | Unknown | BioSyngen Pte Ltd | 58 | 2019-01-01 | 2018-11-08 |
| Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis Silver Nitrate, Indwelling Pleural Catheter - Pleural Effusion, Malignant | Phase 1 / Phase 2 | Unknown | Assiut University | 50 | 2019-01-01 | 2018-12-20 |
| A Randomized Study of Primary Tumor Radiotherapy for Patients With MPE Stage IV NSCLC Radiation, Chemotherapy - Malignant Pleural Effusion, Nonsmall Cell Lung Cancer, Stage IV | Phase 2 | Unknown | Guizhou Medical University | 68 | 2018-09-01 | 2019-06-14 |
| Bevacizumab in the Treatment of Malignant Pleural Effusions of Non-squamous Non-small Cell Lung Cancer Bevacizumab - Malignant Pleural Effusion | Phase 2 | Unknown | Peking University Cancer Hospital & Institute | 87 | 2016-10-01 | 2018-11-07 |
| Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion tumor derived microparticles, cisplatin - Malignant Pleural Effusion | Phase 2 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 90 | 2016-01-01 | 2019-02-26 |
| Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural Effusion rAdp53, Cisplatin, rAdp53 plus cisplatin - Malignant Pleural Effusion | Phase 2 | Unknown | Shenzhen SiBiono GeneTech Co.,Ltd | 90 | 2015-06-01 | 2015-04-29 |
| Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax Thoracoscopic bullectomy and pleural abrasion, Mesh coverage of the staple line - Spontaneous Pneumothorax, Surgery | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 204 | 2013-05-01 | 2015-07-08 |
| Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion Drug-packaging microparticles - Malignant Pleural Effusion,, Malignant Ascites | Phase 2 | Unknown | Huazhong University of Science and Technology | 30 | 2013-05-01 | 2013-10-01 |
| Efficacy and Safety of Bevacizumab Versus Pulvis Talci in Malignant Pleural Effusion Bevacizumab, Pulvis talci - Malignant Pleural Effusion | Phase 2 | Unknown | Tang-Du Hospital | 183 | 2012-01-01 | 2014-02-04 |
| Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure OROTRACHEAL cpap WITH COMPENSATION BAG ( GREGORY CPAP) - Neonatal Respiratory Failure | Phase 2 / Phase 3 | Unknown | Hospital Angeles del Pedregal | 100 | 2011-06-01 | 2011-06-23 |
| Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population Doxycycline, normal saline - Malignant Pleural Effusion | Phase 2 | Unknown | Ottawa Hospital Research Institute | 40 | 2011-06-01 | 2020-09-25 |
| Safety and Effectiveness Study for Pleurodesis With Silver Nitrate in Malignant Pleural Effusion Silver Nitrate - Malignant Pleural Effusion | Phase 2 | Unknown | University of Sao Paulo General Hospital | 60 | 2009-08-01 | 2010-05-18 |
| Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Video-assisted thoracoscopic surgery, chest tube drainage - Pneumothorax | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 60 | 2008-04-01 | 2012-12-17 |
| Dornase Alfa and Urokinase for Kids With Pleural Empyema Urokinase and Dornase alfa, Urokinase - Pleural Empyema | Phase 2 / Phase 3 | Unknown | Azienda Ospedaliera di Padova | 94 | 2007-10-01 | 2008-05-12 |
| Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion ibuprofen, morphine sulfate, management of therapy complications - Metastatic Cancer | Phase 2 | Unknown | Oxford University Hospitals NHS Trust | 320 | 2007-03-01 | 2009-07-08 |
| Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax 1 apical pleurectomy, 2 pleural abrasion + minocycline pleurodesis - Pneumothorax | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 200 | 2005-04-01 | 2006-08-07 |
Pleural Effusion, Malignant (12) · Pneumothorax (4) · Pleural Effusion (2) · Ascites (1) · Carcinoma, Non-Small-Cell Lung (1) · Empyema, Pleural (1) · Neoplasm Metastasis (1) · Pain (1) · cyclopia sequence (1)
Respiratory Tract Diseases (17) · Neoplasms (12) · Neoplasms by Site (12) · Pleural Neoplasms (12) · Respiratory Tract Neoplasms (12) · Thoracic Neoplasms (12) · Pleural Effusion (11) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Empyema (1) · Infections (1) · Inflammation (1)
Bevacizumab (3) · Cisplatin (2) · Silver Nitrate (2) · Doxycycline (1) · Drug Therapy (1) · Ibuprofen (1) · Morphine (1) · Pleurodesis (1) · Radiation (1) · Saline Solution (1) · Thoracic Surgery, Video-Assisted (1) · Urokinase-Type Plasminogen Activator (1) · camrelizumab (1) · dornase alfa (1)
National Taiwan University Hospital (3) · Assiut University (1) · Azienda Ospedaliera di Padova (1) · BioSyngen Pte Ltd (1) · Guizhou Medical University (1) · Hospital Angeles del Pedregal (1) · Huazhong University of Science and Technology (1) · Ottawa Hospital Research Institute (1) · Oxford University Hospitals NHS Trust (1) · Peking University Cancer Hospital & Institute (1) · Shenzhen SiBiono GeneTech Co.,Ltd (1) · Tang-Du Hospital (1) · The First Affiliated Hospital of Zhengzhou University (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Sao Paulo General Hospital (1)
China (6) · Taiwan (3) · Australia (1) · Brazil (1) · Canada (1) · Italy (1) · United Kingdom (1)
Jin-Shing Chen, MD, PhD (2) · Yung-Chie Lee, MD, PhD (2) · Bo Huang, Ph.D (1) · Feng Wang (1) · Giorgio Stefanutti, MD (1) · Jian Fang (1) · K. Amjadi, MD, FRCPC (1) · Lietao Li, MD (1) · PierGiorgio Gamba, MD (1) · Ricardo M Terra, MD (1) · Robert Davies, MD (1) · Yang Jin, doctor (1)
PMID 16107633, PMID 16111068, PMID 16790519, PMID 16797681, PMID 16940982, PMID 18561992, PMID 18710781, PMID 21267391, PMID 22083202, PMID 22323011, PMID 23178954, PMID 23925664, PMID 25798278, PMID 33279544, PMID 35080187