10 terminated. 10 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Terminated 10 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 1 | Terminated 1 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion Talimogene laherparepvec (TVEC), Nivolumab - Malignant Pleural Effusion, Stage IV Metastatic Cancer | Phase 1 / Phase 2 | Terminated | UNC Lineberger Comprehensive Cancer Center | 1 | 2019-03-06 | 2021-04-20 |
| The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection Naproxen, Placebo - Pleural Effusion, Pleural Effusion Malignant | Phase 2 | Terminated | McMaster University | 7 | 2014-04-01 | 2018-02-15 |
| Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion immediate cediranib, Start cediranib after 28 days Best Supportive Care - Malignant Ascites, Malignant Pleural Effusion | Phase 2 | Terminated | Radboud University Medical Center | 12 | 2010-04-01 | 2013-07-15 |
| Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer zoledronic acid - Malignant Pleural Effusion, Non Small Cell Lung Cancer | Phase 2 | Terminated | Peter Bushunow MD | 3 | 2009-11-01 | 2012-12-04 |
| QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer AMG 479, Etoposide, Placebo - Lung Cancer, Small Cell Lung Cancer | Phase 1 / Phase 2 | Terminated | NantCell, Inc. | 213 | 2008-12-02 | 2024-08-23 |
| Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy normal saline, TNK (Tenecteplase) - Pleural Effusion | Phase 2 / Phase 3 | Terminated | Kaiser Permanente | 20 | 2008-01-01 | 2026-04-14 |
| Level of Continuous Positive Airway Pressure (CPAP) in Preterm Infants After Extubation (L-CPAP Study) Nasal CPAP, level 7 to 9 cmH2O, Nasal CPAP, level 4 to 6 cmH2O - Respiratory Insufficiency of Prematurity | Phase 2 | Terminated | Hamilton Health Sciences Corporation | 23 | 2007-07-01 | 2009-02-10 |
| Positron Emission Tomography and Computed Tomography in Planning Treatment for Patients Undergoing 3-Dimensional Conformal Radiation Therapy for Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery. ICORG 06-35 computed tomography, 3-dimensional conformal radiation therapy, fludeoxyglucose F 18 - Lung Cancer, Metastatic Cancer | Phase 2 | Terminated | Cancer Trials Ireland | 40 | 2007-03-01 | 2017-05-24 |
| Malignant Pleural Effusion With ZD6474 ZD6474 - Lung Cancer, Pleural Effusion | Phase 2 | Terminated | M.D. Anderson Cancer Center | 28 | 2006-10-01 | 2016-03-09 |
| Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura chemotherapy, porfimer sodium, immunohistochemistry staining method - Lung Cancer, Metastatic Cancer | Phase 2 | Terminated | Abramson Cancer Center at Penn Medicine | 9 | 2004-11-01 | 2020-11-24 |
Pleural Effusion, Malignant (7) · Lung Neoplasms (6) · Carcinoma, Non-Small-Cell Lung (4) · Neoplasm Metastasis (3) · Pleural Effusion (3) · Adenocarcinoma of Lung (1) · Lung Injury (1) · Neoplasms (1) · Pneumothorax (1) · Respiratory Distress Syndrome (1) · Respiratory Insufficiency (1) · Small Cell Lung Carcinoma (1)
Respiratory Tract Diseases (10) · Lung Diseases (8) · Neoplasms (8) · Neoplasms by Site (8) · Respiratory Tract Neoplasms (8) · Thoracic Neoplasms (8) · Pleural Neoplasms (7) · Pleural Effusion (6) · Bronchial Neoplasms (5) · Carcinoma, Bronchogenic (5) · Neoplastic Processes (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Adenocarcinoma (1)
Carboplatin (1) · Cisplatin (1) · Dihematoporphyrin Ether (1) · Drug Therapy (1) · Etoposide (1) · Fluorodeoxyglucose F18 (1) · Immunohistochemistry (1) · Naproxen (1) · Nivolumab (1) · Radiotherapy, Conformal (1) · Receptors, Vascular Endothelial Growth Factor (1) · Saline Solution (1) · Spectrum Analysis (1) · Tenecteplase (1) · Zoledronic Acid (1)
Abramson Cancer Center at Penn Medicine (1) · Cancer Trials Ireland (1) · Hamilton Health Sciences Corporation (1) · Kaiser Permanente (1) · M.D. Anderson Cancer Center (1) · McMaster University (1) · NantCell, Inc. (1) · Peter Bushunow MD (1) · Radboud University Medical Center (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (5) · Canada (1) · Ireland (1) · Netherlands (1)
Carlos Jimenez, M.D. (1) · Giulherme M SantAnna, MD (1) · Hyo-Chun Yoon, MD (1) · Jared Weiss, MD (1) · Keith Cengel, MD, PhD (1) · Kevin Lightner, M.D. (1) · Peter Bushunow, M.D. (1) · Pierre Thirion, MD (1) · Todd Sheppard, M.D. (1) · Yaron Shargall, MD, BSc, FRCSC (1)